Published in:
01-10-2019 | META-ANALYSIS
Green tea consumption and mortality in Japanese men and women: a pooled analysis of eight population-based cohort studies in Japan
Authors:
Sarah Krull Abe, Eiko Saito, Norie Sawada, Shoichiro Tsugane, Hidemi Ito, Yingsong Lin, Akiko Tamakoshi, Junya Sado, Yuri Kitamura, Yumi Sugawara, Ichiro Tsuji, Chisato Nagata, Atsuko Sadakane, Taichi Shimazu, Tetsuya Mizoue, Keitaro Matsuo, Mariko Naito, Keitaro Tanaka, Manami Inoue, Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Published in:
European Journal of Epidemiology
|
Issue 10/2019
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Abstract
The aim of our study was to assess the association between green tea consumption and all-cause and cause-specific mortality in a pooled analysis of eight Japanese population-based cohort studies. Pooled hazard ratios (HR) and 95% confidence intervals (CI), derived from random effects models, were used to evaluate the associations between green tea consumption, based on self-report at baseline, and risk of all-cause and cause-specific mortality. During a mean follow-up of 17.3 years, among 313,381 persons, 52,943 deaths occurred. Compared with individuals who consumed < 1 cup/day, those in the highest consumption category (≥ 5 cups/day) had a decreased risk of all-cause mortality [the multivariate-adjusted HR was 0.90 (95% CI 0.87–0.94) for men and 0.82 (0.74–0.90) for women]. A similar inverse association was observed for heart disease mortality [HR 0.82 (0.75–0.90) for men, and 0.75 (0.68–0.84) for women], and cerebrovascular disease mortality [HR 0.76 (0.68–0.85) for men, and 0.78 (0.68–0.89) for women]. Among women, green tea consumption was associated with decreased risk of total cancer mortality: 0.89 (0.83–0.96) for the 1–2 cups/day category and 0.91 (0.85–0.98) for the 3–4 cups/day category. Results for respiratory disease mortality were [HR 0.75 (0.61–0.94)] among 3–4 cup daily consumers and [HR 0.66 (0.55–0.79)] for ≥ 5 cups/day. Higher consumption of green tea is associated with lower risk for all-cause mortality in Japanese, especially for heart and cerebrovascular disease. Moderate consumption decreased the risk of total cancer and respiratory disease mortality in women.