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01-06-2020 | Hypotension | Letter to the Editor

Mechanisms underlying unawareness of neurogenic orthostatic hypotension

Authors: Philip W. Tipton, William P. Cheshire

Published in: Clinical Autonomic Research | Issue 3/2020

Excerpt

Orthostatic hypotension (OH) is a common condition defined as a fall in blood pressure of ≥ 20 mmHg systolic or 10 mmHg diastolic within 3 min of assuming a standing position or head-up tilt [1]. Approximately one third of patients with persistent OH have neurogenic orthostatic hypotension (nOH), which is frequently associated with neurodegenerative diseases related to α-synuclein pathology and a key diagnostic discriminator among parkinsonian syndromes [2]. Screening for OH is also important for patient management. …

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van Gerpen J, Al-Shaikh RH, Tipton PW et al (2019) Progressive supranuclear palsy is not associated with neurogenic orthostatic hypotension. Neurology 93(14):e1339–e1347CrossRef

Arbogast SD, Alshekhlee AM, Hussain Z et al (2009) Hypotension unawareness in profound orthostatic hypotension. Am J Med 122(6):574–580CrossRef

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Gibbons CH, Schmidt P, Biagnnioni I et al (2017) The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension. J Neurol 264(8):1567–1582CrossRef

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Title: Mechanisms underlying unawareness of neurogenic orthostatic hypotension
Authors: Philip W. Tipton
William P. Cheshire
Publication date: 01-06-2020
Publisher: Springer Berlin Heidelberg
Keywords: Hypotension
Hypotension
Published in: Clinical Autonomic Research / Issue 3/2020
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI: https://doi.org/10.1007/s10286-020-00679-0

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Mechanisms underlying unawareness of neurogenic orthostatic hypotension

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