Skip to main content
Top
Published in: Diseases of the Colon & Rectum 12/2006

01-12-2006

The Impact of Surgery for Colorectal Cancer on Quality of Life and Functional Status in the Elderly

Authors: Tara M. Mastracci, M.D., F.R.C.S.C., Samantha Hendren, M.D., Brenda O’Connor, B.Sc.N., Robin S. McLeod, M.D., F.R.C.S.C.

Published in: Diseases of the Colon & Rectum | Issue 12/2006

Login to get access

Purpose

Colorectal cancer is a common diagnosis in the elderly. Frequently concerns arise about outcomes after surgery, and little is known about postoperative quality of life in this older group after major bowel surgery. The objective of this study was to compare quality of life and functional status of elderly patients (older than aged 80 years) who have undergone surgery for colorectal cancer with a younger (younger than aged 70 years), procedure-matched control group.

Methods

Patients in the case (older than aged 80 years) and control groups (younger than aged 70 years) were identified from the colorectal cancer database at Mount Sinai Hospital, Toronto, Canada. All had treatment for colorectal cancer within the last five years. Patients were surveyed by mail using the European Organization for Research and Treatment of Cancer quality of life scales specific to cancer and colorectal cancer (EORTC-C30 and EORTC-CR38) and the Short Form-36. Student’s t-test was used to test differences.

Results

There were 29 patients in each of the groups. The current average ages were 83.2 (standard deviation = 2.79) years, and 67.7 (standard deviation = 5.1) years, respectively. The two groups scored similarly on the European Organization for Research and Treatment of Cancer quality of life scales in all domains except physical functioning, functional role, micturition, and stoma-related problems. Similarly, the mean scores of the Short Form-36 were similar with the exception of the vitality domain. Most patients did not require special assistance or alternate living arrangements after discharge from the hospital, and most patients seemed to be able to return to their preoperative level of functioning. However, stoma care was a greater concern to the elderly.

Conclusions

Elderly patients older than aged 80 years who are selected for surgery have a quality of life comparable to younger patients in most respects. Therefore, colorectal cancer surgery may be offered to the highly functioning elderly with the expectation of a good quality of life postoperatively.
Literature
3.
go back to reference Hosking, MP, Warner, MA, Lobdell, CM, Offord, KP, Melton, LJ 1989Outcomes of surgery in patients over 90 years of age and olderJAMA26119091915PubMedCrossRef Hosking, MP, Warner, MA, Lobdell, CM, Offord, KP, Melton, LJ 1989Outcomes of surgery in patients over 90 years of age and olderJAMA26119091915PubMedCrossRef
4.
go back to reference Avital, SA, Kashtan, H, Hadad, R, Werbin, N 1997Survival of colorectal carcinoma in the elderly. A prospective study of colorectal carcinoma and a five-year follow-upDis Colon Rectum40523529PubMedCrossRef Avital, SA, Kashtan, H, Hadad, R, Werbin, N 1997Survival of colorectal carcinoma in the elderly. A prospective study of colorectal carcinoma and a five-year follow-upDis Colon Rectum40523529PubMedCrossRef
5.
go back to reference Karnofsky, DA, Burchenal, JH 1949The clinical evaluation of chemotherapeutic agents in cancerMacleod, CM eds. Evaluation of chemotherapeutic agentsColumbia University PressNew York199205 Karnofsky, DA, Burchenal, JH 1949The clinical evaluation of chemotherapeutic agents in cancerMacleod, CM eds. Evaluation of chemotherapeutic agentsColumbia University PressNew York199205
6.
go back to reference Aaronson, NK, Ahmedzai, S, Bergman, B, et al. 1993The European Organization for Research and Treatment of Cancer QLQ-C30: A quality of life instrument for use in international clinical trials in oncologyJ Natl Cancer Inst85365376PubMed Aaronson, NK, Ahmedzai, S, Bergman, B,  et al. 1993The European Organization for Research and Treatment of Cancer QLQ-C30: A quality of life instrument for use in international clinical trials in oncologyJ Natl Cancer Inst85365376PubMed
7.
go back to reference Sprangers, MA, te Velde, A, Aaronson, NK 1999The construction and testing of the EORTC colorectal cancer-specific quality of life questionnaire moduleEur J Cancer35238248PubMedCrossRef Sprangers, MA, te Velde, A, Aaronson, NK 1999The construction and testing of the EORTC colorectal cancer-specific quality of life questionnaire moduleEur J Cancer35238248PubMedCrossRef
8.
go back to reference Hopman, WM, Towheed, T, Anastassiades, T, et al. 2000Canadian normative data for the SF-36 Health Survey. Canadian multicentre osteoporosis study research groupCMAJ163265271PubMed Hopman, WM, Towheed, T, Anastassiades, T,  et al. 2000Canadian normative data for the SF-36 Health Survey. Canadian multicentre osteoporosis study research groupCMAJ163265271PubMed
9.
go back to reference Udekwu, P, Gurkin, B, Oller, D, Lapio, L, Bourbina, J 2001Quality of life and functional level in elderly patients surviving surgical intensive careJ Am Coll Surg193245249PubMedCrossRef Udekwu, P, Gurkin, B, Oller, D, Lapio, L, Bourbina, J 2001Quality of life and functional level in elderly patients surviving surgical intensive careJ Am Coll Surg193245249PubMedCrossRef
10.
go back to reference Engoren, M, Arslanaina-Engoren, C, Steckel, D, Neihardt, J, Fenn-Buderer, N 2002Cost, outcome and functional status in octogenarians and septuagenarians after cardiac surgeryChest12213091315PubMedCrossRef Engoren, M, Arslanaina-Engoren, C, Steckel, D, Neihardt, J, Fenn-Buderer, N 2002Cost, outcome and functional status in octogenarians and septuagenarians after cardiac surgeryChest12213091315PubMedCrossRef
11.
go back to reference Ramsay, SD, Berry, K, Moinpour, C, Giedzinska, A, Andersen, MR 2002Quality of life in long-term survivors of colorectal cancerAm J Gastroenterol9712281234CrossRef Ramsay, SD, Berry, K, Moinpour, C, Giedzinska, A, Andersen, MR 2002Quality of life in long-term survivors of colorectal cancerAm J Gastroenterol9712281234CrossRef
12.
go back to reference Anthony, T, Jones, C, Antoine, J, Sivess-Franks, S, Turnage, R 2001The effect of treatment for colorectal cancer on long-term health-related quality of lifeAnn Surg Oncol84449PubMedCrossRef Anthony, T, Jones, C, Antoine, J, Sivess-Franks, S, Turnage, R 2001The effect of treatment for colorectal cancer on long-term health-related quality of lifeAnn Surg Oncol84449PubMedCrossRef
13.
go back to reference Saltzstein, SL, Behling, CA, Baergen, RN 1998Features of cancer in nonagenarians and centenariansJ Am Geriatr Soc46994998PubMed Saltzstein, SL, Behling, CA, Baergen, RN 1998Features of cancer in nonagenarians and centenariansJ Am Geriatr Soc46994998PubMed
14.
go back to reference Violi, V, Pietra, N, Grattarola, M, et al. 1998Curative surgery for colorectal cancer: long-term results and life expectancy in the elderlyDis Colon Rectum41291298PubMedCrossRef Violi, V, Pietra, N, Grattarola, M,  et al. 1998Curative surgery for colorectal cancer: long-term results and life expectancy in the elderlyDis Colon Rectum41291298PubMedCrossRef
15.
go back to reference Law, WL, Chu, KW, Tung, PH 2002Laparoscopic colorectal resection: a safe option for elderly patientsJ Am Coll Surg195768773PubMedCrossRef Law, WL, Chu, KW, Tung, PH 2002Laparoscopic colorectal resection: a safe option for elderly patientsJ Am Coll Surg195768773PubMedCrossRef
16.
go back to reference Morel, P, Egeli, RA, Wachtl, S, Rohner, A 1989Results of operative treatment of gastrointestinal tract tumors in patients over 80 years of ageArch Surg124662664PubMed Morel, P, Egeli, RA, Wachtl, S, Rohner, A 1989Results of operative treatment of gastrointestinal tract tumors in patients over 80 years of ageArch Surg124662664PubMed
Metadata
Title
The Impact of Surgery for Colorectal Cancer on Quality of Life and Functional Status in the Elderly
Authors
Tara M. Mastracci, M.D., F.R.C.S.C.
Samantha Hendren, M.D.
Brenda O’Connor, B.Sc.N.
Robin S. McLeod, M.D., F.R.C.S.C.
Publication date
01-12-2006
Publisher
Springer-Verlag
Published in
Diseases of the Colon & Rectum / Issue 12/2006
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI
https://doi.org/10.1007/s10350-006-0725-9

Other articles of this Issue 12/2006

Diseases of the Colon & Rectum 12/2006 Go to the issue

Announcement

Announcements