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Journal of Assisted Reproduction and Genetics

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01-03-2020 | Preimplantation Genetic Diagnostics | Commentary

Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed

Authors: Raoul Orvieto, Norbert Gleicher

Published in: Journal of Assisted Reproduction and Genetics | Issue 3/2020

Excerpt

Natural fecundity of women decreases gradually and more rapidly after age 37 years. This decrease is accompanied by rising aneuploidy rates of pregnancies and can also be observed in products of conception of spontaneous abortions [1]. These observations lead to the hypothesis that transferring only euploid embryos in association with in vitro fertilization (IVF) might decrease miscarriages and increase live birth rates (LBRs), attesting-procedure now called preimplantation genetic testing (of embryos) for aneuploidy (PGT-A), until recently generally referred to as preimplantation genetic screening (PGS). …

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Title: Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed
Authors: Raoul Orvieto
Norbert Gleicher
Publication date: 01-03-2020
Publisher: Springer US
Keywords: Preimplantation Genetic Diagnostics
Miscarriage
Published in: Journal of Assisted Reproduction and Genetics / Issue 3/2020
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-020-01705-w

2024 ASCO Annual Meeting

Springer Medicine

Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

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The PGS/PGT-A controversy in IVF addressed as a formal conflict resolution analysis

Ovarian stimulation is a safe and effective fertility preservation option in the adolescent and young adult population

The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers