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Journal of Assisted Reproduction and Genetics

Published in:

01-10-2009 | Assisted Reproduction

Impact of the size of zona pellucida thinning area on vitrified-warmed cleavage-stage embryo transfers: a prospective, randomized study

Authors: Kenichiro Hiraoka, Kaori Hiraoka, Toshitaka Horiuchi, Tomoyo Kusuda, Shinichiro Okano, Masayuki Kinutani, Kazuo Kinutani

Published in: Journal of Assisted Reproduction and Genetics | Issue 9-10/2009

Abstract

Purpose

The aim of this study was to determine if the size of zona pellucida thinning area by laser assisted hatching could affect the rates of pregnancy and implantation for vitrified-warmed embryo transfers at the cleavage-stage.

Methods

A total of 120 vitrified-warmed cleavage-stage embryo transfers were randomly assigned to either quarter or half of zona pellucida thinning group.

Results

The rates of clinical pregnancy (46.7 versus 25.0%) and implantation (32.0 versus 16.2%) were significantly greater in the half thinning group than in the quarter thinning group (P = 0.0218 and P = 0.0090, respectively).

Conclusions

The results of this investigation show that, in vitrified-warmed embryo transfers at the cleavage-stage, the size of zona pellucida thinning area by laser assisted hatching impacts the rate of clinical pregnancy and implantation and that half of zona pellucida thinning significantly increases both of these results compared with quarter of zona pellucida thinning.

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Title: Impact of the size of zona pellucida thinning area on vitrified-warmed cleavage-stage embryo transfers: a prospective, randomized study
Authors: Kenichiro Hiraoka
Kaori Hiraoka
Toshitaka Horiuchi
Tomoyo Kusuda
Shinichiro Okano
Masayuki Kinutani
Kazuo Kinutani
Publication date: 01-10-2009
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 9-10/2009
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-009-9350-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impact of the size of zona pellucida thinning area on vitrified-warmed cleavage-stage embryo transfers: a prospective, randomized study

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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