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Journal of Assisted Reproduction and Genetics

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01-10-2007 | Original Papers

Intramuscular route of progesterone administration increases pregnancy rates during non-downregulated frozen embryo transfer cycles

Authors: Ghassan Haddad, Docile A. Saguan, Rose Maxwell, Michael A. Thomas

Published in: Journal of Assisted Reproduction and Genetics | Issue 10/2007

Abstract

Objective

The optimal route of progesterone (P4) administration in embryo transfer (FET) cycles remains to be determined. The objective of this study is to compare the pregnancy outcomes between intramuscular (IM) and vaginal progesterone (PV) administration for endometrial preparation in non-donor FET cycles.

Study design

A retrospective clinical study in a private practice infertility setting.

Results

No significant differences in patient demographics and embryo characteristics were noted between the two groups. The clinical pregnancy rate as well as the live birth rate were significantly higher in the IM arm compared to the PV arm (38.2% vs 28%, 34.5 % vs 22.8%, respectively).

Conclusion

Although both routes of progesterone administration had similar rates of initial positive pregnancy tests, the IM route had a significantly higher live birth rate. The exact reason for this difference remains to be determined.

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Title: Intramuscular route of progesterone administration increases pregnancy rates during non-downregulated frozen embryo transfer cycles
Authors: Ghassan Haddad
Docile A. Saguan
Rose Maxwell
Michael A. Thomas
Publication date: 01-10-2007
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 10/2007
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-007-9168-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Intramuscular route of progesterone administration increases pregnancy rates during non-downregulated frozen embryo transfer cycles

Abstract

Objective

Study design

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Study design

Results

Conclusion

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