Skip to main content
Top
Published in: AIDS and Behavior 4/2013

01-05-2013 | Original Paper

A Systematic Review to Identify Challenges of Demonstrating Efficacy of HIV Behavioral Interventions for Gay, Bisexual, and Other Men Who Have Sex with Men (MSM)

Authors: Darrel H. Higa, Nicole Crepaz, Khiya J. Marshall, Linda Kay, H. Waverly Vosburgh, Pilgrim Spikes, Cynthia M. Lyles, David W. Purcell

Published in: AIDS and Behavior | Issue 4/2013

Login to get access

Abstract

Gay, bisexual, and other men who have sex with men (MSM) are disproportionately affected by HIV but few MSM-specific evidence-based interventions (EBIs) have been identified for this vulnerable group. We conducted a systematic review to identify reasons for the small number of EBIs for MSM. We also compared study, intervention and sample characteristics of EBIs versus non-EBIs to better understand the challenges of demonstrating efficacy evidence. Thirty-three MSM-specific studies were evaluated: Nine (27 %) were considered EBIs while 24 (73 %) were non-EBIs. Non-EBIs had multiple methodological limitations; the most common was not finding a significant positive effect. Compared to EBIs, non-EBIs were less likely to use peer intervention deliverers, include sexual communication in their interventions, and intervene at the community level. Incorporating characteristics associated with EBIs may strengthen behavioral interventions for MSM. More EBIs are needed for substance-using MSM, MSM of color, MSM residing in the south and MSM in couples.
Literature
2.
go back to reference Purcell DW, Johnson CH, Lansky A, et al. Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates. Open AIDS J. 2012;6:98–107.PubMedCrossRef Purcell DW, Johnson CH, Lansky A, et al. Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates. Open AIDS J. 2012;6:98–107.PubMedCrossRef
3.
go back to reference Prejean J, Song R, Hernandez A, et al. Estimated HIV incidence in the United States, 2006–2009. PLoS ONE. 2011;6(8):e17502.PubMedCrossRef Prejean J, Song R, Hernandez A, et al. Estimated HIV incidence in the United States, 2006–2009. PLoS ONE. 2011;6(8):e17502.PubMedCrossRef
4.
go back to reference Hall HI, Song R, Rhodes P, et al. Estimation of HIV incidence in the United States. JAMA. 2008;300(5):520–9.PubMedCrossRef Hall HI, Song R, Rhodes P, et al. Estimation of HIV incidence in the United States. JAMA. 2008;300(5):520–9.PubMedCrossRef
5.
go back to reference Hankins CA, de Zalduondo BO. Combination prevention: a deeper understanding of effective HIV prevention. AIDS. 2010;24(Suppl 4):S70–80.PubMedCrossRef Hankins CA, de Zalduondo BO. Combination prevention: a deeper understanding of effective HIV prevention. AIDS. 2010;24(Suppl 4):S70–80.PubMedCrossRef
6.
go back to reference Mansergh G, Higa D. HIV/AIDS in lesbian, gay, bisexual, and transgender communities. In: Hall JC, Hall BJ, Cockerell CJ, editors. HIV/AIDS in the post-HAART era: manifestations, treatment, and epidemiology. Shelton: People’s Medical Publishing House; 2011. p. 709–21. Mansergh G, Higa D. HIV/AIDS in lesbian, gay, bisexual, and transgender communities. In: Hall JC, Hall BJ, Cockerell CJ, editors. HIV/AIDS in the post-HAART era: manifestations, treatment, and epidemiology. Shelton: People’s Medical Publishing House; 2011. p. 709–21.
7.
go back to reference Kelly JA, Kalichman SC. Behavioral research in HIV/AIDS primary and secondary prevention: recent advances and future directions. J Consult Clin Psychol. 2002;70(3):626–39.PubMedCrossRef Kelly JA, Kalichman SC. Behavioral research in HIV/AIDS primary and secondary prevention: recent advances and future directions. J Consult Clin Psychol. 2002;70(3):626–39.PubMedCrossRef
8.
go back to reference Kegeles SM, Hays RB, Coates TJ. The Mpowerment Project: a community-level HIV prevention intervention for young gay men. Am J Public Health. 1996;86(8):1129–36.PubMedCrossRef Kegeles SM, Hays RB, Coates TJ. The Mpowerment Project: a community-level HIV prevention intervention for young gay men. Am J Public Health. 1996;86(8):1129–36.PubMedCrossRef
9.
go back to reference Kelly JA, St Lawrence JS, Stevenson LY, et al. Community AIDS/HIV risk reduction: the effects of endorsements by popular people in three cities. Am J Public Health. 1992;82(11):1483–9.PubMedCrossRef Kelly JA, St Lawrence JS, Stevenson LY, et al. Community AIDS/HIV risk reduction: the effects of endorsements by popular people in three cities. Am J Public Health. 1992;82(11):1483–9.PubMedCrossRef
10.
go back to reference Noar SM. Behavioral interventions to reduce HIV-related sexual risk behavior: review and synthesis of meta-analytic evidence. AIDS Behav. 2008;12(3):335–53.PubMedCrossRef Noar SM. Behavioral interventions to reduce HIV-related sexual risk behavior: review and synthesis of meta-analytic evidence. AIDS Behav. 2008;12(3):335–53.PubMedCrossRef
11.
go back to reference Herbst JH, Sherba RT, Crepaz N, et al. A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men. J Acquir Immune Defic Syndr. 2005;39(2):228–41.PubMed Herbst JH, Sherba RT, Crepaz N, et al. A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men. J Acquir Immune Defic Syndr. 2005;39(2):228–41.PubMed
12.
go back to reference Herbst JH, Beeker C, Mathew A, et al. The effectiveness of individual-, group- and community-level HIV behavioral risk-reduction interventions for adult men who have sex with men: a systematic review. Am J Prev Med. 2007;32(Suppl 4):S38–67.PubMedCrossRef Herbst JH, Beeker C, Mathew A, et al. The effectiveness of individual-, group- and community-level HIV behavioral risk-reduction interventions for adult men who have sex with men: a systematic review. Am J Prev Med. 2007;32(Suppl 4):S38–67.PubMedCrossRef
13.
go back to reference Johnson WD, Hedges LV, Ramirez G, et al. HIV prevention research for men who have sex with men: a systematic review and meta-analysis. J Acquir Immune Defic Syndr. 2002;30(Suppl 1):S118–29.PubMed Johnson WD, Hedges LV, Ramirez G, et al. HIV prevention research for men who have sex with men: a systematic review and meta-analysis. J Acquir Immune Defic Syndr. 2002;30(Suppl 1):S118–29.PubMed
14.
go back to reference Johnson WD, Holtgrave DR, McClellan WM, Flanders WD, Hill AN, Goodman M. HIV intervention research for men who have sex with men: a 7-year update. AIDS Educ Prev. 2005;17(6):568–89.PubMedCrossRef Johnson WD, Holtgrave DR, McClellan WM, Flanders WD, Hill AN, Goodman M. HIV intervention research for men who have sex with men: a 7-year update. AIDS Educ Prev. 2005;17(6):568–89.PubMedCrossRef
15.
go back to reference Johnson WD, Diaz RM, Flanders WD, et al. Behavioral interventions to reduce risk for sexual transmission of HIV among men who have sex with men. Cochrane Database Syst Rev. 2008;3:CD001230.PubMed Johnson WD, Diaz RM, Flanders WD, et al. Behavioral interventions to reduce risk for sexual transmission of HIV among men who have sex with men. Cochrane Database Syst Rev. 2008;3:CD001230.PubMed
16.
go back to reference Padian NS, McCoy SI, Balkus JE, Wasserheit JN. Weighing the gold in the gold standard: challenges in HIV prevention research. AIDS. 2010;24(5):621–35.PubMedCrossRef Padian NS, McCoy SI, Balkus JE, Wasserheit JN. Weighing the gold in the gold standard: challenges in HIV prevention research. AIDS. 2010;24(5):621–35.PubMedCrossRef
17.
18.
go back to reference Coates TJ, Richter L, Caceres C. Behavioural strategies to reduce HIV transmission: how to make them work better. Lancet. 2008;372(9639):669–84.PubMedCrossRef Coates TJ, Richter L, Caceres C. Behavioural strategies to reduce HIV transmission: how to make them work better. Lancet. 2008;372(9639):669–84.PubMedCrossRef
19.
go back to reference Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–99.PubMedCrossRef Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–99.PubMedCrossRef
20.
go back to reference de Wit JB, Aggleton P, Myers T, Crewe M. The rapidly changing paradigm of HIV prevention: time to strengthen social and behavioural approaches. Health Educ Res. 2011;26(3):381–92.PubMedCrossRef de Wit JB, Aggleton P, Myers T, Crewe M. The rapidly changing paradigm of HIV prevention: time to strengthen social and behavioural approaches. Health Educ Res. 2011;26(3):381–92.PubMedCrossRef
21.
go back to reference Mei S, Quax R, van de Vijver D, Zhu Y, Sloot PM. Increasing risk behaviour can outweigh the benefits of antiretroviral drug treatment on the HIV incidence among men-having-sex-with-men in Amsterdam. BMC Infect Dis. 2011;11:118.PubMedCrossRef Mei S, Quax R, van de Vijver D, Zhu Y, Sloot PM. Increasing risk behaviour can outweigh the benefits of antiretroviral drug treatment on the HIV incidence among men-having-sex-with-men in Amsterdam. BMC Infect Dis. 2011;11:118.PubMedCrossRef
23.
go back to reference Lyles CM, Crepaz N, Herbst JH, Kay LS. Evidence-based HIV behavioral prevention from the perspective of the CDC’s HIV/AIDS Prevention Research Synthesis Team. AIDS Educ Prev. 2006;18(4 Suppl A):21–31.PubMedCrossRef Lyles CM, Crepaz N, Herbst JH, Kay LS. Evidence-based HIV behavioral prevention from the perspective of the CDC’s HIV/AIDS Prevention Research Synthesis Team. AIDS Educ Prev. 2006;18(4 Suppl A):21–31.PubMedCrossRef
24.
go back to reference De Luca JB, Mullins MM, Lyles CM, Crepaz N, Kay L, Thadiparthi S. Developing a comprehensive search strategy for evidence-based systematic review. Evid Based Libr Inf Pract. 2011;3(1):3–32. De Luca JB, Mullins MM, Lyles CM, Crepaz N, Kay L, Thadiparthi S. Developing a comprehensive search strategy for evidence-based systematic review. Evid Based Libr Inf Pract. 2011;3(1):3–32.
25.
go back to reference Antoni MH, Cruess DG, Klimas N, et al. Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: effects on tranisitional naive T cells (CD4+ CD45RA+ CD29+). Am J Psychiat. 2002;159(1):143–4.PubMedCrossRef Antoni MH, Cruess DG, Klimas N, et al. Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: effects on tranisitional naive T cells (CD4+ CD45RA+ CD29+). Am J Psychiat. 2002;159(1):143–4.PubMedCrossRef
26.
go back to reference Carrico AW, Antoni MH, Pereira DB, et al. Cognitive behavioral stress management effects on mood, social support and a marker of antiviral immunity are maintained up to 1 year in HIV-infected gay men. Int J Behav Med. 2005;12(4):218–26.PubMedCrossRef Carrico AW, Antoni MH, Pereira DB, et al. Cognitive behavioral stress management effects on mood, social support and a marker of antiviral immunity are maintained up to 1 year in HIV-infected gay men. Int J Behav Med. 2005;12(4):218–26.PubMedCrossRef
27.
go back to reference Cosio D, Heckman TG, Anderson T, Heckman BD, Garske J, McCarthy J. Telephone-administered motivational interviewing to reduce risky sexual behavior in HIV-infected rural persons: a pilot randomized clinical trial. Sex Transm Dis. 2010;37(3):140–6.PubMedCrossRef Cosio D, Heckman TG, Anderson T, Heckman BD, Garske J, McCarthy J. Telephone-administered motivational interviewing to reduce risky sexual behavior in HIV-infected rural persons: a pilot randomized clinical trial. Sex Transm Dis. 2010;37(3):140–6.PubMedCrossRef
28.
go back to reference Gilbert P, Ciccarone D, Gansky SA, et al. Interactive “Video Doctor” counseling reduces drug and sexual risk behaviors among HIV-positive patients in diverse outpatient settings. PLoS ONE. 2008;3(4):e1988.PubMedCrossRef Gilbert P, Ciccarone D, Gansky SA, et al. Interactive “Video Doctor” counseling reduces drug and sexual risk behaviors among HIV-positive patients in diverse outpatient settings. PLoS ONE. 2008;3(4):e1988.PubMedCrossRef
29.
go back to reference Ironson G, Antoni MH, Schneiderman N, et al. Stress management and psychosocial predictors of disease course in HIV-1 infection. In: Goodkin K, Visser AP, editors. Psychoneuroimmunology: stress, mental disorders and health. Washington, DC: American Psychiatric; 2000. p. 317–56. Ironson G, Antoni MH, Schneiderman N, et al. Stress management and psychosocial predictors of disease course in HIV-1 infection. In: Goodkin K, Visser AP, editors. Psychoneuroimmunology: stress, mental disorders and health. Washington, DC: American Psychiatric; 2000. p. 317–56.
30.
go back to reference Kalichman SC, Rompa D, Cage M, et al. Effectiveness of an intervention to reduce HIV transmission risks in HIV-positive people. Am J Prev Med. 2001;21(2):84–92.PubMedCrossRef Kalichman SC, Rompa D, Cage M, et al. Effectiveness of an intervention to reduce HIV transmission risks in HIV-positive people. Am J Prev Med. 2001;21(2):84–92.PubMedCrossRef
31.
go back to reference Kelly JA, Murphy DA, Bahr GR, et al. Outcome of cognitive-behavioral and support group brief therapies for depressed, HIV-infected persons. Am J Psychiatry. 1993;150(11):1679–86.PubMed Kelly JA, Murphy DA, Bahr GR, et al. Outcome of cognitive-behavioral and support group brief therapies for depressed, HIV-infected persons. Am J Psychiatry. 1993;150(11):1679–86.PubMed
32.
go back to reference Lightfoot M, Tevendale H, Comulada WS, Rotheram-Borus MJ. Who benefited from an efficacious intervention for youth living with HIV: a moderator analysis. AIDS Behav. 2007;11(1):61–70.PubMedCrossRef Lightfoot M, Tevendale H, Comulada WS, Rotheram-Borus MJ. Who benefited from an efficacious intervention for youth living with HIV: a moderator analysis. AIDS Behav. 2007;11(1):61–70.PubMedCrossRef
33.
go back to reference Morin SF, Shade SB, Steward WT, et al. A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men. J Acquir Immune Defic Syndr. 2008;49(5):544–51.PubMedCrossRef Morin SF, Shade SB, Steward WT, et al. A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men. J Acquir Immune Defic Syndr. 2008;49(5):544–51.PubMedCrossRef
34.
go back to reference Richardson JL, Milam J, McCutchan A, et al. Effect of brief safer-sex counseling by medical providers to HIV-1 seropositive patients: a multi-clinic assessment. AIDS. 2004;18(8):1179–86.PubMedCrossRef Richardson JL, Milam J, McCutchan A, et al. Effect of brief safer-sex counseling by medical providers to HIV-1 seropositive patients: a multi-clinic assessment. AIDS. 2004;18(8):1179–86.PubMedCrossRef
35.
go back to reference Rotheram-Borus MJ, Swendeman D, Comulada WS, Weiss RE, Lee M, Lightfoot M. Prevention for substance-using HIV-positive young people: telephone and in-person delivery. J Acquir Immune Defic Syndr. 2004;37(Suppl 2):S68–77.PubMedCrossRef Rotheram-Borus MJ, Swendeman D, Comulada WS, Weiss RE, Lee M, Lightfoot M. Prevention for substance-using HIV-positive young people: telephone and in-person delivery. J Acquir Immune Defic Syndr. 2004;37(Suppl 2):S68–77.PubMedCrossRef
36.
go back to reference Kelly JA, Murphy DA, Sikkema KJ, et al. Randomised, controlled, community-level HIV-prevention intervention for sexual-risk behaviour among homosexual men in US cities. Community HIV Prevention Research Collaborative. Lancet. 1997;350(9090):1500–5.PubMedCrossRef Kelly JA, Murphy DA, Sikkema KJ, et al. Randomised, controlled, community-level HIV-prevention intervention for sexual-risk behaviour among homosexual men in US cities. Community HIV Prevention Research Collaborative. Lancet. 1997;350(9090):1500–5.PubMedCrossRef
37.
go back to reference Goldbaum GM, Johnson W, Wolitski RJ et al. Sexual behavior change among non-gay-identified men who have sex with men: response to a community-level intervention. Unpublished manuscript. Goldbaum GM, Johnson W, Wolitski RJ et al. Sexual behavior change among non-gay-identified men who have sex with men: response to a community-level intervention. Unpublished manuscript.
38.
go back to reference Picciano J, Roffman R, Kalichman S, Rutledge S, Berghuis J. A telephone based brief intervention using motivational enhancement to facilitate HIV risk reduction among MSM: a pilot study. AIDS Behav. 2001;5(3):251–62.CrossRef Picciano J, Roffman R, Kalichman S, Rutledge S, Berghuis J. A telephone based brief intervention using motivational enhancement to facilitate HIV risk reduction among MSM: a pilot study. AIDS Behav. 2001;5(3):251–62.CrossRef
39.
go back to reference Carpenter KM, Stoner SA, Mikko AN, Dhanak LP, Parsons JT. Efficacy of a web-based intervention to reduce sexual risk in men who have sex with men. AIDS Behav. 2010;14(3):549–57.PubMedCrossRef Carpenter KM, Stoner SA, Mikko AN, Dhanak LP, Parsons JT. Efficacy of a web-based intervention to reduce sexual risk in men who have sex with men. AIDS Behav. 2010;14(3):549–57.PubMedCrossRef
40.
go back to reference Rosser BR, Oakes JM, Konstan J, et al. Reducing HIV risk behavior of men who have sex with men through persuasive computing: results of the Men’s INTernet Study-II. AIDS. 2010;24(13):2099–107.PubMedCrossRef Rosser BR, Oakes JM, Konstan J, et al. Reducing HIV risk behavior of men who have sex with men through persuasive computing: results of the Men’s INTernet Study-II. AIDS. 2010;24(13):2099–107.PubMedCrossRef
41.
go back to reference Roffman RA, Picciano JF, Ryan R, et al. HIV-prevention group counseling delivered by telephone: an efficacy trial with gay and bisexual men. AIDS Behav. 1997;1(2):137–54.CrossRef Roffman RA, Picciano JF, Ryan R, et al. HIV-prevention group counseling delivered by telephone: an efficacy trial with gay and bisexual men. AIDS Behav. 1997;1(2):137–54.CrossRef
42.
go back to reference Coleman JD, Lindley LL, Annang L, Saunders RP, Gaddist B. Development of a framework for HIV/AIDS prevention programs in African American churches. AIDS Patient Care STDS. 2012;26(2):116–24.PubMedCrossRef Coleman JD, Lindley LL, Annang L, Saunders RP, Gaddist B. Development of a framework for HIV/AIDS prevention programs in African American churches. AIDS Patient Care STDS. 2012;26(2):116–24.PubMedCrossRef
43.
go back to reference Dilley JW, Woods WJ, Sabatino J, et al. Changing sexual behavior among gay male repeat testers for HIV: a randomized, controlled trial of a single-session intervention. J Acquir Immune Defic Syndr. 2002;30(2):177–86.PubMed Dilley JW, Woods WJ, Sabatino J, et al. Changing sexual behavior among gay male repeat testers for HIV: a randomized, controlled trial of a single-session intervention. J Acquir Immune Defic Syndr. 2002;30(2):177–86.PubMed
44.
go back to reference Dilley JW, Woods WJ, Loeb L, et al. Brief cognitive counseling with HIV testing to reduce sexual risk among men who have sex with men: results from a randomized controlled trial using paraprofessional counselors. J Acquir Immune Defic Syndr. 2007;44(5):569–77.PubMedCrossRef Dilley JW, Woods WJ, Loeb L, et al. Brief cognitive counseling with HIV testing to reduce sexual risk among men who have sex with men: results from a randomized controlled trial using paraprofessional counselors. J Acquir Immune Defic Syndr. 2007;44(5):569–77.PubMedCrossRef
45.
go back to reference Koblin B, Chesney M, Coates T. Effects of a behavioural intervention to reduce acquisition of HIV infection among men who have sex with men: the EXPLORE randomised controlled study. Lancet. 2004;364(9428):41–50.PubMedCrossRef Koblin B, Chesney M, Coates T. Effects of a behavioural intervention to reduce acquisition of HIV infection among men who have sex with men: the EXPLORE randomised controlled study. Lancet. 2004;364(9428):41–50.PubMedCrossRef
46.
go back to reference Mansergh G, Koblin BA, McKirnan DJ, et al. An intervention to reduce HIV risk behavior of substance-using men who have sex with men: a two-group randomized trial with a nonrandomized third group. PLoS Med. 2010;7(8):e1000329.PubMedCrossRef Mansergh G, Koblin BA, McKirnan DJ, et al. An intervention to reduce HIV risk behavior of substance-using men who have sex with men: a two-group randomized trial with a nonrandomized third group. PLoS Med. 2010;7(8):e1000329.PubMedCrossRef
47.
go back to reference Picciano JF, Roffman RA, Kalichman SC, Walker DD. Lowering obstacles to HIV prevention services: effects of a brief, telephone-based intervention using motivational enhancement therapy. Ann Behav Med. 2007;34(2):177–87.PubMedCrossRef Picciano JF, Roffman RA, Kalichman SC, Walker DD. Lowering obstacles to HIV prevention services: effects of a brief, telephone-based intervention using motivational enhancement therapy. Ann Behav Med. 2007;34(2):177–87.PubMedCrossRef
48.
go back to reference Read SJ, Miller LC, Appleby PR, et al. Socially optimized learning in a virtual environment: reducing risky sexual behavior among men who have sex with men. Health Commun Res. 2006;32(1):1–34.CrossRef Read SJ, Miller LC, Appleby PR, et al. Socially optimized learning in a virtual environment: reducing risky sexual behavior among men who have sex with men. Health Commun Res. 2006;32(1):1–34.CrossRef
49.
go back to reference Velasquez MM, von Sternberg K, Johnson DH, Green C, Carbonari JP, Parsons JT. Reducing sexual risk behaviors and alcohol use among HIV-positive men who have sex with men: a randomized clinical trial. J Consult Clin Psychol. 2009;77(4):657–67.PubMedCrossRef Velasquez MM, von Sternberg K, Johnson DH, Green C, Carbonari JP, Parsons JT. Reducing sexual risk behaviors and alcohol use among HIV-positive men who have sex with men: a randomized clinical trial. J Consult Clin Psychol. 2009;77(4):657–67.PubMedCrossRef
50.
go back to reference Wolitski RJ, Gomez CA, Parsons JT. Effects of a peer-led behavioral intervention to reduce HIV transmission and promote serostatus disclosure among HIV-seropositive gay and bisexual men. AIDS. 2005;19(Suppl 1):S99–109.PubMedCrossRef Wolitski RJ, Gomez CA, Parsons JT. Effects of a peer-led behavioral intervention to reduce HIV transmission and promote serostatus disclosure among HIV-seropositive gay and bisexual men. AIDS. 2005;19(Suppl 1):S99–109.PubMedCrossRef
51.
go back to reference Choi KH, Lew S, Vittinghoff E, Catania JA, Barrett DC, Coates TJ. The efficacy of brief group counseling in HIV risk reduction among homosexual Asian and Pacific Islander men. AIDS. 1996;10(1):81–7.PubMedCrossRef Choi KH, Lew S, Vittinghoff E, Catania JA, Barrett DC, Coates TJ. The efficacy of brief group counseling in HIV risk reduction among homosexual Asian and Pacific Islander men. AIDS. 1996;10(1):81–7.PubMedCrossRef
52.
go back to reference McKirnan DJ, Tolou-Shams M, Courtenay-Quirk C. The Treatment Advocacy Program: a randomized controlled trial of a peer-led safer sex intervention for HIV-infected men who have sex with men. J Consult Clin Psychol. 2010;78(6):952–63.PubMedCrossRef McKirnan DJ, Tolou-Shams M, Courtenay-Quirk C. The Treatment Advocacy Program: a randomized controlled trial of a peer-led safer sex intervention for HIV-infected men who have sex with men. J Consult Clin Psychol. 2010;78(6):952–63.PubMedCrossRef
53.
go back to reference Wilton L, Herbst JH, Coury-Doniger P, et al. Efficacy of an HIV/STI prevention intervention for black men who have sex with men: findings from the Many Men, Many Voices (3MV) project. AIDS Behav. 2009;13(3):532–44.PubMedCrossRef Wilton L, Herbst JH, Coury-Doniger P, et al. Efficacy of an HIV/STI prevention intervention for black men who have sex with men: findings from the Many Men, Many Voices (3MV) project. AIDS Behav. 2009;13(3):532–44.PubMedCrossRef
54.
go back to reference Carballo-Dieguez A, Dolezal C, Leu CS, et al. A randomized controlled trial to test an HIV-prevention intervention for Latino gay and bisexual men: lessons learned. AIDS Care. 2005;17(3):314–28.PubMedCrossRef Carballo-Dieguez A, Dolezal C, Leu CS, et al. A randomized controlled trial to test an HIV-prevention intervention for Latino gay and bisexual men: lessons learned. AIDS Care. 2005;17(3):314–28.PubMedCrossRef
55.
go back to reference Coates TJ, McKusick L, Kuno R, Stites DP. Stress reduction training changed number of sexual partners but not immune function in men with HIV. Am J Public Health. 1989;79(7):885–7.PubMedCrossRef Coates TJ, McKusick L, Kuno R, Stites DP. Stress reduction training changed number of sexual partners but not immune function in men with HIV. Am J Public Health. 1989;79(7):885–7.PubMedCrossRef
56.
go back to reference Kelly JA, St Lawrence JS, Hood HV, Brasfield TL. Behavioral intervention to reduce AIDS risk activities. J Consult Clin Psychol. 1989;57(1):60–7.PubMedCrossRef Kelly JA, St Lawrence JS, Hood HV, Brasfield TL. Behavioral intervention to reduce AIDS risk activities. J Consult Clin Psychol. 1989;57(1):60–7.PubMedCrossRef
57.
go back to reference Mausbach BT, Semple SJ, Strathdee SA, Zians J, Patterson TL. Efficacy of a behavioral intervention for increasing safer sex behaviors in HIV-positive MSM methamphetamine users: results from the EDGE study. Drug Alcohol Depend. 2007;87(2–3):249–57.PubMedCrossRef Mausbach BT, Semple SJ, Strathdee SA, Zians J, Patterson TL. Efficacy of a behavioral intervention for increasing safer sex behaviors in HIV-positive MSM methamphetamine users: results from the EDGE study. Drug Alcohol Depend. 2007;87(2–3):249–57.PubMedCrossRef
58.
go back to reference Menza TW, Jameson DR, Hughes JP, Colfax GN, Shoptaw S, Golden MR. Contingency management to reduce methamphetamine use and sexual risk among men who have sex with men: a randomized controlled trial. BMC Public Health. 2010;10:774.PubMedCrossRef Menza TW, Jameson DR, Hughes JP, Colfax GN, Shoptaw S, Golden MR. Contingency management to reduce methamphetamine use and sexual risk among men who have sex with men: a randomized controlled trial. BMC Public Health. 2010;10:774.PubMedCrossRef
59.
go back to reference Miller RL. Assisting gay men to maintain safer sex: an evaluation of an AIDS service organization’s safer sex maintenance program. AIDS Educ Prev. 1995;7(Suppl 5):48–63.PubMed Miller RL. Assisting gay men to maintain safer sex: an evaluation of an AIDS service organization’s safer sex maintenance program. AIDS Educ Prev. 1995;7(Suppl 5):48–63.PubMed
60.
go back to reference Morgenstern J, Bux DA Jr, Parsons J, Hagman BT, Wainberg M, Irwin T. Randomized trial to reduce club drug use and HIV risk behaviors among men who have sex with men. J Consult Clin Psychol. 2009;77(4):645–56.PubMedCrossRef Morgenstern J, Bux DA Jr, Parsons J, Hagman BT, Wainberg M, Irwin T. Randomized trial to reduce club drug use and HIV risk behaviors among men who have sex with men. J Consult Clin Psychol. 2009;77(4):645–56.PubMedCrossRef
61.
go back to reference Peterson JL, Coates TJ, Catania J, et al. Evaluation of an HIV risk reduction intervention among African–American homosexual and bisexual men. AIDS. 1996;10(3):319–25.PubMedCrossRef Peterson JL, Coates TJ, Catania J, et al. Evaluation of an HIV risk reduction intervention among African–American homosexual and bisexual men. AIDS. 1996;10(3):319–25.PubMedCrossRef
62.
go back to reference Roffman RA, Stephen RS, Curtin L, et al. Relapse prevention as an interventive model for HIV risk reduction in gay and bisexual men. AIDS Educ Prev. 1998;10(1):1–18.PubMed Roffman RA, Stephen RS, Curtin L, et al. Relapse prevention as an interventive model for HIV risk reduction in gay and bisexual men. AIDS Educ Prev. 1998;10(1):1–18.PubMed
63.
go back to reference Rosser BR, Hatfield LA, Miner MH, Ghiselli ME, Lee BR, Welles SL. Effects of a behavioral intervention to reduce serodiscordant unsafe sex among HIV positive men who have sex with men: the positive connections randomized controlled trial study. J Behav Med. 2010;33(2):147–58.PubMedCrossRef Rosser BR, Hatfield LA, Miner MH, Ghiselli ME, Lee BR, Welles SL. Effects of a behavioral intervention to reduce serodiscordant unsafe sex among HIV positive men who have sex with men: the positive connections randomized controlled trial study. J Behav Med. 2010;33(2):147–58.PubMedCrossRef
64.
go back to reference Serovich JM, Reed S, Grafsky EL, Andrist D. An intervention to assist men who have sex with men disclose their serostatus to casual sex partners: results from a pilot study. AIDS Educ Prev. 2009;21(3):207–19.PubMedCrossRef Serovich JM, Reed S, Grafsky EL, Andrist D. An intervention to assist men who have sex with men disclose their serostatus to casual sex partners: results from a pilot study. AIDS Educ Prev. 2009;21(3):207–19.PubMedCrossRef
65.
go back to reference Shoptaw S, Reback CJ, Peck JA, et al. Behavioral treatment approaches for methamphetamine dependence and HIV-related sexual risk behaviors among urban gay and bisexual men. Drug Alcohol Depend. 2005;78(2):125–34.PubMedCrossRef Shoptaw S, Reback CJ, Peck JA, et al. Behavioral treatment approaches for methamphetamine dependence and HIV-related sexual risk behaviors among urban gay and bisexual men. Drug Alcohol Depend. 2005;78(2):125–34.PubMedCrossRef
66.
go back to reference Stall RD, Paul JP, Barrett DC, Crosby GM, Bein E. An outcome evaluation to measure changes in sexual risk-taking among gay men undergoing substance use disorder treatment. J Stud Alcohol. 1999;60(6):837–45.PubMed Stall RD, Paul JP, Barrett DC, Crosby GM, Bein E. An outcome evaluation to measure changes in sexual risk-taking among gay men undergoing substance use disorder treatment. J Stud Alcohol. 1999;60(6):837–45.PubMed
67.
go back to reference Valdiserri RO, Lyter DW, Leviton LC, Callahan CM, Kingsley LA, Rinaldo CR. AIDS prevention in homosexual and bisexual men: results of a randomized trial evaluating two risk reduction interventions. AIDS. 1989;3(1):21–6.PubMed Valdiserri RO, Lyter DW, Leviton LC, Callahan CM, Kingsley LA, Rinaldo CR. AIDS prevention in homosexual and bisexual men: results of a randomized trial evaluating two risk reduction interventions. AIDS. 1989;3(1):21–6.PubMed
68.
go back to reference Williams JK, Wyatt GE, Rivkin I, Ramamurthi HC, Li X, Liu H. Risk reduction for HIV-positive African American and Latino men with histories of childhood sexual abuse. Arch Sex Behav. 2008;37(5):763–72.PubMedCrossRef Williams JK, Wyatt GE, Rivkin I, Ramamurthi HC, Li X, Liu H. Risk reduction for HIV-positive African American and Latino men with histories of childhood sexual abuse. Arch Sex Behav. 2008;37(5):763–72.PubMedCrossRef
69.
go back to reference Rosser BR, Bockting WO, Rugg DL, et al. A randomized controlled intervention trial of a sexual health approach to long-term HIV risk reduction for men who have sex with men: effects of the intervention on unsafe sexual behavior. AIDS Educ Prev. 2002;14(3 Suppl A):59–71.PubMedCrossRef Rosser BR, Bockting WO, Rugg DL, et al. A randomized controlled intervention trial of a sexual health approach to long-term HIV risk reduction for men who have sex with men: effects of the intervention on unsafe sexual behavior. AIDS Educ Prev. 2002;14(3 Suppl A):59–71.PubMedCrossRef
70.
go back to reference Stall R, Mills TC, Williamson J, et al. Association of co-occurring psychosocial health problems and increased vulnerability to HIV/AIDS among urban men who have sex with men. Am J Public Health. 2003;93(6):939–42.PubMedCrossRef Stall R, Mills TC, Williamson J, et al. Association of co-occurring psychosocial health problems and increased vulnerability to HIV/AIDS among urban men who have sex with men. Am J Public Health. 2003;93(6):939–42.PubMedCrossRef
71.
go back to reference Stall RD, Purcell DW. Intertwining epidemics: a review of research on substance use among men who have sex with men and its connection to the AIDS epidemic. AIDS Behav. 2000;4(2):181–92.CrossRef Stall RD, Purcell DW. Intertwining epidemics: a review of research on substance use among men who have sex with men and its connection to the AIDS epidemic. AIDS Behav. 2000;4(2):181–92.CrossRef
72.
go back to reference Ostrow DG, Stall R. Alcohol, tobacco, and drug use among gay and bisexual men. In: Wolitski RJ, Stall R, Valdiserri RO, editors. Unequal opportunity: health disparities affecting gay and bisexual men in the United States. New York: Oxford University Press; 2008. p. 121–58. Ostrow DG, Stall R. Alcohol, tobacco, and drug use among gay and bisexual men. In: Wolitski RJ, Stall R, Valdiserri RO, editors. Unequal opportunity: health disparities affecting gay and bisexual men in the United States. New York: Oxford University Press; 2008. p. 121–58.
73.
go back to reference Shoptaw S, Reback CJ. Methamphetamine use and infectious disease-related behaviors in men who have sex with men: implications for interventions. Addiction. 2007;102(Suppl 1):130–5.PubMedCrossRef Shoptaw S, Reback CJ. Methamphetamine use and infectious disease-related behaviors in men who have sex with men: implications for interventions. Addiction. 2007;102(Suppl 1):130–5.PubMedCrossRef
74.
go back to reference Chesney MA, Koblin BA, Barresi PJ, et al. An individually tailored intervention for HIV prevention: baseline data from the EXPLORE Study. Am J Public Health. 2003;93(6):933–8.PubMedCrossRef Chesney MA, Koblin BA, Barresi PJ, et al. An individually tailored intervention for HIV prevention: baseline data from the EXPLORE Study. Am J Public Health. 2003;93(6):933–8.PubMedCrossRef
75.
go back to reference Jenkins RA. Recruiting substance-using men who have sex with men into HIV prevention research: current status and future directions. AIDS Behav. 2012;16(6):1411–9.PubMedCrossRef Jenkins RA. Recruiting substance-using men who have sex with men into HIV prevention research: current status and future directions. AIDS Behav. 2012;16(6):1411–9.PubMedCrossRef
76.
go back to reference Hatfield LA, Ghiselli ME, Jacoby SM, et al. Methods for recruiting men of color who have sex with men in prevention-for-positives interventions. Prev Sci. 2010;11(1):56–66.PubMedCrossRef Hatfield LA, Ghiselli ME, Jacoby SM, et al. Methods for recruiting men of color who have sex with men in prevention-for-positives interventions. Prev Sci. 2010;11(1):56–66.PubMedCrossRef
77.
go back to reference Parsons JT, Vial AC, Starks TJ, Golub SA. Recruiting drug using men who have sex with men in behavioral intervention trials: a comparison of internet and field-based strategies. AIDS Behav. 2013;17:688–99. Parsons JT, Vial AC, Starks TJ, Golub SA. Recruiting drug using men who have sex with men in behavioral intervention trials: a comparison of internet and field-based strategies. AIDS Behav. 2013;17:688–99.
78.
go back to reference Higa D. Gay men’s brief sexual connections: settings, processes, meanings, and ethics. Dissertation. Seattle: University of Washington. 2008. Higa D. Gay men’s brief sexual connections: settings, processes, meanings, and ethics. Dissertation. Seattle: University of Washington. 2008.
79.
go back to reference Mizuno Y, Borkowf C, Millett GA, Bingham T, Ayala G, Stueve A. Homophobia and racism experienced by Latino men who have sex with men in the United States: correlates of exposure and associations with HIV risk behaviors. AIDS Behav. 2012;16(3):724–35.PubMedCrossRef Mizuno Y, Borkowf C, Millett GA, Bingham T, Ayala G, Stueve A. Homophobia and racism experienced by Latino men who have sex with men in the United States: correlates of exposure and associations with HIV risk behaviors. AIDS Behav. 2012;16(3):724–35.PubMedCrossRef
80.
go back to reference Van Devanter N, Duncan A, Burrell-Piggott T, et al. The influence of substance use, social sexual environment, psychosocial factors, and partner characteristics on high-risk sexual behavior among young black and Latino men who have sex with men living with HIV: a qualitative study. AIDS Patient Care STDS. 2011;25(2):113–21.CrossRef Van Devanter N, Duncan A, Burrell-Piggott T, et al. The influence of substance use, social sexual environment, psychosocial factors, and partner characteristics on high-risk sexual behavior among young black and Latino men who have sex with men living with HIV: a qualitative study. AIDS Patient Care STDS. 2011;25(2):113–21.CrossRef
81.
go back to reference Crepaz N, Lyles CM, Wolitski RJ, et al. Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials. AIDS. 2006;20(2):143–57.PubMedCrossRef Crepaz N, Lyles CM, Wolitski RJ, et al. Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials. AIDS. 2006;20(2):143–57.PubMedCrossRef
83.
go back to reference Bull SS, Lloyd L, Rietmeijer C, McFarlane M. Recruitment and retention of an online sample for an HIV prevention intervention targeting men who have sex with men: the Smart Sex Quest Project. AIDS Care. 2004;16(8):931–43.PubMedCrossRef Bull SS, Lloyd L, Rietmeijer C, McFarlane M. Recruitment and retention of an online sample for an HIV prevention intervention targeting men who have sex with men: the Smart Sex Quest Project. AIDS Care. 2004;16(8):931–43.PubMedCrossRef
84.
go back to reference Rhodes SD, Vissman AT, Stowers J, et al. A CBPR partnership increases HIV testing among men who have sex with men (MSM): outcome findings from a pilot test of the CyBER/testing internet intervention. Health Educ Behav. 2011;38(3):311–20.PubMedCrossRef Rhodes SD, Vissman AT, Stowers J, et al. A CBPR partnership increases HIV testing among men who have sex with men (MSM): outcome findings from a pilot test of the CyBER/testing internet intervention. Health Educ Behav. 2011;38(3):311–20.PubMedCrossRef
85.
go back to reference Chiasson MA, Shaw FS, Humberstone M, Hirshfield S, Hartel D. Increased HIV disclosure three months after an online video intervention for men who have sex with men (MSM). AIDS Care. 2009;21(9):1081–9.PubMedCrossRef Chiasson MA, Shaw FS, Humberstone M, Hirshfield S, Hartel D. Increased HIV disclosure three months after an online video intervention for men who have sex with men (MSM). AIDS Care. 2009;21(9):1081–9.PubMedCrossRef
86.
go back to reference Reback CJ, Ling D, Shoptaw S, Rohde J. Developing a text messaging risk reduction intervention for methamphetamine-using MSM: research note. Open AIDS J. 2010;4:116–22.PubMed Reback CJ, Ling D, Shoptaw S, Rohde J. Developing a text messaging risk reduction intervention for methamphetamine-using MSM: research note. Open AIDS J. 2010;4:116–22.PubMed
87.
go back to reference Bowen AM, Horvath K, Williams ML. A randomized control trial of internet-delivered HIV prevention targeting rural MSM. Health Educ Res. 2007;22(1):120–7.PubMedCrossRef Bowen AM, Horvath K, Williams ML. A randomized control trial of internet-delivered HIV prevention targeting rural MSM. Health Educ Res. 2007;22(1):120–7.PubMedCrossRef
88.
go back to reference El-Bassel N, Gilbert L, Witte S, Wu E, Hunt T, Remien RH. Couple-based HIV prevention in the United States: advantages, gaps, and future directions. J Acquir Immune Defic Syndr. 2010;55(Suppl 2):S98–101.PubMedCrossRef El-Bassel N, Gilbert L, Witte S, Wu E, Hunt T, Remien RH. Couple-based HIV prevention in the United States: advantages, gaps, and future directions. J Acquir Immune Defic Syndr. 2010;55(Suppl 2):S98–101.PubMedCrossRef
89.
go back to reference Sullivan PS, Salazar L, Buchbinder S, Sanchez TH. Estimating the proportion of HIV transmissions from main sex partners among men who have sex with men in five US cities. AIDS. 2009;23(9):1153–62.PubMedCrossRef Sullivan PS, Salazar L, Buchbinder S, Sanchez TH. Estimating the proportion of HIV transmissions from main sex partners among men who have sex with men in five US cities. AIDS. 2009;23(9):1153–62.PubMedCrossRef
90.
go back to reference Wu E, El-Bassel N, McVinney LD, et al. Feasibility and promise of a couple-based HIV/STI preventive intervention for methamphetamine-using, black men who have sex with men. AIDS Behav. 2011;15(8):1745–54.PubMedCrossRef Wu E, El-Bassel N, McVinney LD, et al. Feasibility and promise of a couple-based HIV/STI preventive intervention for methamphetamine-using, black men who have sex with men. AIDS Behav. 2011;15(8):1745–54.PubMedCrossRef
91.
go back to reference Elford J, Hart G. If HIV prevention works, why are rates of high-risk sexual behavior increasing among MSM? AIDS Educ Prev. 2003;15(4):294–308.PubMedCrossRef Elford J, Hart G. If HIV prevention works, why are rates of high-risk sexual behavior increasing among MSM? AIDS Educ Prev. 2003;15(4):294–308.PubMedCrossRef
92.
go back to reference Sullivan PS, Wolitski RJ. HIV infection among gay and bisexual men. In: Sullivan PS, Wolitski RJ, editors. Unequal opportunity: health disparities affecting gay and bisexual men in the United States. New York: Oxford Univeristy Press; 2008. p. 221–47. Sullivan PS, Wolitski RJ. HIV infection among gay and bisexual men. In: Sullivan PS, Wolitski RJ, editors. Unequal opportunity: health disparities affecting gay and bisexual men in the United States. New York: Oxford Univeristy Press; 2008. p. 221–47.
93.
go back to reference Chen HT. The bottom-up approach to integrative validity: a new perspective for program evaluation. Eval Program Plan. 2010;33(3):205–14.CrossRef Chen HT. The bottom-up approach to integrative validity: a new perspective for program evaluation. Eval Program Plan. 2010;33(3):205–14.CrossRef
Metadata
Title
A Systematic Review to Identify Challenges of Demonstrating Efficacy of HIV Behavioral Interventions for Gay, Bisexual, and Other Men Who Have Sex with Men (MSM)
Authors
Darrel H. Higa
Nicole Crepaz
Khiya J. Marshall
Linda Kay
H. Waverly Vosburgh
Pilgrim Spikes
Cynthia M. Lyles
David W. Purcell
Publication date
01-05-2013
Publisher
Springer US
Published in
AIDS and Behavior / Issue 4/2013
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-013-0418-z

Other articles of this Issue 4/2013

AIDS and Behavior 4/2013 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine