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Published in:

01-06-2008 | Original Paper

Vitamin D insufficiency among African-Americans in the southeastern United States: implications for cancer disparities (United States)

Authors: Kathleen M. Egan, Lisa B. Signorello, Heather M. Munro, Margaret K. Hargreaves, Bruce W. Hollis, William J. Blot

Published in: Cancer Causes & Control | Issue 5/2008

Abstract

Objective

To determine the prevalence and predictors of vitamin D insufficiency among black and white adult residents of the southern US.

Methods

A cross-sectional analysis of serum 25(OH)D levels using baseline blood samples from 395 Southern Community Cohort Study (SCCS) participants. Participants were African-American and white adults aged 40–79 who enrolled in the study from 2002–2004. We defined hypovitaminosis D as serum 25(OH)D levels ≤15 ng/ml.

Results

Hypovitaminosis D prevalence was 45% among blacks and 11% among whites. Vitamin D intake from diet and supplements was associated with modest increases in circulating 25(OH)D (0.5–0.7 ng/ml per 100 IU increment), but hypovitaminosis D was found for 32% of blacks with intake ≥400 IU/day. Body mass index (BMI) was a strong predictor of risk for hypovitaminosis D among black women (OR = 6.5, 95% CI 1.7–25.1 for BMI ≥30 kg/m² vs. 18–24.9 kg/m²). UVR exposure estimated by residential location was positively associated with 25(OH)D levels among all groups except white women.

Conclusions

Hypovitaminosis D was present in a substantial proportion of the African-American population studied, even in the South and among those meeting recommended dietary guidelines. Vitamin D should continue to be a studied target for ameliorating racial cancer disparities in the US.

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Title: Vitamin D insufficiency among African-Americans in the southeastern United States: implications for cancer disparities (United States)
Authors: Kathleen M. Egan
Lisa B. Signorello
Heather M. Munro
Margaret K. Hargreaves
Bruce W. Hollis
William J. Blot
Publication date: 01-06-2008
Publisher: Springer Netherlands
Published in: Cancer Causes & Control / Issue 5/2008
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI: https://doi.org/10.1007/s10552-008-9115-z

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