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Published in: Journal of Digital Imaging 4/2013

01-08-2013

Combination of Radiological and Gray Level Co-occurrence Matrix Textural Features Used to Distinguish Solitary Pulmonary Nodules by Computed Tomography

Authors: Haifeng Wu, Tao Sun, Jingjing Wang, Xia Li, Wei Wang, Da Huo, Pingxin Lv, Wen He, Keyang Wang, Xiuhua Guo

Published in: Journal of Imaging Informatics in Medicine | Issue 4/2013

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Abstract

The objective of this study was to investigate the method of the combination of radiological and textural features for the differentiation of malignant from benign solitary pulmonary nodules by computed tomography. Features including 13 gray level co-occurrence matrix textural features and 12 radiological features were extracted from 2,117 CT slices, which came from 202 (116 malignant and 86 benign) patients. Lasso-type regularization to a nonlinear regression model was applied to select predictive features and a BP artificial neural network was used to build the diagnostic model. Eight radiological and two textural features were obtained after the Lasso-type regularization procedure. Twelve radiological features alone could reach an area under the ROC curve (AUC) of 0.84 in differentiating between malignant and benign lesions. The 10 selected characters improved the AUC to 0.91. The evaluation results showed that the method of selecting radiological and textural features appears to yield more effective in the distinction of malignant from benign solitary pulmonary nodules by computed tomography.
Literature
1.
go back to reference Matteis SD, Consonni D, Bertazzi PA: Exposure to occupational carcinogens and lung cancer risk. Evolution of epidemiological estimates of attributable fraction. Acta Biomed 79:34–42, 2008PubMed Matteis SD, Consonni D, Bertazzi PA: Exposure to occupational carcinogens and lung cancer risk. Evolution of epidemiological estimates of attributable fraction. Acta Biomed 79:34–42, 2008PubMed
2.
go back to reference Ries LAG, Harkins D, Krapcho M, et al: SEER Cancer Statistics Review, 1975–2003. National Cancer Institute, Bethesda, 2006 Ries LAG, Harkins D, Krapcho M, et al: SEER Cancer Statistics Review, 1975–2003. National Cancer Institute, Bethesda, 2006
4.
go back to reference Iwano S, Nakamura T, Kamioka Y, et al: Computer-aided differentiation of malignant from benign solitary pulmonary nodules imaged by high-resolution CT. Comput. Med. Imaging Graph 32:416–422, 2008PubMedCrossRef Iwano S, Nakamura T, Kamioka Y, et al: Computer-aided differentiation of malignant from benign solitary pulmonary nodules imaged by high-resolution CT. Comput. Med. Imaging Graph 32:416–422, 2008PubMedCrossRef
5.
go back to reference Ginneken BV, Armato III, SG, Hoop BD, et al: Comparing and combining algorithms for computer-aided detection of pulmonary nodules in computed tomography scans: the ANODE09 study. Medical Image Analysis 14:707–722, 2010PubMedCrossRef Ginneken BV, Armato III, SG, Hoop BD, et al: Comparing and combining algorithms for computer-aided detection of pulmonary nodules in computed tomography scans: the ANODE09 study. Medical Image Analysis 14:707–722, 2010PubMedCrossRef
6.
go back to reference Way TW, Sahiner B, Chan HP, et al: Computer-aided diagnosis of pulmonary nodules on CT scans: improvement of classification performance with nodule surface features. Medical Physics 36(7):3086–3098, 2008CrossRef Way TW, Sahiner B, Chan HP, et al: Computer-aided diagnosis of pulmonary nodules on CT scans: improvement of classification performance with nodule surface features. Medical Physics 36(7):3086–3098, 2008CrossRef
7.
go back to reference Yeh C, Lin CL, Wu MT, et al: A neural network-based diagnostic method for solitary pulmonary nodules. Neurocomputing 72:612–624, 2008CrossRef Yeh C, Lin CL, Wu MT, et al: A neural network-based diagnostic method for solitary pulmonary nodules. Neurocomputing 72:612–624, 2008CrossRef
8.
go back to reference McCarville MB, Lederman HM, Santana VM, et al: Distinguishing benign from malignant pulmonary nodules with helical chest CT in children with malignant solid tumors. Radiology 239(2):514–520, 2006PubMedCrossRef McCarville MB, Lederman HM, Santana VM, et al: Distinguishing benign from malignant pulmonary nodules with helical chest CT in children with malignant solid tumors. Radiology 239(2):514–520, 2006PubMedCrossRef
9.
go back to reference Avci E, Sengur A, Hanbay D: An optimum feature extraction method for texture classification. Expert Syst Appl 36:6036–6043, 2009CrossRef Avci E, Sengur A, Hanbay D: An optimum feature extraction method for texture classification. Expert Syst Appl 36:6036–6043, 2009CrossRef
10.
go back to reference Müller H, Michoux N, Bandon D, et al: A review of content-based image retrieval systems in medical applications—clinical benefits and future directions. International Journal of Medical Informatics 73:1–23, 2004PubMedCrossRef Müller H, Michoux N, Bandon D, et al: A review of content-based image retrieval systems in medical applications—clinical benefits and future directions. International Journal of Medical Informatics 73:1–23, 2004PubMedCrossRef
11.
go back to reference Ondimu S, Murase NH: Effect of probability-distance based Markovian texture extraction on discrimination in biological imaging. Comput Electron Agric 63(1):2–12, 2008CrossRef Ondimu S, Murase NH: Effect of probability-distance based Markovian texture extraction on discrimination in biological imaging. Comput Electron Agric 63(1):2–12, 2008CrossRef
12.
go back to reference Dettori L, Semler L: A comparison of wavelet, ridgelet, and curvelet-based texture classification algorithms in computed tomography. Computers in Biology and Medicine 37:486–498, 2009CrossRef Dettori L, Semler L: A comparison of wavelet, ridgelet, and curvelet-based texture classification algorithms in computed tomography. Computers in Biology and Medicine 37:486–498, 2009CrossRef
13.
go back to reference Erasmus JJ, Connolly JE, McAdams HP, et al: Solitary pulmonary nodules: part I. Morphologic evaluation for differentiation of benign and malignant lesions. Radiographics 20(1):43–58, 2000PubMed Erasmus JJ, Connolly JE, McAdams HP, et al: Solitary pulmonary nodules: part I. Morphologic evaluation for differentiation of benign and malignant lesions. Radiographics 20(1):43–58, 2000PubMed
14.
go back to reference Erasmus JJ, McAdams HP, Connolly JE: Solitary pulmonary nodules: part II. Evaluation of the indeterminate nodule. Radiographics 20(1):59–66, 2000PubMed Erasmus JJ, McAdams HP, Connolly JE: Solitary pulmonary nodules: part II. Evaluation of the indeterminate nodule. Radiographics 20(1):59–66, 2000PubMed
15.
go back to reference Nakamura K, Yoshida H, Engelmann R, et al: Computerized analysis of the likelihood of malignancy in solitary pulmonary nodules with use of artificial neural networks. Radiology 214:823–830, 2000PubMed Nakamura K, Yoshida H, Engelmann R, et al: Computerized analysis of the likelihood of malignancy in solitary pulmonary nodules with use of artificial neural networks. Radiology 214:823–830, 2000PubMed
16.
go back to reference Li F, Shusuke S, Hiroyuki A, et al: Malignant versus benign nodules at CT screening for lung cancer: comparison of thin-section ct findings. Radiology 233:793–798, 2004PubMedCrossRef Li F, Shusuke S, Hiroyuki A, et al: Malignant versus benign nodules at CT screening for lung cancer: comparison of thin-section ct findings. Radiology 233:793–798, 2004PubMedCrossRef
17.
go back to reference Wang H, Guo XH, Jia ZW, et al: Multilevel binomial logistic prediction model for malignant pulmonary nodules based on texture features of CT image. Eur J Radiol 74:124–129, 2010PubMedCrossRef Wang H, Guo XH, Jia ZW, et al: Multilevel binomial logistic prediction model for malignant pulmonary nodules based on texture features of CT image. Eur J Radiol 74:124–129, 2010PubMedCrossRef
18.
go back to reference Lee MC, Boroczky L, Sungur-Stasik K, et al: Computer-aided diagnosis of pulmonary nodules using a two-step approach for feature selection and classifier ensemble construction. Artificial Intelligence in Medicine 50:43–53, 2010PubMedCrossRef Lee MC, Boroczky L, Sungur-Stasik K, et al: Computer-aided diagnosis of pulmonary nodules using a two-step approach for feature selection and classifier ensemble construction. Artificial Intelligence in Medicine 50:43–53, 2010PubMedCrossRef
19.
go back to reference Zhu YJ, Tan YQ, Hua YQ, et al: Feature selection and performance evaluation of support vector machine (svm)-based classifier for differentiating benign and malignant pulmonary nodules by computed tomography. Journal of Digital Imaging 23(1):51–65, 2010PubMedCrossRef Zhu YJ, Tan YQ, Hua YQ, et al: Feature selection and performance evaluation of support vector machine (svm)-based classifier for differentiating benign and malignant pulmonary nodules by computed tomography. Journal of Digital Imaging 23(1):51–65, 2010PubMedCrossRef
20.
go back to reference Li Y, Chen KZ, Wang J: Development and validation of a clinical prediction model to estimate the probability of malignancy in solitary pulmonary nodules in Chinese people. Clinical Lung Cancer 12(5):313–319, 2011PubMedCrossRef Li Y, Chen KZ, Wang J: Development and validation of a clinical prediction model to estimate the probability of malignancy in solitary pulmonary nodules in Chinese people. Clinical Lung Cancer 12(5):313–319, 2011PubMedCrossRef
21.
go back to reference Zhang Y, Jin J, Qing XY, et al: LASSO based stimulus frequency recognition model for SSVEP BCIs. Biomedical Signal Processing and Control 7(2):104–111, 2011CrossRef Zhang Y, Jin J, Qing XY, et al: LASSO based stimulus frequency recognition model for SSVEP BCIs. Biomedical Signal Processing and Control 7(2):104–111, 2011CrossRef
22.
go back to reference Han SD, Tao WB, Wu XL: Texture segmentation using independent-scale component-wise Riemannian-covariance Gaussian mixture model in KL measure based multi-scale nonlinear structure tensor space. Pattern Recognition 44(3):503–518, 2011CrossRef Han SD, Tao WB, Wu XL: Texture segmentation using independent-scale component-wise Riemannian-covariance Gaussian mixture model in KL measure based multi-scale nonlinear structure tensor space. Pattern Recognition 44(3):503–518, 2011CrossRef
23.
go back to reference Zhang M, Zhu J, Djurdjanovic D, Ni J: A comparative study on the classification of engineering surfaces with dimension reduction and coefficient shrinkage methods. J Manuf Syst 25(3):209–220, 2007CrossRef Zhang M, Zhu J, Djurdjanovic D, Ni J: A comparative study on the classification of engineering surfaces with dimension reduction and coefficient shrinkage methods. J Manuf Syst 25(3):209–220, 2007CrossRef
24.
go back to reference Arora S, Acharya J, Verma A, et al: Multilevel thresholding for image segmentation through a fast statistical recursive algorithm. Pattern Recognit Lett 29:119–125, 2008CrossRef Arora S, Acharya J, Verma A, et al: Multilevel thresholding for image segmentation through a fast statistical recursive algorithm. Pattern Recognit Lett 29:119–125, 2008CrossRef
25.
go back to reference Taheri S, Ong SH, Chong VFH: Level-set segmentation of brain tumors using a threshold-based speed function. Image and Vision Computing 28:26–37, 2010CrossRef Taheri S, Ong SH, Chong VFH: Level-set segmentation of brain tumors using a threshold-based speed function. Image and Vision Computing 28:26–37, 2010CrossRef
26.
go back to reference Haralick RM, Shanmugam K, Dinstein I: Textural features for image classification. IEEE Trans Syst Man Cybernet 3:610–621, 1973CrossRef Haralick RM, Shanmugam K, Dinstein I: Textural features for image classification. IEEE Trans Syst Man Cybernet 3:610–621, 1973CrossRef
27.
go back to reference Haralick RM: Statistical and structural approaches to texture. Proc IEEE 67(5):786–804, 1979CrossRef Haralick RM: Statistical and structural approaches to texture. Proc IEEE 67(5):786–804, 1979CrossRef
28.
go back to reference Ribbing J, Nyberg J, Caster O, Jonsson EN: The lasso—a novel method for predictive covariate model building in nonlinear mixed effects models. J Pharmacokinet Pharmacodyn 34:485–517, 2007PubMedCrossRef Ribbing J, Nyberg J, Caster O, Jonsson EN: The lasso—a novel method for predictive covariate model building in nonlinear mixed effects models. J Pharmacokinet Pharmacodyn 34:485–517, 2007PubMedCrossRef
29.
go back to reference Zou H: The adaptive lasso and its oracle properties. J Am Stat Assoc 101:1418–1429, 2006CrossRef Zou H: The adaptive lasso and its oracle properties. J Am Stat Assoc 101:1418–1429, 2006CrossRef
30.
go back to reference Newell D, Nie K, Chen JH, et al: Selection of diagnostic features on breast MRI to differentiate between malignant and benign lesions using computer-aided diagnosis: differences in lesions presenting as mass and non-mass-like enhancement. Eur Radiol 20:771–781, 2010PubMedCrossRef Newell D, Nie K, Chen JH, et al: Selection of diagnostic features on breast MRI to differentiate between malignant and benign lesions using computer-aided diagnosis: differences in lesions presenting as mass and non-mass-like enhancement. Eur Radiol 20:771–781, 2010PubMedCrossRef
31.
go back to reference Markopoulos C, Kouskos E, Koufopoulos K: Use of artificial neural networks (computer analysis) in the diagnosis of microcalcifications on mammography. Eur J Radiol 39:60–65, 2001PubMedCrossRef Markopoulos C, Kouskos E, Koufopoulos K: Use of artificial neural networks (computer analysis) in the diagnosis of microcalcifications on mammography. Eur J Radiol 39:60–65, 2001PubMedCrossRef
32.
go back to reference Behzadi A, Ung Y, Lowe V, et al: The role of positron emission tomography in the management of non–small cell lung cancer. Can J Surg 52(3):235–242, 2009PubMed Behzadi A, Ung Y, Lowe V, et al: The role of positron emission tomography in the management of non–small cell lung cancer. Can J Surg 52(3):235–242, 2009PubMed
33.
go back to reference Gould MK, Ananth L, Barnett PG: A clinical model to estimate the pretest probability of lung cancer in patients with solitary pulmonary nodules. Chest 131(2):383–388, 2007PubMedCrossRef Gould MK, Ananth L, Barnett PG: A clinical model to estimate the pretest probability of lung cancer in patients with solitary pulmonary nodules. Chest 131(2):383–388, 2007PubMedCrossRef
34.
go back to reference Herder GJ, Tinteren HV, Golding RP, et al: Clinical prediction model to characterize pulmonary nodules. Chest 128:2490–2496, 2005PubMedCrossRef Herder GJ, Tinteren HV, Golding RP, et al: Clinical prediction model to characterize pulmonary nodules. Chest 128:2490–2496, 2005PubMedCrossRef
35.
go back to reference Newell D, Nie K, Chen JH: Selection of diagnostic features on breast MRI to differentiate between malignant and benign lesions using computer-aided diagnosis: differences in lesions presenting as mass and non-mass-like enhancement. Eur Radiol 20:771–781, 2010PubMedCrossRef Newell D, Nie K, Chen JH: Selection of diagnostic features on breast MRI to differentiate between malignant and benign lesions using computer-aided diagnosis: differences in lesions presenting as mass and non-mass-like enhancement. Eur Radiol 20:771–781, 2010PubMedCrossRef
Metadata
Title
Combination of Radiological and Gray Level Co-occurrence Matrix Textural Features Used to Distinguish Solitary Pulmonary Nodules by Computed Tomography
Authors
Haifeng Wu
Tao Sun
Jingjing Wang
Xia Li
Wei Wang
Da Huo
Pingxin Lv
Wen He
Keyang Wang
Xiuhua Guo
Publication date
01-08-2013
Publisher
Springer US
Published in
Journal of Imaging Informatics in Medicine / Issue 4/2013
Print ISSN: 2948-2925
Electronic ISSN: 2948-2933
DOI
https://doi.org/10.1007/s10278-012-9547-6

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