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Published in: Digestive Diseases and Sciences 6/2016

01-06-2016 | Editorial

Providing Deep Sedation for Advanced Endoscopic Procedures: The Esthetics of Endoscopic Anesthetics

Authors: Basavana Goudra, Preet Mohinder Singh

Published in: Digestive Diseases and Sciences | Issue 6/2016

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Excerpt

With gastroenterologists firmly established as therapeutic endoscopists, the anesthesia requirements for advanced endoscopic procedures are approaching those of specialized surgical interventions. It is often stated that although there are minor surgeries, there is no such thing as minor anesthetics. Stated another way, “monitored anesthesia care” (more recently referred to as “deep sedation”) is just as risky as general anesthesia administered in a standard operating room (OR). Indeed, the available evidence suggests that the risks of providing anesthesia in locations such as endoscopy suites are higher than in conventional ORs. Our own study highlighted the dangers of providing deep sedation for patients undergoing all types of endoscopic procedures: The risk of propofol sedation for interventional procedures such as endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasound, and therapeutic endoscopy are among the highest for any sedated endoscopic procedure. The reasons are many: The intensity of stimulation encountered during these procedures is similar to many minor surgeries; the airway management is complex and requires constant attention; the incidence of hypoxemia is high, and the time available for recognition and management is limited; and finally, there are several cases of venous air embolism reported during ERCP and esophageal balloon dilation [13]. In our analysis, we cited studies such as one by Metzner et al. [4] who in their analysis of anesthesia-related claims concluded that ~50 % of all out-of-OR-related deaths occurred during gastrointestinal (GI) endoscopy, and about half of these deaths were sedation-related. A more recent study concluded that propofol sedation is associated with a 13 % increase in all complications in patients undergoing colonoscopy. Providing sedation for GI endoscopy is thus an area with many undisputed challenges, controversies, and even some conspiracy theories [5, 6]. …
Literature
1.
go back to reference Park S, Ahn JY, Ahn YE, et al. Two cases of cerebral air embolism that occurred during esophageal ballooning and endoscopic retrograde cholangiopancreatography. Clin Endosc. 2016;49:191.CrossRefPubMedPubMedCentral Park S, Ahn JY, Ahn YE, et al. Two cases of cerebral air embolism that occurred during esophageal ballooning and endoscopic retrograde cholangiopancreatography. Clin Endosc. 2016;49:191.CrossRefPubMedPubMedCentral
2.
go back to reference Mathew J, Parker C, Wang J. Pulseless electrical activity arrest due to air embolism during endoscopic retrograde cholangiopancreatography: a case report and review of the literature. BMJ Open Gastroenterol. 2015;2:e000046.CrossRefPubMedPubMedCentral Mathew J, Parker C, Wang J. Pulseless electrical activity arrest due to air embolism during endoscopic retrograde cholangiopancreatography: a case report and review of the literature. BMJ Open Gastroenterol. 2015;2:e000046.CrossRefPubMedPubMedCentral
3.
go back to reference Goudra B, Nuzat A, Singh PM, Gouda GB, Carlin A, Manjunath AK. Cardiac arrests in patients undergoing gastrointestinal endoscopy: a retrospective analysis of 73,029 procedures. Saudi J Gastroenterol Off J Saudi Gastroenterol Assoc. 2015;21:400–411.CrossRef Goudra B, Nuzat A, Singh PM, Gouda GB, Carlin A, Manjunath AK. Cardiac arrests in patients undergoing gastrointestinal endoscopy: a retrospective analysis of 73,029 procedures. Saudi J Gastroenterol Off J Saudi Gastroenterol Assoc. 2015;21:400–411.CrossRef
4.
go back to reference Metzner J, Posner KL, Domino KB. The risk and safety of anesthesia at remote locations: the US closed claims analysis. Curr Opin Anaesthesiol. 2009;22:502–508.CrossRefPubMed Metzner J, Posner KL, Domino KB. The risk and safety of anesthesia at remote locations: the US closed claims analysis. Curr Opin Anaesthesiol. 2009;22:502–508.CrossRefPubMed
7.
go back to reference Mizrahi M, Sengupta N, Pleskow DK, Chuttani R, Sawhney MS, Berzin TM. Minor anesthesia-related events during radiofrequency ablation for barrett’s esophagus are associated with an increased number of treatment sessions. Dig Dis Sci. (Epub ahead of print). doi:10.1007/s10620-016-4059-8. Mizrahi M, Sengupta N, Pleskow DK, Chuttani R, Sawhney MS, Berzin TM. Minor anesthesia-related events during radiofrequency ablation for barrett’s esophagus are associated with an increased number of treatment sessions. Dig Dis Sci. (Epub ahead of print). doi:10.​1007/​s10620-016-4059-8.
8.
go back to reference Coté GA, Hovis RM, Ansstas MA, et al. Incidence of sedation-related complications with propofol use during advanced endoscopic procedures. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2010;8:137–142. Coté GA, Hovis RM, Ansstas MA, et al. Incidence of sedation-related complications with propofol use during advanced endoscopic procedures. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2010;8:137–142.
12.
go back to reference Goudra B, Singh PM. ERCP: the unresolved question of endotracheal intubation. Dig Dis Sci. 2014;59:513–519.CrossRefPubMed Goudra B, Singh PM. ERCP: the unresolved question of endotracheal intubation. Dig Dis Sci. 2014;59:513–519.CrossRefPubMed
13.
go back to reference Goudra B, Singh PM, Gouda G, Borle A, Carlin A, Yadwad A. Propofol and non-propofol based sedation for outpatient colonoscopy-prospective comparison of depth of sedation using an EEG based SEDLine monitor. J Clin Monit Comput. 2015. doi:10.1007/s10877-015-9769-5.PubMed Goudra B, Singh PM, Gouda G, Borle A, Carlin A, Yadwad A. Propofol and non-propofol based sedation for outpatient colonoscopy-prospective comparison of depth of sedation using an EEG based SEDLine monitor. J Clin Monit Comput. 2015. doi:10.​1007/​s10877-015-9769-5.PubMed
15.
go back to reference Goudra B, Chandramouli M, Singh P, Sandur V. Goudra ventilating bite block to reduce hypoxemia during endoscopic retrograde cholangiopancreatography. Saudi J Anaesth. 2014;8:299.CrossRefPubMedPubMedCentral Goudra B, Chandramouli M, Singh P, Sandur V. Goudra ventilating bite block to reduce hypoxemia during endoscopic retrograde cholangiopancreatography. Saudi J Anaesth. 2014;8:299.CrossRefPubMedPubMedCentral
Metadata
Title
Providing Deep Sedation for Advanced Endoscopic Procedures: The Esthetics of Endoscopic Anesthetics
Authors
Basavana Goudra
Preet Mohinder Singh
Publication date
01-06-2016
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 6/2016
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-016-4157-7

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