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The International Journal of Cardiovascular Imaging
Published in: The International Journal of Cardiovascular Imaging 7/2009

Open Access 01-10-2009 | Original Paper

Right ventricular peak systolic longitudinal strain is a sensitive marker for right ventricular deterioration in adult patients with tetralogy of Fallot

Authors: Roderick W. C. Scherptong, Sjoerd A. Mollema, Nico A. Blom, Lucia J. M. Kroft, Albert de Roos, Hubert W. Vliegen, Ernst E. van der Wall, Jeroen J. Bax, Eduard R. Holman

Published in: The International Journal of Cardiovascular Imaging | Issue 7/2009

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Abstract

The aim of this study was to evaluate the feasibility of right ventricular (RV) longitudinal peak systolic strain (LPSS) assessment for the follow-up of adult patients with corrected tetralogy of Fallot (TOF). Adult patients (n = 18) with corrected TOF underwent echocardiography and CMR twice with a time interval of 4.2 ± 1.7 years. RV performance was derived from CMR, and included RV volumes and ejection fraction (EF). LPSS was calculated globally (GLPSS) and in the RV free wall (LPSS FW), with echocardiographic speckle-tracking strain-analysis. Baseline (G)LPSS values were compared between patients and healthy controls; the relation between (G)LPSS and CMR parameters was evaluated and the changes in (G)LPSS and CMR parameters during follow-up were compared. GLPSS and LPSS FW were significantly reduced in patients as compared to controls (−14.9 ± 0.7% vs. −21.6 ± 0.9% and −15.5 ± 0.9% vs. −22.7 ± 1.5%, P < 0.01). Moderate agreement between LPSS and CMR parameters was observed. RV EF remained unchanged during follow-up, whereas GLPSS and LPSS FW demonstrated a significant reduction. RVEF showed a 1% increase, whereas GLPSS decreased by 14%, and LPSS FW by 27%. RV LPSS is reduced in TOF patients as compared to controls; during follow-up RV EF remained unchanged whereas LPSS decreased suggesting that RV LPSS may be a sensitive marker to detect early deterioration in RV performance.
Literature
1.
Atik FA, Atik E, da Cunha CR et al (2004) Long-term results of correction of tetralogy of Fallot in adulthood. Eur J Cardiothorac Surg 25:250–255PubMedCrossRef
2.
van Straten A, Vliegen HW, Hazekamp MG et al (2005) Right ventricular function late after total repair of tetralogy of Fallot. Eur Radiol 15:702–707PubMedCrossRef
3.
Geva T, Sandweiss BM, Gauvreau K et al (2004) Factors associated with impaired clinical status in long-term survivors of tetralogy of Fallot repair evaluated by magnetic resonance imaging. J Am Coll Cardiol 43:1068–1074PubMedCrossRef
4.
Weidemann F, Eyskens B, Mertens L et al (2002) Quantification of regional right and left ventricular function by ultrasonic strain rate and strain indexes after surgical repair of tetralogy of Fallot. Am J Cardiol 90:133–138PubMedCrossRef
5.
Gondi S, Dokainish H (2007) Right ventricular tissue Doppler and strain imaging: ready for clinical use? Echocardiography 24:522–532PubMedCrossRef
6.
Perk G, Tunick PA, Kronzon I (2007) Non-Doppler two-dimensional strain imaging by echocardiography—from technical considerations to clinical applications. J Am Soc Echocardiogr 20:234–243PubMedCrossRef
7.
Leitman M, Lysyansky P, Sidenko S et al (2004) Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function. J Am Soc Echocardiogr 17:1021–1029PubMedCrossRef
8.
Reisner SA, Lysyansky P, Agmon Y et al (2004) Global longitudinal strain: a novel index of left ventricular systolic function. J Am Soc Echocardiogr 17:630–633PubMedCrossRef
9.
Vliegen HW, van Straten A, de Roos A et al (2002) Magnetic resonance imaging to assess the hemodynamic effects of pulmonary valve replacement in adults late after repair of tetralogy of fallot. Circulation 106:1703–1707PubMedCrossRef
10.
Oosterhof T, van Straten A, Vliegen HW et al (2007) Preoperative thresholds for pulmonary valve replacement in patients with corrected tetralogy of Fallot using cardiovascular magnetic resonance. Circulation 116:545–551PubMedCrossRef
11.
Niezen RA, Helbing WA, van der Wall EE et al (1996) Biventricular systolic function and mass studied with MR imaging in children with pulmonary regurgitation after repair for tetralogy of Fallot. Radiology 201:135–140PubMed
12.
Rebergen SA, Chin JG, Ottenkamp J et al (1993) Pulmonary regurgitation in the late postoperative follow-up of tetralogy of Fallot. Volumetric quantitation by nuclear magnetic resonance velocity mapping. Circulation 88:2257–2266PubMed
13.
Meadows J, Powell AJ, Geva T et al (2007) Cardiac magnetic resonance imaging correlates of exercise capacity in patients with surgically repaired tetralogy of Fallot. Am J Cardiol 100:1446–1450PubMedCrossRef
14.
Knauth AL, Gauvreau K, Powell AJ et al (2008) Ventricular size and function assessed by cardiac MRI predict major adverse clinical outcomes late after tetralogy of Fallot repair. Heart 94:211–216PubMedCrossRef
15.
Giardini A, Specchia S, Tacy TA et al (2007) Usefulness of cardiopulmonary exercise to predict long-term prognosis in adults with repaired tetralogy of Fallot. Am J Cardiol 99:1462–1467PubMedCrossRef
16.
Solarz DE, Witt SA, Glascock BJ et al (2004) Right ventricular strain rate and strain analysis in patients with repaired tetralogy of Fallot: possible interventricular septal compensation. J Am Soc Echocardiogr 17:338–344PubMedCrossRef
17.
Giannopoulos NM, Chatzis AC, Bobos DP et al (2004) Tetralogy of Fallot: influence of right ventricular outflow tract reconstruction on late outcome. Int J Cardiol 97(Suppl 1):87–90PubMedCrossRef
18.
Oosterhof T, Mulder BJ, Vliegen HW et al (2005) Corrected tetralogy of Fallot: delayed enhancement in right ventricular outflow tract. Radiology 237:868–871PubMedCrossRef
19.
Babu-Narayan SV, Kilner PJ, Li W et al (2006) Ventricular fibrosis suggested by cardiovascular magnetic resonance in adults with repaired tetralogy of fallot and its relationship to adverse markers of clinical outcome. Circulation 113:405–413PubMedCrossRef
Metadata
Title
Right ventricular peak systolic longitudinal strain is a sensitive marker for right ventricular deterioration in adult patients with tetralogy of Fallot
Authors
Roderick W. C. Scherptong
Sjoerd A. Mollema
Nico A. Blom
Lucia J. M. Kroft
Albert de Roos
Hubert W. Vliegen
Ernst E. van der Wall
Jeroen J. Bax
Eduard R. Holman
Publication date
01-10-2009
Publisher
Springer Netherlands
Published in
The International Journal of Cardiovascular Imaging / Issue 7/2009
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-009-9477-7

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