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01-03-2009 | Original Paper

Brachial Artery Differential Characteristic Impedance: Contributions from Changes in Young’s Modulus and Diameter

Authors: Glen Atlas, John K-J. Li

Published in: Cardiovascular Engineering | Issue 1/2009

Abstract

This examination of brachial artery (BA) differential characteristic impedance, ΔZ _c, illustrates that changes in Z _c can occur from changes in either BA wall stiffness (Young’s modulus, E) and/or its diameter, D. Furthermore, we assessed how changes in both E and D combine in either an isolated, synergistic, or antagonistic manner to yield the net change in BA Z _c. The basis of this analysis is a partial differential equation which approximates ΔZ _c as a total differential. The effects on BA ΔZ _c of acetylcholine, atenolol, fenoldapine, nitroglycerin, hydrochlorothiazide and other medications are examined using data from previously published studies. Clinical situations which alter BA Z _c, such as congestive heart failure, hypertension, and hyperemia, are also analyzed. Results illustrate the usefulness of the present approach in differentiating how medications, hyperemia, and pathological conditions affect BA ΔZ _c by causing independent changes to E and/or D.

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Title: Brachial Artery Differential Characteristic Impedance: Contributions from Changes in Young’s Modulus and Diameter
Authors: Glen Atlas
John K-J. Li
Publication date: 01-03-2009
Publisher: Springer US
Published in: Cardiovascular Engineering / Issue 1/2009
Print ISSN: 1567-8822
Electronic ISSN: 1573-6806
DOI: https://doi.org/10.1007/s10558-009-9071-6

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Brachial Artery Differential Characteristic Impedance: Contributions from Changes in Young’s Modulus and Diameter

Abstract

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