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Published in: Diseases of the Colon & Rectum 2/2008

01-02-2008 | Original Contribution

Quality of Life after Low Anterior Resection and Temporary Loop Ileostomy

Authors: Akira Tsunoda, M.D., Ph.D., Yuko Tsunoda, M.D., Ph.D., Kazuhiro Narita, M.D., Ph.D., Makoto Watanabe, M.D., Ph.D., Kentaro Nakao, M.D., Ph.D., Mitsuo Kusano, M.D., Ph.D.

Published in: Diseases of the Colon & Rectum | Issue 2/2008

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Abstract

Purpose

Low anterior resection has become the operation of choice for mid rectal or low rectal cancer. A defunctioning stoma is routinely created at some centers to decrease the risk of leakage requiring surgical intervention. This study was designed to evaluate the quality of life in patients undergoing low anterior resection with a temporary ileostomy.

Methods

A prospective longitudinal study was conducted in 22 patients with rectal cancer who underwent low anterior resection with a loop ileostomy. Quality of life was assessed by using the European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-CR38 questionnaires. Twenty-five patients who underwent high anterior resection for rectosigmoid cancer were studied concurrently to evaluate the impact of major colorectal resection without a stoma.

Results

Patients’ scores on the quality of life questionnaires generally improved after high anterior resection; however, for patients who underwent low anterior resection, the scores for physical and role functioning before ileostomy closure were worse than the preoperative values. The scores on the quality of life questionnaires generally improved after ileostomy closure. Ileostomy closure required a short hospital stay and was rarely associated with complications.

Conclusion

Patients who underwent low anterior resection with ileostomy had significant reductions in physical and role functioning, which apparently improved after ileostomy closure. Similar declines in these quality of life variables were not found in patients who underwent high anterior resection. A temporary ileostomy should be created in selected patients with the highest risk of anastomotic leakage. Increased resources for not only surgical care but also for stoma therapy are necessary for patients who undergo low anterior resection with a temporary ileostomy.
Literature
1.
go back to reference Heald RJ. Total mesorectal excision is optimal surgery for rectal cancer: a Scandinavian consensus. Br J Surg 1995;82:1297–9.PubMedCrossRef Heald RJ. Total mesorectal excision is optimal surgery for rectal cancer: a Scandinavian consensus. Br J Surg 1995;82:1297–9.PubMedCrossRef
2.
go back to reference Nicholls RJ, Hall C. Treatment of non-disseminated cancer of the lower rectum. Br J Surg 1996;83:15–8.PubMedCrossRef Nicholls RJ, Hall C. Treatment of non-disseminated cancer of the lower rectum. Br J Surg 1996;83:15–8.PubMedCrossRef
3.
go back to reference Karanjia ND, Cordon AP, Holdsworth PL, Heald RJ. Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis. Br J Surg 1991;78:196–8.PubMedCrossRef Karanjia ND, Cordon AP, Holdsworth PL, Heald RJ. Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis. Br J Surg 1991;78:196–8.PubMedCrossRef
4.
go back to reference Arbman G, Nilsson, Hallbook O, Sjodahl R. Local recurrence following total mesorectal excision for rectal cancer. Br J Surg 1996;83:375–9.PubMedCrossRef Arbman G, Nilsson, Hallbook O, Sjodahl R. Local recurrence following total mesorectal excision for rectal cancer. Br J Surg 1996;83:375–9.PubMedCrossRef
5.
go back to reference Grabham JA, Moran BJ, Lane RH. Defunctioning colostomy for low anterior resection: a selective approach. Br J Surg 1995;82:1331–2.PubMedCrossRef Grabham JA, Moran BJ, Lane RH. Defunctioning colostomy for low anterior resection: a selective approach. Br J Surg 1995;82:1331–2.PubMedCrossRef
6.
go back to reference Poon RT, Chu KW, HO JW, Chan CW, Law WL, Wong J. Prospective evaluation of selective defunctioning stoma for low anterior resection with total mesorectal excision. World J Surg 1999;23:463–7.PubMedCrossRef Poon RT, Chu KW, HO JW, Chan CW, Law WL, Wong J. Prospective evaluation of selective defunctioning stoma for low anterior resection with total mesorectal excision. World J Surg 1999;23:463–7.PubMedCrossRef
7.
go back to reference Marusch F, Koch A, Schmidt U, et al. Value of a protective stoma in low anterior resection for rectal cancer. Dis Colon Rectum 2002;45:1164–71.PubMedCrossRef Marusch F, Koch A, Schmidt U, et al. Value of a protective stoma in low anterior resection for rectal cancer. Dis Colon Rectum 2002;45:1164–71.PubMedCrossRef
8.
go back to reference Getinger I, Marusch F, Steinert R, et al. Prospective defunctioning stoma in low anterior resection for rectal carcinoma. Br J Surg 2005;92:1137–42.CrossRef Getinger I, Marusch F, Steinert R, et al. Prospective defunctioning stoma in low anterior resection for rectal carcinoma. Br J Surg 2005;92:1137–42.CrossRef
9.
go back to reference O’Leary DP, Fide CJ, Foy C, Lucarotti ME. Quality of life after low anterior resection with total mesorectal excision and temporary loop ileostomy for rectal carcinoma. Br J Surg 2001;88:1216–20.PubMedCrossRef O’Leary DP, Fide CJ, Foy C, Lucarotti ME. Quality of life after low anterior resection with total mesorectal excision and temporary loop ileostomy for rectal carcinoma. Br J Surg 2001;88:1216–20.PubMedCrossRef
10.
go back to reference Camilleri-Brennan J, Steele RJ. Prospective analysis of quality of life after reversal of a defunctioning loop ileostomy. Colorectal Dis 2002;4:167–71.PubMedCrossRef Camilleri-Brennan J, Steele RJ. Prospective analysis of quality of life after reversal of a defunctioning loop ileostomy. Colorectal Dis 2002;4:167–71.PubMedCrossRef
11.
go back to reference Aaronson NK, Ahmedzai S, Bergman B, et al. European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993;85:365–76.PubMedCrossRef Aaronson NK, Ahmedzai S, Bergman B, et al. European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993;85:365–76.PubMedCrossRef
12.
go back to reference Sprangers MA, te Velde A, Aaronson NK. The construction and testing of the EORTC Colorectal Cancer-specific quality of life questionnaire module (QLQ-CR38). Eur J Cancer 1999;35:238–47.PubMedCrossRef Sprangers MA, te Velde A, Aaronson NK. The construction and testing of the EORTC Colorectal Cancer-specific quality of life questionnaire module (QLQ-CR38). Eur J Cancer 1999;35:238–47.PubMedCrossRef
13.
go back to reference Kobayashi K, Takeda F, Teramukai S, et al. A cross-validation of the European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30) for Japanese with lung cancer. Eur J Cancer 1998;34:810–5.PubMedCrossRef Kobayashi K, Takeda F, Teramukai S, et al. A cross-validation of the European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30) for Japanese with lung cancer. Eur J Cancer 1998;34:810–5.PubMedCrossRef
14.
go back to reference Tsunoda A, Yasuda N, Nakao K, et al. The construction and testing of the Japanese vergion of EORTC colorectal cancer-specific quality of life questionnaire module (EORTC QLQ-CR38) [in Japanese]. J Jpn Soc Coloproctol 2007;60:69–76.CrossRef Tsunoda A, Yasuda N, Nakao K, et al. The construction and testing of the Japanese vergion of EORTC colorectal cancer-specific quality of life questionnaire module (EORTC QLQ-CR38) [in Japanese]. J Jpn Soc Coloproctol 2007;60:69–76.CrossRef
15.
go back to reference EORTC Study Group on Quality of Life 1995. EortC QLQ-C30 scoring manual. Brussels: EORTC, 1995. EORTC Study Group on Quality of Life 1995. EortC QLQ-C30 scoring manual. Brussels: EORTC, 1995.
16.
go back to reference Tsunoda A, Nakao K, Hiratsuka K, Tsunoda Y, Kusano M. Prospective analysis of quality of life in the first year after colorectal cancer surgery. Acta Oncologica 2007;46:77–82.PubMedCrossRef Tsunoda A, Nakao K, Hiratsuka K, Tsunoda Y, Kusano M. Prospective analysis of quality of life in the first year after colorectal cancer surgery. Acta Oncologica 2007;46:77–82.PubMedCrossRef
17.
go back to reference Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol 1998;16:139–44.PubMed Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol 1998;16:139–44.PubMed
18.
go back to reference Dehni N, Schlegel RD, Cunningham C, Guiguet M, Tiret E, Parte R. Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis. Br J Surg 1998;85:1114–7.PubMedCrossRef Dehni N, Schlegel RD, Cunningham C, Guiguet M, Tiret E, Parte R. Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis. Br J Surg 1998;85:1114–7.PubMedCrossRef
Metadata
Title
Quality of Life after Low Anterior Resection and Temporary Loop Ileostomy
Authors
Akira Tsunoda, M.D., Ph.D.
Yuko Tsunoda, M.D., Ph.D.
Kazuhiro Narita, M.D., Ph.D.
Makoto Watanabe, M.D., Ph.D.
Kentaro Nakao, M.D., Ph.D.
Mitsuo Kusano, M.D., Ph.D.
Publication date
01-02-2008
Publisher
Springer-Verlag
Published in
Diseases of the Colon & Rectum / Issue 2/2008
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI
https://doi.org/10.1007/s10350-007-9101-7

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