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Published in:

01-09-2006

Long-Term Functional and Quality of Life Outcomes After Coloanal Anastomosis for Distal Rectal Cancer

Authors: Imran Hassan, M.D., David W. Larson, M.D., Robert R. Cima, M.D., Janette U. Gaw, M.D., Heidi K. Chua, M.D., Dieter Hahnloser, M.D., John M. Stulak, M.D., Megan M. O’Byrne, M.A., Dirk R. Larson, M.S., Bruce G. Wolff, M.D., John H. Pemberton, M.D.

Published in: Diseases of the Colon & Rectum | Issue 9/2006

Purpose

This study was designed to evaluate the long-term functional and quality-of-life outcomes of patients after coloanal anastomosis for distal rectal cancer.

Methods

A total of 192 patients underwent coloanal anastomosis between 1982 and 2001 at two tertiary referral institutions. Standardized and validated questionnaires to assess functional and quality-of-life outcomes were mailed to 151 patients, of which 121 patients responded (median follow-up, 65 months).

Results

Patients receiving pelvic radiotherapy had more bowel function problems than patients who did not receive pelvic radiotherapy. No significant differences in relevant functional and quality-of-life outcomes were seen among patients who received preoperative or postoperative pelvic radiotherapy. Patients requiring permanent diversion as a result of complications of the surgery had decreased quality of life.

Conclusions

Coloanal anastomosis for distal rectal cancer has favorable long-term outcomes. Pelvic radiotherapy has an adverse effect on subsequent bowel function (whether given preoperatively or postoperatively) in patients who maintain intestinal continuity. Loss of intestinal continuity after a coloanal anastomosis is associated with diminished quality of life.

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Title: Long-Term Functional and Quality of Life Outcomes After Coloanal Anastomosis for Distal Rectal Cancer
Authors: Imran Hassan, M.D.
David W. Larson, M.D.
Robert R. Cima, M.D.
Janette U. Gaw, M.D.
Heidi K. Chua, M.D.
Dieter Hahnloser, M.D.
John M. Stulak, M.D.
Megan M. O’Byrne, M.A.
Dirk R. Larson, M.S.
Bruce G. Wolff, M.D.
John H. Pemberton, M.D.
Publication date: 01-09-2006
Publisher: Springer-Verlag
Published in: Diseases of the Colon & Rectum / Issue 9/2006
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI: https://doi.org/10.1007/s10350-006-0640-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Long-Term Functional and Quality of Life Outcomes After Coloanal Anastomosis for Distal Rectal Cancer

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Purpose

Methods

Results

Conclusions

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