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01-11-2008 | Case Report

Successful Treatment of Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum with Radiation Therapy: Report of a Case

Authors: Marcus Foo, M.B.B.S., B.Med.Sci., Michael W. T. Chao, M.B.B.S., F.R.A.N.Z.C.R., Peter Gibbs, M.B.B.S., M.D., F.R.A.C.P., Michael Guiney, M.B.B.S., F.R.A.C.P., F.R.A.N.Z.C.R., Rodney Jacobs, M.Sc., F.R.A.C.S.

Published in: Diseases of the Colon & Rectum | Issue 11/2008

Abstract

We report a case of Stage IE mucosa-associated lymphoid tissue lymphoma arising in the rectum, which was successfully treated with radiotherapy. A 60-year-old man had several months of altered bowel habit with rectal bleeding and was found to have a large rectal tumor with no evidence of distant spread. Histologic studies showed this to be a mucosa-associated lymphoid tissue lymphoma. The patient received 45 Gy in 25 fractions with external beam radiotherapy during 5 weeks. The treatment was well tolerated and review at 41 months revealed no evidence of recurrence.

Isaacson P, Spencer J. Malignant lymphoma of mucosa-associated lymphoid tissue. Histopathology 1987;11:445–62.PubMedCrossRef

Matsumoto T, Iida M, Shimizu M. Regression of mucosa-associated lymphoid-tissue lymphoma of rectum after eradication of Helicobacter pylori. Lancet 1997;350:115–6.PubMedCrossRef

Gianni L, Tassinari D, Sartori S, Rinaldi P, Ravaioli A. Gastric, duodenal and rectal multifocal MALT lymphoma: the possible co-existence of two different cell populations. Eur J Cancer 1998;34:1640–1.PubMedCrossRef

Orita M, Yamashita K, Okino M, et al. A case of MALT (mucosa-associated lymphoid tissue) lymphoma occurring in the rectum. Hepatogastroenterology 1999;46:2352–4.PubMed

Isaacson P, Wright D. Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B cell lymphoma. Cancer 1983;52:1410–6.PubMedCrossRef

Yahalom J. MALT lymphomas: a radiation oncology viewpoint. Ann Hematol 2001;80:B100–5.PubMed

Shepherd N, Hall P, Coates P. Primary malignant lymphoma of the colon and rectum: a histopathological and immunohistochemical analysis of 45 cases with clinicopathological correlations. Histopathology 1988;12:235–52.PubMedCrossRef

Fan C, Changchien C, Wang J, et al. Primary colorectal lymphoma. Dis Colon Rectum 2000;43:1277–82.PubMedCrossRef

Takenaka R, Tomoda J, Sakata T, et al. Mucosa-associated lymphoid tissue lymphoma of the rectum that regressed spontaneously. J Gastro Hepatol 2000;15:331–5.CrossRef

10.

Inoue F, Chiba T. Regression of MALT lymphoma of the rectum after anti-H. pylori therapy in a patient negative for H. pylori. Gastroenterology 1999;117:514–5.PubMedCrossRef

11.

Hosaka S, Akamatsu T, Nakamura S, et al. Mucosa-associated lymphoid tissue (MALT) lymphoma of the rectum with chromosomal translocation of the t(11;18)(q21;q21) and an additional aberration of trisomy 3. Am J Gastroenterol 1999;94:1951–4.PubMedCrossRef

12.

Okamura S, Katsuhiko H, Satoh T. Regression of rectal mucosa-associated lymphoid tissue lymphoma unrelated to Helicobacter pylori. Ann Intern Med 2000;132:247.PubMed

13.

Gavioli M, Bagni A, Santacroce G, Piccagli I, Natalini G. Endorectal sonographic appearances of rectal MALT lymphoma, its response to therapy, and local recurrence. J Clin Ultrasound 2001;29:401–5.PubMedCrossRef

14.

Nakase H, Okazaki K, Ohana M, et al. The possible involvement of micro-organisms other than Helicobacter pylori in the development of rectal MALT lymphoma in H. pylori-negative patients. Endoscopy 2002;34:343–6.PubMedCrossRef

15.

Tsang R, Gospodarowicz M, Pintilie M, et al. Stage I and II MALT lymphoma: results of treatment with radiotherapy. Int J Radiation Oncology Biol Phys 2001;50:1258–64.

16.

Tsang R, Gospodarowicz M, Pintilie M, et al. Localised mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent clinical outcome. J Clin Oncol 2003;21:4157–64.PubMedCrossRef

17.

Hisabe T, Imamura K, Furukawa K, et al. Regression of CD5-positive and Helicobacter pylori-negative mucosa-associated lymphoid tissue lymphoma of the rectum after administration of antibiotics: report of a case. Dis Colon Rectum 2002;45:1267–70.PubMedCrossRef

18.

Rey J, Coso D, Ramuz O, et al. Low-grade rectal malt lymphoma occurring in a patient with chronic lymphocytic leukaemia. Br J Haematol 2002;119:1137–8.PubMedCrossRef

19.

Tanimoto A, Hamada T, Yamamoto T, Kimura S, Matsuki Y, Sasaguri Y. MALT lymphoma with extreme plasma cell differentiation of the rectum. Am J Gastroenterol 2002;97:1860–2.PubMedCrossRef

20.

Isomoto H, Yamasaki J, Kusakari C, Ohba K, Nishida Y, Kohno S. Simultaneous MALT lymphoma of stomach, duodenum and colon. Gastrointest Endosc 2003;58:251–2.PubMedCrossRef

21.

Navarra G, Adani G, Bardella E, Ascanelli S, Turini A, Pozza E. Primary rectal lymphoma as a cause of bowel obstruction. Report of a case. Tumori 2003;89:88–90.PubMed

22.

Tanaka S, Ohta T, Kaji E, Kosaka T, Murakami I. EMR of mucosa-associated lymphoid tissue lymphoma of the rectum. Gastrointest Endosc 2003;57:956–9.PubMedCrossRef

23.

Dohden K, Kaizaki Y, Hosokawa O, Hayashi H, Hattori M. Regression of rectal mucosa-associated lymphoid tissue lymphoma but persistence of Helicobacter pylori infection of gastric mucosa after administration of levofloxacin: report of a case. Dis Colon Rectum 2004;47:1544–6.PubMed

24.

Ahlawat S, Haddad N, Kanber Y, Cohen P, Ozdemirli M, Benjamin S. Primary mucosa-associated lymphoid tissue lymphoma occurring in the rectum. Gastrointest Endosc 2005;62:443–4.PubMedCrossRef

25.

Schechter N, Yahalom J. Low-grade MALT lymphoma of the stomach: a review of treatment options. Int J Radiation Oncology Biol Phys 2000;46:1093–103.

26.

Schechter N, Portlock C, Yahalom J. Treatment of mucosa-associated lymphoid tissue lymphoma of the stomach with radiation alone. J Clin Oncol 1998;16:1916–21.PubMed

27.

Zucca E, Conconi A, Pedrinis E, et al. Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue. Blood 2003;101:2489–95.PubMedCrossRef

28.

Armitage J, Weisenburger D. New approach to classifying non-Hodgkin’s lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin’s Lymphoma Classification Project. J Clin Oncol 1998;16:2780–95.PubMed

29.

Thieblemont C, Berger F, Dumontet C, et al. Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analysed. Blood 2000;95:802–6.PubMed

Title: Successful Treatment of Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum with Radiation Therapy: Report of a Case
Authors: Marcus Foo, M.B.B.S., B.Med.Sci.
Michael W. T. Chao, M.B.B.S., F.R.A.N.Z.C.R.
Peter Gibbs, M.B.B.S., M.D., F.R.A.C.P.
Michael Guiney, M.B.B.S., F.R.A.C.P., F.R.A.N.Z.C.R.
Rodney Jacobs, M.Sc., F.R.A.C.S.
Publication date: 01-11-2008
Publisher: Springer-Verlag
Published in: Diseases of the Colon & Rectum / Issue 11/2008
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI: https://doi.org/10.1007/s10350-008-9379-0

2024 ASCO Annual Meeting

Springer Medicine

Successful Treatment of Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum with Radiation Therapy: Report of a Case

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

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