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Published in: Magnetic Resonance Materials in Physics, Biology and Medicine 3/2015

01-06-2015 | Research Article

Free-breathing, zero-TE MR lung imaging

Authors: Fabio Gibiino, Laura Sacolick, Anne Menini, Luigi Landini, Florian Wiesinger

Published in: Magnetic Resonance Materials in Physics, Biology and Medicine | Issue 3/2015

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Abstract

Object

The investigation of three-dimensional radial, zero-echo time (TE) imaging for high-resolution, free-breathing magnetic resonance (MR) lung imaging using prospective and retrospective motion correction.

Materials and methods

Zero-TE was implemented similarly to the rotating-ultra-fast-imaging-sequence, providing 3D, isotropic, radial imaging with proton density contrast. Respiratory motion was addressed using prospective triggering (PT), prospective gating (PG) and retrospective gating (RG) with physiological signals obtained from a respiratory belt and interleaved pencil beam and DC navigators. The methods were demonstrated on four healthy volunteers at 3T.

Results

3D, radial zero-TE imaging with high imaging bandwidth and nominally zero echo-time enables efficient capture of short-lived signals from the lung parenchyma and the vessels. Compared to Cartesian encoding, unaccounted for free-breathing respiration resulted in only benign blurring artifacts confined to the origin of motion. Breath holding froze respiration but achieved only limited image resolution (~1.8 mm, 30 s). PT and PG obtained similar quality expiratory-phase images at 1.2 mm resolution in ~6 min scan time. RG allowed multi-phase imaging in ~15 min, derived from eight individually stored averages.

Conclusion

Zero-TE appears to be an attractive pulse sequence for 3D isotropic lung imaging. Prospective and retrospective approaches provide high-quality, free-breathing MR lung imaging within reasonable scan time.
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Metadata
Title
Free-breathing, zero-TE MR lung imaging
Authors
Fabio Gibiino
Laura Sacolick
Anne Menini
Luigi Landini
Florian Wiesinger
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Magnetic Resonance Materials in Physics, Biology and Medicine / Issue 3/2015
Print ISSN: 0968-5243
Electronic ISSN: 1352-8661
DOI
https://doi.org/10.1007/s10334-014-0459-y

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