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Published in: The International Journal of Cardiovascular Imaging 2/2012

01-02-2012 | Original Paper

Atherosclerotic pattern of coronary myocardial bridging assessed with CT coronary angiography

Authors: Ludovico La Grutta, Giuseppe Runza, Massimo Galia, Erica Maffei, Giuseppe Lo Re, Emanuele Grassedonio, Carlo Tedeschi, Filippo Cademartiri, Massimo Midiri

Published in: The International Journal of Cardiovascular Imaging | Issue 2/2012

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Abstract

The aim of our study was to evaluate the atherosclerotic pattern of patients with coronary myocardial bridging (MB) by means of CT Coronary Angiography (CT-CA). 254 consecutive patients (166 male, mean age 58.6 ± 10.3) who underwent 64-slice CT-CA according to current clinical indications were reviewed for the presence of MB and concomitant segmental atherosclerotic pattern. Coronary plaques were assessed in all patients enrolled. 73 patients (29%) presented single (90%) or multiple (10%) MB, frequently (93%) localized in the mid-distal left anterior descending artery. The MB segment was always free of atherosclerosis. Segments proximal to the MB presented: no atherosclerotic disease (n = 37), positive remodeling (n = 23), <50% (n = 14), or >50% stenoses (n = 7). Distal segments presented a different atherosclerosis pattern (P < 0.0001): absence of disease (n = 73), no significant lesions (n = 8). No significant differences were found between segments proximal to MB and proximal coronary segments apart from left main trunk. Pattern of atherosclerotic lesions located in segments 6 and 7 significantly differs between patients with MB and patients without MB (P < 0.05). CT-CA is a reliable method to non-invasively demonstrate MB and related atherosclerotic pattern. CT-CA provides new insight regarding atherosclerosis distribution in segments close to MB.
Literature
1.
go back to reference Mohlenkamp S, Hort W, Ge J, Erbel R (2002) Update on myocardial bridging. Circulation 106:2616–2622PubMedCrossRef Mohlenkamp S, Hort W, Ge J, Erbel R (2002) Update on myocardial bridging. Circulation 106:2616–2622PubMedCrossRef
2.
go back to reference Rossi L, Dander B, Nidasio GP et al (1980) Myocardial bridges and ischemic heart disease. Eur Heart J 1:239–245PubMed Rossi L, Dander B, Nidasio GP et al (1980) Myocardial bridges and ischemic heart disease. Eur Heart J 1:239–245PubMed
3.
go back to reference Masuda T, Ishikawa Y, Akasaka Y, Itoh K, Kiguchi H, Ishii T (2001) The effect of myocardial bridging of the coronary artery on vasoactive agents and atherosclerosis localization. J Pathol 193:408–414PubMedCrossRef Masuda T, Ishikawa Y, Akasaka Y, Itoh K, Kiguchi H, Ishii T (2001) The effect of myocardial bridging of the coronary artery on vasoactive agents and atherosclerosis localization. J Pathol 193:408–414PubMedCrossRef
4.
go back to reference Ge J, Jeremias A, Rupp A et al (1999) New signs characteristic of myocardial bridging demonstrated by intracoronary ultrasound and Doppler. Eur Heart J 20:1707–1716PubMedCrossRef Ge J, Jeremias A, Rupp A et al (1999) New signs characteristic of myocardial bridging demonstrated by intracoronary ultrasound and Doppler. Eur Heart J 20:1707–1716PubMedCrossRef
5.
go back to reference Sanchez V, Zamorano J (1999) New approach to the diagnosis of myocardial bridging by intracoronary ultrasound and Doppler. Eur Heart J 20:1687–1688PubMedCrossRef Sanchez V, Zamorano J (1999) New approach to the diagnosis of myocardial bridging by intracoronary ultrasound and Doppler. Eur Heart J 20:1687–1688PubMedCrossRef
6.
go back to reference Schroeder S, Achenbach S, Bengel F et al (2008) Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology. Eur Heart J 29:531–556PubMedCrossRef Schroeder S, Achenbach S, Bengel F et al (2008) Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology. Eur Heart J 29:531–556PubMedCrossRef
7.
go back to reference Hendel RC, Patel MR, Kramer CM et al (2006) ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR 2006 appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging: a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group, American College of Radiology, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American Society of Nuclear Cardiology, North American Society for Cardiac Imaging, Society for Cardiovascular Angiography and Interventions, and Society of Interventional Radiology. J Am Coll Cardiol 48:1475–1497PubMedCrossRef Hendel RC, Patel MR, Kramer CM et al (2006) ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR 2006 appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging: a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group, American College of Radiology, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American Society of Nuclear Cardiology, North American Society for Cardiac Imaging, Society for Cardiovascular Angiography and Interventions, and Society of Interventional Radiology. J Am Coll Cardiol 48:1475–1497PubMedCrossRef
8.
go back to reference Kantarci M, Duran C, Durur I et al (2006) Detection of myocardial bridging with ECG-gated MDCT and multiplanar reconstruction. AJR Am J Roentgenol 186:S391–S394PubMedCrossRef Kantarci M, Duran C, Durur I et al (2006) Detection of myocardial bridging with ECG-gated MDCT and multiplanar reconstruction. AJR Am J Roentgenol 186:S391–S394PubMedCrossRef
9.
go back to reference De Rosa R, Sacco M, Tedeschi C et al (2008) Prevalence of coronary artery intramyocardial course in a large population of clinical patients detected by multislice computed tomography coronary angiography. Acta Radiol 49:895–901PubMedCrossRef De Rosa R, Sacco M, Tedeschi C et al (2008) Prevalence of coronary artery intramyocardial course in a large population of clinical patients detected by multislice computed tomography coronary angiography. Acta Radiol 49:895–901PubMedCrossRef
10.
go back to reference Canyigit M, Hazirolan T, Karcaaltincaba M et al (2009) Myocardial bridging as evaluated by 16 row MDCT. Eur J Radiol 69:156–164PubMedCrossRef Canyigit M, Hazirolan T, Karcaaltincaba M et al (2009) Myocardial bridging as evaluated by 16 row MDCT. Eur J Radiol 69:156–164PubMedCrossRef
11.
go back to reference Johansen C, Kirsch J, Araoz P, Williamson E (2008) Detection of myocardial bridging by 64-row computed tomography angiography of the coronaries. J Comput Assist Tomogr 32:448–451PubMedCrossRef Johansen C, Kirsch J, Araoz P, Williamson E (2008) Detection of myocardial bridging by 64-row computed tomography angiography of the coronaries. J Comput Assist Tomogr 32:448–451PubMedCrossRef
12.
go back to reference Kim PJ, Hur G, Kim SY et al (2009) Frequency of myocardial bridges and dynamic compression of epicardial coronary arteries: a comparison between computed tomography and invasive coronary angiography. Circulation 119:1408–1416PubMedCrossRef Kim PJ, Hur G, Kim SY et al (2009) Frequency of myocardial bridges and dynamic compression of epicardial coronary arteries: a comparison between computed tomography and invasive coronary angiography. Circulation 119:1408–1416PubMedCrossRef
13.
go back to reference Zeina AR, Odeh M, Blinder J, Rosenschein U, Barmeir E (2007) Myocardial bridge: evaluation on MDCT. AJR Am J Roentgenol 188:1069–1073PubMedCrossRef Zeina AR, Odeh M, Blinder J, Rosenschein U, Barmeir E (2007) Myocardial bridge: evaluation on MDCT. AJR Am J Roentgenol 188:1069–1073PubMedCrossRef
14.
go back to reference Lubarsky L, Gupta MP, Hecht HS (2007) Evaluation of myocardial bridging of the left anterior descending coronary artery by 64-slice multidetector computed tomographic angiography. Am J Cardiol 100:1081–1082PubMedCrossRef Lubarsky L, Gupta MP, Hecht HS (2007) Evaluation of myocardial bridging of the left anterior descending coronary artery by 64-slice multidetector computed tomographic angiography. Am J Cardiol 100:1081–1082PubMedCrossRef
15.
go back to reference Konen E, Goitein O, Sternik L, Eshet Y, Shemesh J, Segni ED (2007) The prevalence and anatomical patterns of intramuscular coronary arteries: a coronary computed tomography angiographic study. J Am Coll Cardiol 49:587–593PubMedCrossRef Konen E, Goitein O, Sternik L, Eshet Y, Shemesh J, Segni ED (2007) The prevalence and anatomical patterns of intramuscular coronary arteries: a coronary computed tomography angiographic study. J Am Coll Cardiol 49:587–593PubMedCrossRef
16.
go back to reference Cademartiri F, La Grutta L, Malagò R et al (2008) Prevalence of anatomical variants and coronary anomalies in 543 consecutive patients studied with 64-slice CT coronary angiography. Eur Radiol 18:781–791PubMedCrossRef Cademartiri F, La Grutta L, Malagò R et al (2008) Prevalence of anatomical variants and coronary anomalies in 543 consecutive patients studied with 64-slice CT coronary angiography. Eur Radiol 18:781–791PubMedCrossRef
17.
go back to reference Leschka S, Koepfli P, Husmann L et al (2008) Myocardial bridging: depiction rate and morphology at CT coronary angiography-comparison with conventional coronary angiography. Radiology 246:754–762PubMedCrossRef Leschka S, Koepfli P, Husmann L et al (2008) Myocardial bridging: depiction rate and morphology at CT coronary angiography-comparison with conventional coronary angiography. Radiology 246:754–762PubMedCrossRef
18.
go back to reference Jodocy D, Aglan I, Friedrich G et al (2010) Left anterior descending coronary artery myocardial bridging by multislice computed tomography: correlation with clinical findings. Eur J Radiol 73:89–95PubMedCrossRef Jodocy D, Aglan I, Friedrich G et al (2010) Left anterior descending coronary artery myocardial bridging by multislice computed tomography: correlation with clinical findings. Eur J Radiol 73:89–95PubMedCrossRef
19.
go back to reference La Grutta L, Runza G, Lo Re G et al (2009) Prevalence of myocardial bridging and correlation with coronary atherosclerosis studied with 64-slice CT coronary angiography. Radiol Med 114:1024–1036PubMedCrossRef La Grutta L, Runza G, Lo Re G et al (2009) Prevalence of myocardial bridging and correlation with coronary atherosclerosis studied with 64-slice CT coronary angiography. Radiol Med 114:1024–1036PubMedCrossRef
20.
go back to reference Budoff MJ, Cohen MC, Garcia MJ et al (2005) ACCF/AHA clinical competence statement on cardiac imaging with computed tomography and magnetic resonance. Circulation 112:598–617PubMedCrossRef Budoff MJ, Cohen MC, Garcia MJ et al (2005) ACCF/AHA clinical competence statement on cardiac imaging with computed tomography and magnetic resonance. Circulation 112:598–617PubMedCrossRef
21.
go back to reference Austen WG, Edwards JE, Frye RL et al (1975) A reporting system on patients evaluated for coronary artery disease: report of the ad hoc committee for grading of coronary artery disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51:5–40PubMed Austen WG, Edwards JE, Frye RL et al (1975) A reporting system on patients evaluated for coronary artery disease: report of the ad hoc committee for grading of coronary artery disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51:5–40PubMed
22.
go back to reference Mollet NR, Cademartiri F, Nieman K et al (2005) Noninvasive assessment of coronary plaque burden using multislice computed tomography. Am J Cardiol 95:1165–1169PubMedCrossRef Mollet NR, Cademartiri F, Nieman K et al (2005) Noninvasive assessment of coronary plaque burden using multislice computed tomography. Am J Cardiol 95:1165–1169PubMedCrossRef
23.
go back to reference Leschka S, Seitun S, Dettmer M et al (2010) Ex vivo evaluation of coronary atherosclerotic plaques: characterization with dual-source CT in comparison with histopathology. J Cardiovasc Comput Tomogr 4:301–308PubMedCrossRef Leschka S, Seitun S, Dettmer M et al (2010) Ex vivo evaluation of coronary atherosclerotic plaques: characterization with dual-source CT in comparison with histopathology. J Cardiovasc Comput Tomogr 4:301–308PubMedCrossRef
24.
go back to reference Ferreira AG Jr, Trotter SE, König B, Décourt LV, Fox K, Olsen EG (1991) Myocardial bridges: morphological and functional aspects. Br Heart J 66:364–367PubMedCrossRef Ferreira AG Jr, Trotter SE, König B, Décourt LV, Fox K, Olsen EG (1991) Myocardial bridges: morphological and functional aspects. Br Heart J 66:364–367PubMedCrossRef
25.
go back to reference Haager PK, Schwarz ER, vom Dahl J, Klues HG, Reffelmann T, Hanrath P (2000) Long term angiographic and clinical follow up in patients with stent implantation for symptomatic myocardial bridging. Heart 84:403–408PubMedCrossRef Haager PK, Schwarz ER, vom Dahl J, Klues HG, Reffelmann T, Hanrath P (2000) Long term angiographic and clinical follow up in patients with stent implantation for symptomatic myocardial bridging. Heart 84:403–408PubMedCrossRef
26.
go back to reference Ishikawa Y, Ishii T, Asuwa N, Masuda S (1997) Absence of atherosclerosis evolution in the coronary arterial segment covered by myocardial tissue in cholesterol-fed rabbits. Virchows Arch 430:163–171PubMedCrossRef Ishikawa Y, Ishii T, Asuwa N, Masuda S (1997) Absence of atherosclerosis evolution in the coronary arterial segment covered by myocardial tissue in cholesterol-fed rabbits. Virchows Arch 430:163–171PubMedCrossRef
27.
go back to reference Malek AM, Alper SL, Izumo S (1999) Hemodynamic shear stress and its role in atherosclerosis. J Am Med Assoc 282:2035–2042CrossRef Malek AM, Alper SL, Izumo S (1999) Hemodynamic shear stress and its role in atherosclerosis. J Am Med Assoc 282:2035–2042CrossRef
28.
go back to reference Klues HG, Schwarz ER, vom Dahl J et al (1997) Disturbed intracoronary hemodynamics in myocardial bridging. Early normalization by intracoronary stent placement. Circulation 96:2905–2913PubMed Klues HG, Schwarz ER, vom Dahl J et al (1997) Disturbed intracoronary hemodynamics in myocardial bridging. Early normalization by intracoronary stent placement. Circulation 96:2905–2913PubMed
29.
30.
go back to reference Valgimigli M, Rodriguez-Granillo GA, Garcia-Garcia HM et al (2007) Plaque composition in the left main stem mimics the distal but not the proximal tract of the left coronary artery influence of clinical presentation, length of the left main trunk, lipid profile, and systemic levels of Creactive protein. J Am Coll Cardiol 49:23–31PubMedCrossRef Valgimigli M, Rodriguez-Granillo GA, Garcia-Garcia HM et al (2007) Plaque composition in the left main stem mimics the distal but not the proximal tract of the left coronary artery influence of clinical presentation, length of the left main trunk, lipid profile, and systemic levels of Creactive protein. J Am Coll Cardiol 49:23–31PubMedCrossRef
31.
go back to reference Scheffel H, Alkadhi H, Plass A et al (2006) Accuracy of dualsource CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol 16:2739–2747PubMedCrossRef Scheffel H, Alkadhi H, Plass A et al (2006) Accuracy of dualsource CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol 16:2739–2747PubMedCrossRef
Metadata
Title
Atherosclerotic pattern of coronary myocardial bridging assessed with CT coronary angiography
Authors
Ludovico La Grutta
Giuseppe Runza
Massimo Galia
Erica Maffei
Giuseppe Lo Re
Emanuele Grassedonio
Carlo Tedeschi
Filippo Cademartiri
Massimo Midiri
Publication date
01-02-2012
Publisher
Springer Netherlands
Published in
The International Journal of Cardiovascular Imaging / Issue 2/2012
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-011-9817-2

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