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Clinical Autonomic Research
Published in: Clinical Autonomic Research 1/2008

01-03-2008 | ARTICLE

The pathophysiology and diagnosis of orthostatic hypotension

Author: David Robertson, MD

Published in: Clinical Autonomic Research | Special Issue 1/2008

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Abstract

Orthostatic Hypotension (OH) is a common manifestation of blood pressure dysregulation. OH takes a heavy toll on quality of life. It has many potential etiologies, and many effects of aging can increase susceptibility to OH. Neurological disorders are especially likely to cause severe OH. In this brief review, the pathogenesis of OH is considered, particularly in terms of autonomic neuropathy, multiple system atrophy (MSA), pure autonomic failure, baroreflex failure, and dopamine beta hydroxylase deficiency. While OH is difficult to treat, its control greatly enhances the quality of life.
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Metadata
Title
The pathophysiology and diagnosis of orthostatic hypotension
Author
David Robertson, MD
Publication date
01-03-2008
Publisher
D. Steinkopff-Verlag
Published in
Clinical Autonomic Research / Issue Special Issue 1/2008
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-007-1004-0

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