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01-03-2018 | Forefront Review

Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis

Authors: Takeshi Kezuka, Hitoshi Ishikawa

Published in: Japanese Journal of Ophthalmology | Issue 2/2018

Abstract

Anti-myelin-oligodendrocyte glycoprotein (MOG) antibody positive optic neuritis has been established as a new subset of optic neuropathy. Anti-MOG antibodies are usually measured by cell-based assay. Patients with anti-MOG antibody positive optic neuritis respond well to steroid therapy, and, while visual acuity outcomes are favorable, significant visual field defects remain. Furthermore, patients who are anti-MOG antibody positive have higher rates of recurrence compared to antibody negative patients. Based on these findings, anti-MOG antibody positive patients with optic neuritis have the characteristics of good visual outcomes, residual visual field defects, and high risk of recurrence. Tests for anti-MOG antibody are useful for the diagnosis and treatment of optic neuritis.

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Title: Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis
Authors: Takeshi Kezuka
Hitoshi Ishikawa
Publication date: 01-03-2018
Publisher: Springer Japan
Published in: Japanese Journal of Ophthalmology / Issue 2/2018
Print ISSN: 0021-5155
Electronic ISSN: 1613-2246
DOI: https://doi.org/10.1007/s10384-018-0561-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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