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Journal of Clinical Immunology
Published in: Journal of Clinical Immunology 4/2017

01-05-2017 | Letter to Editor

Persistent Impairment of T-Cell Regeneration in a Patient with Activated PI3K δ Syndrome

Authors: Fumihiro Goto, Toru Uchiyama, Yumiko Nakazawa, Kohsuke Imai, Toshinao Kawai, Masafumi Onodera

Published in: Journal of Clinical Immunology | Issue 4/2017

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Excerpt

To the Editor: …
Appendix
Available only for authorised users
Literature
1.
Angulo I, Vadas O, Garcon F, Banham-Hall E, Plagnol V, et al. Phosphoinositide 3-kinase delta gene mutation predisposes to respiratory infection and airway damage. Science. 2013;342(6160):866–71.CrossRefPubMedPubMedCentral
2.
Lucas CL, Kuehn HS, Zhao F, Niemela JE, Deenick EK, et al. Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110delta result in T cell senescence and human immunodeficiency. Nat Immunol. 2014;15(1):88–97.CrossRefPubMed
3.
Rae W, Ramakrishnan KA, Gao Y, Ashton-Key M, Pengelly RJ, et al. Precision treatment with sirolimus in a case of activated phosphoinositide 3-kinase delta syndrome. Clin Immunol. 2016;171:38–40.CrossRefPubMed
4.
Chapman NM, Chi HB. mTOR links environmental signals to T cell fate decisions. Front Immunol. 2015;5:1–11.CrossRef
5.
Kerdiles YM, Beisner DR, Tinoco R, Dejean AS, Castrillon DH, et al. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nat Immunol. 2009;10(2):176–84.CrossRefPubMedPubMedCentral
Metadata
Title
Persistent Impairment of T-Cell Regeneration in a Patient with Activated PI3K δ Syndrome
Authors
Fumihiro Goto
Toru Uchiyama
Yumiko Nakazawa
Kohsuke Imai
Toshinao Kawai
Masafumi Onodera
Publication date
01-05-2017
Publisher
Springer US
Published in
Journal of Clinical Immunology / Issue 4/2017
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI
https://doi.org/10.1007/s10875-017-0393-7

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