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International Ophthalmology
Published in: International Ophthalmology 4/2018

01-08-2018 | Case Report

Optical coherence tomography angiography findings in Susac’s syndrome: a case report

Authors: Rodolfo Mastropasqua, Lisa Toto, Alfonso Senatore, Alessandro D’Uffizi, Piergiorgio Neri, Cesare Mariotti, Marica Tina Maccarone, Luca Di Antonio

Published in: International Ophthalmology | Issue 4/2018

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Abstract

Purpose

To report clinical features of Susac’s syndrome (SS) using optical coherence tomography angiography (OCTA).

Methods

Case report.

Results

A 25-year-old Caucasian female with a history of non-pulsatile migraine, tinnitus, and verbal apraxia complaining of peripheral scotoma in left eye due to branch retinal arteriole occlusion (BRAO) was diagnosed as having SS after audiometric test, brain magnetic resonance imaging, and multimodal retinal imaging. Fundus biomicroscopy and fluorescein angiography (FA) revealed the presence of retinal ischemia in the area of BRAO. The OCTA images showed decreased vascular perfusion of both superficial and deep plexuses in the area of the occluded arteriole with increase of vascular density values after treatment with intravenous glucocorticoids, cyclophosphamide, and aspirin.

Conclusions

OCTA offers a valid alternative to the standard invasive FA, evaluating vascular perfusion in all capillary plexuses, and monitoring retinal microvascular flow changes during the course of BRAO, without dye injection.
Literature
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Agarwal A, Soliman M, Sarwar S, Sadiq MA, Do DV, Nguyen QD, Sepah YJ (2016) Spectral-domain optical coherence tomography evaluation of retinal structure in patients with Susacs syndrome. Retin Cases Brief Rep 0:1–3
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Mastropasqua R, Di Antonio L, Di Staso S, Agnifili L, Di Gregorio A, Ciancaglini M, Mastropasqua L (2015) Optical coherence tomography angiography in retinal vascular diseases and choroidal neovascularization. J Ophthalmol 2015:343515CrossRefPubMedPubMedCentral
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Metadata
Title
Optical coherence tomography angiography findings in Susac’s syndrome: a case report
Authors
Rodolfo Mastropasqua
Lisa Toto
Alfonso Senatore
Alessandro D’Uffizi
Piergiorgio Neri
Cesare Mariotti
Marica Tina Maccarone
Luca Di Antonio
Publication date
01-08-2018
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 4/2018
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-017-0653-9

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