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01-09-2007 | Original Research Article

Within-session reproducibility of motion-onset VEPs: Effect of adaptation/habituation or fatigue on N2 peak amplitude and latency

Authors: Jan Kremláček, Miroslav Kuba, Zuzana Kubová, Jana Langrová, František Vít, Jana Szanyi

Published in: Documenta Ophthalmologica | Issue 2/2007

Abstract

We explored the effect of repeated visual stimulation on motion-onset visual evoked potentials (M-VEPs) during 25 min recording sessions in 10 subjects. The aim of the experiment was to determine influence of global motion adaptation (without motion-aftereffect) on intra-individual variability of M-VEPs and to suggest an optimal recording design for clinical examination. In addition to well described middle-time sensory adaptation, we also observed a long-time effect on motion specific N2 peak (155 ms). The N2 peak exhibited a strong relationship between its latency and inter-peak amplitude to the duration of recording in occipito-parietal derivations. In addition to the middle-term adaptation, N2 peak latency was prolonged by 10 ms and amplitude was attenuated by 30% with respect to the start of the experiment. An exponential model was employed to describe the dependency. The model can be used to reduce intra-individual variability during examination. Observed resemblance between the measured electrophysiological values and already published metabolic changes (glucose and oxygen utilization) during brain processing of visual information is discussed.

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Title: Within-session reproducibility of motion-onset VEPs: Effect of adaptation/habituation or fatigue on N2 peak amplitude and latency
Authors: Jan Kremláček
Miroslav Kuba
Zuzana Kubová
Jana Langrová
František Vít
Jana Szanyi
Publication date: 01-09-2007
Publisher: Springer-Verlag
Published in: Documenta Ophthalmologica / Issue 2/2007
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI: https://doi.org/10.1007/s10633-007-9063-z

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Within-session reproducibility of motion-onset VEPs: Effect of adaptation/habituation or fatigue on N2 peak amplitude and latency

Abstract

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Abstract

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