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Journal of Clinical Monitoring and Computing

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01-06-2019 | Editorial

Perioperative goal-directed therapy: what’s the best study design to investigate its impact on patient outcome?

Authors: Bernd Saugel, Alexandre Joosten, Thomas W. L. Scheeren

Published in: Journal of Clinical Monitoring and Computing | Issue 3/2019

Excerpt

The impact of anesthetic management on short and long-term postoperative outcomes is a subject of current research in anesthesiology [1]. There is increasing evidence that certain aspects of anesthetic management—including perioperative goal-directed blood flow and fluid optimization [2, 3] and monitoring of the depth of anesthesia [4, 5]—can have a beneficial impact on postoperative complication rates. …

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Ho AMH, Phelan R, Mizubuti GB, et al. Bias in before-after studies: narrative overview for anesthesiologists. Anesth Analg. 2018;126:1755–62. https://doi.org/10.1213/ane.0000000000002705.CrossRefPubMed

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Cannesson M, Ramsingh D, Rinehart J, et al. Perioperative goal-directed therapy and postoperative outcomes in patients undergoing high-risk abdominal surgery: a historical-prospective, comparative effectiveness study. Crit Care. 2015;19:261. https://doi.org/10.1186/s13054-015-0945-2.CrossRefPubMedPubMedCentral

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Joosten A, Coeckelenbergh S, Delaporte A, et al. Implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during major abdominal surgery: a case-control study with propensity matching. Eur J Anaesthesiol. 2018;35:650–8. https://doi.org/10.1097/eja.0000000000000827.CrossRefPubMed

Title: Perioperative goal-directed therapy: what’s the best study design to investigate its impact on patient outcome?
Authors: Bernd Saugel
Alexandre Joosten
Thomas W. L. Scheeren
Publication date: 01-06-2019
Publisher: Springer Netherlands
Published in: Journal of Clinical Monitoring and Computing / Issue 3/2019
Print ISSN: 1387-1307
Electronic ISSN: 1573-2614
DOI: https://doi.org/10.1007/s10877-018-0196-2

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Perioperative goal-directed therapy: what’s the best study design to investigate its impact on patient outcome?

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Keynote webinar | Spotlight on medication adherence

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