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Documenta Ophthalmologica

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01-12-2018 | Original Research Article

Role of a mydriasis-free, full-field flicker ERG device in the detection of diabetic retinopathy

Authors: Mehmet Fatih Kağan Değirmenci, Sibel Demirel, Figen Batıoğlu, Emin Özmert

Published in: Documenta Ophthalmologica | Issue 3/2018

Abstract

Purpose

To determine if the RETeval system can be used for the screening of diabetic retinopathy (DR) to provide early diagnosis.

Methods

The subjects were 42 diabetic patients selectively recruited by examination of their medical records to have varying severities of DR. The severity of DR was classified into four groups according to the International Clinical Diabetic Retinopathy Disease Severity Scale. Full-field electroretinograms (ERG) without mydriasis were obtained by the DR assessment protocol of the RETeval system. Macular retinal nerve fiber layer (RNFL) thickness was measured by optical coherence tomography. We compared the DR assessment protocol results and the macular RNFL thickness among four groups. Moreover, an analysis was conducted on whether there was any correlation among the DR assessment protocol results, duration of diabetes mellitus, and RNFL thickness individually for each group of patients.

Results

The mean ages and mean duration of diabetes mellitus of the four groups were similar. The DR assessment protocol results in the moderate–severe nonproliferative DR, and proliferative DR groups were significantly higher than those in the other groups (p < 0.001). The mean macular RNFL thickness was similar in all groups. No significant correlation was found between the DR assessment protocol results and duration of DM and the RNFL thickness.

Conclusions

Our results suggest that the RETeval full-field ERG system can be used as an adjunctive tool for the mass screening of DR, while macular RNFL thickness would not be useful.

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Title: Role of a mydriasis-free, full-field flicker ERG device in the detection of diabetic retinopathy
Authors: Mehmet Fatih Kağan Değirmenci
Sibel Demirel
Figen Batıoğlu
Emin Özmert
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: Documenta Ophthalmologica / Issue 3/2018
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI: https://doi.org/10.1007/s10633-018-9656-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Role of a mydriasis-free, full-field flicker ERG device in the detection of diabetic retinopathy

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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