“Dysautonomia”: a plea for precision

Excerpt

The current state of development of medical knowledge, based in part on next generation sequencing and other advanced genomic approaches and the identification of signals involved in innate and adaptive immunity, has made imperative for the clinician to define disease phenotypes as accurately as possible. This is necessary both for appropriate interpretation of the increasing information provided by basic research and for its application to the evaluation and management of patients in an individualized manner. Physicians managing patients referred for autonomic disorders face unique challenges compared to those practicing other subspecialties. I will mention four challenges that, in my view, must be urgently considered and addressed. …