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Magnetic Resonance Materials in Physics, Biology and Medicine
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine 4/2007

Open Access 01-10-2007 | Short Communication

In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T

Authors: Virginie Callot, Guillaume Duhamel, Patrick J. Cozzone

Published in: Magnetic Resonance Materials in Physics, Biology and Medicine | Issue 4/2007

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Abstract

Object To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI).
Materials and methods Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measurements.
Results Good quality images were obtained, with clear delineation of gray and white matter. Acquisition-time gain factor was up to 6 (vs. c-SE) and resolution up to 74 × 94 μm2 was achieved. T 1 and T 2 relaxation times were reliably measured.
Conclusion High-temporally and spatially resolved mouse spinal cord EPI imaging is feasible. This technique should greatly benefit to long acquisition-time experiments (diffusion imaging) and imaging of rapidly-evolving pathologies.
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Metadata
Title
In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T
Authors
Virginie Callot
Guillaume Duhamel
Patrick J. Cozzone
Publication date
01-10-2007
Publisher
Springer-Verlag
Published in
Magnetic Resonance Materials in Physics, Biology and Medicine / Issue 4/2007
Print ISSN: 0968-5243
Electronic ISSN: 1352-8661
DOI
https://doi.org/10.1007/s10334-007-0079-x

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