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The International Journal of Cardiovascular Imaging

Published in:

01-08-2012 | Original Paper

Correlation of angiographic late loss with neointimal coverage of drug-eluting stent struts on follow-up optical coherence tomography

Authors: Byeong-Keuk Kim, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong

Published in: The International Journal of Cardiovascular Imaging | Issue 6/2012

Abstract

Minimal data have been published on the correlation between angiographic late loss (LL) and incomplete neointimal coverage of struts after drug-eluting stent (DES) implantation. Therefore, we evaluated the relationship between angiographic LL and the percentage of uncovered struts on follow-up optical coherence tomography (OCT) images, in all cross-sections of the lesions. From the OCT registry database, 219 lesions without restenosis after DES implantation were divided into tertiles based on angiographic LL: tertile I (LL ≤ 0.26 mm), tertile II (0.26 < LL < 0.59 mm), and tertile III (≥0.59 mm). Lesions with the percentage of uncovered struts in the highest quartile (≥75th percentile; >6.0%) were defined as highly uncovered; in an independent analysis, lesions without any uncovered strut(s) were defined as completely covered. Higher percentages of uncovered struts were observed in tertile I than in both tertile II and III (10.3 ± 12.8% vs. 4.2 ± 7.4% vs. 2.4 ± 5.1%, respectively; P < 0.001 for I vs. II and I vs. III). Angiographic LL correlated significantly with the percentage of uncovered struts on OCT (r = −0.340, P < 0.001). The best cut-off values of angiographic LL to predict highly uncovered and completely covered lesions were 0.29 mm (area under curves [AUC] = 0.723, P < 0.001) and 0.61 mm (AUC = 0.692, P < 0.001), respectively. Angiographic LL inversely and significantly correlated with the percentage of uncovered struts on OCT after DES implantation.

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Title: Correlation of angiographic late loss with neointimal coverage of drug-eluting stent struts on follow-up optical coherence tomography
Authors: Byeong-Keuk Kim
Jung-Sun Kim
Young-Guk Ko
Donghoon Choi
Yangsoo Jang
Myeong-Ki Hong
Publication date: 01-08-2012
Publisher: Springer Netherlands
Published in: The International Journal of Cardiovascular Imaging / Issue 6/2012
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI: https://doi.org/10.1007/s10554-011-9944-9

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Correlation of angiographic late loss with neointimal coverage of drug-eluting stent struts on follow-up optical coherence tomography

Abstract

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Abstract

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