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Journal of Clinical Monitoring and Computing

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01-12-2017 | Letter to the Editor

In response to: “understanding elevated P_v−aCO₂ gap and P_v−aCO₂/C_a−vO₂ ratio in venous hyperoxia condition”

Authors: P. Saludes, L. Proença, G. Gruartmoner, L. Enseñat, A. Pérez-Madrigal, C. Espinal, J. Mesquida

Published in: Journal of Clinical Monitoring and Computing | Issue 6/2017

Excerpt

We have read with great interest the letter by He et al., where several concerns regarding our recently published work in the journal [1] are stressed. We want to thank the authors for their critical analysis of our interpretation of the data, and we celebrate that the subject is a matter of debate, which to our understanding, underlines the relevance this topic has gained in the recent years. …

Saludes P, Proença L, Gruartmoner G, Enseñat L, Pérez-Madrigal A, Espinal C, Mesquida J. Central venous-to-arterial carbon dioxide difference and the effect of venous hyperoxia: a limiting factor, or an additional marker of severity in shock? J Clin Monit Comput 2016. [Epub ahead of print].

Orbegozo Cortés D, Puflea F, Donadello K, Taccone FS, Gottin L, Creteur J, et al. Normobaric hyperoxia alters the microcirculation in healthy volunteers. Microvasc Res. 2015;98:23–8.CrossRefPubMed

Milstein DM, Helmers R, Hackmann S, Belterman CN, van Hulst RA, de Lange J. Sublingual microvascular perfusion is altered during normobaric and hyperbaric hyperoxia. Microvasc Res. 2016;105:93–102.CrossRefPubMed

Teboul JL, Scheeren T. Understanding the Haldane effect. Intensive Care Med. 2017;43(1):91–3.CrossRefPubMed

Mekontso-Dessap A, Castelain V, Anguel N, Bahloul M, Schauvliege F, Richard C, et al. Combination of venoarterial PCO₂ difference with arteriovenous O₂ content difference to detect anaerobic metabolism in patients. Intensive Care Med. 2002;28:272–7.CrossRefPubMed

Mesquida J, Saludes P, Gruartmoner G, Espinal C, Torrents E, Baigorri F, et al. Central venous-to-arterial carbon dioxide difference combined with arterial-to-venous oxygen content difference is associated with lactate evolution in the hemodynamic resuscitation process in early septic shock. Crit Care. 2015;19:126.CrossRefPubMedPubMedCentral

Mallat J, Lemyze M, Meddour M, Pepy F, Gasan G, Barrallier S, et al. Ratios of central venous-to-arterial carbon dioxide content or tension to arteriovenous oxygen content are better markers of global anaerobic metabolism than lactate in septic shock patients. Ann Intensive Care. 2016;6:10.CrossRefPubMedPubMedCentral

Title: In response to: “understanding elevated Pv−aCO2 gap and Pv−aCO2/Ca−vO2 ratio in venous hyperoxia condition”
Authors: P. Saludes
L. Proença
G. Gruartmoner
L. Enseñat
A. Pérez-Madrigal
C. Espinal
J. Mesquida
Publication date: 01-12-2017
Publisher: Springer Netherlands
Published in: Journal of Clinical Monitoring and Computing / Issue 6/2017
Print ISSN: 1387-1307
Electronic ISSN: 1573-2614
DOI: https://doi.org/10.1007/s10877-017-0006-2

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In response to: “understanding elevated P_v−aCO₂ gap and P_v−aCO₂/C_a−vO₂ ratio in venous hyperoxia condition”

Excerpt

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