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Open Access 01-01-2017 | Original Article

Transanal total mesorectal excision (TaTME) for rectal cancer: effects on patient-reported quality of life and functional outcome

Authors: T. W. A. Koedam, G. H. van Ramshorst, C. L. Deijen, A. K. E. Elfrink, W. J. H. J. Meijerink, H. J. Bonjer, C. Sietses, J. B. Tuynman

Published in: Techniques in Coloproctology | Issue 1/2017

Abstract

Background

Transanal total mesorectal excision (TaTME) has rapidly become an important component of the treatment of rectal cancer surgery. Cohort studies have shown feasibility concerning procedure, specimen quality and morbidity. However, concerns exist about quality of life and ano(neo)rectal function. The aim of this study was to prospectively evaluate quality of life in patients following TaTME for rectal cancer with anastomosis.

Methods

Consecutive patients who underwent restorative TaTME surgery for rectal adenocarcinoma in an academic teaching center with tertiary referral function were evaluated. Validated questionnaires were prospectively collected. Quality of life was assessed by the EuroQol 5D (EQ-5D), European Organization for Research and Treatment of Cancer’s QLQ-C30 and QLQ-CR29 and low anterior resection syndrome (LARS) scale. Outcomes of the questionnaires at 1 and 6 months were compared with preoperative (baseline) values.

Results

Thirty patients after restorative TaTME for rectal cancer were included. Deterioration for all domains was mainly observed at 1 month after surgery compared to baseline, but most outcomes had returned to baseline at 6 months. Social function and anal pain remained significantly worse at 6 months. Major LARS (score >30) was 33% at 6 months after ileostomy closure. No end colostomies were required.

Conclusions

TaTME is associated with acceptable quality of life and functional outcome at 6 months after surgery comparable to published results after conventional laparoscopic low anterior resection.

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Title: Transanal total mesorectal excision (TaTME) for rectal cancer: effects on patient-reported quality of life and functional outcome
Authors: T. W. A. Koedam
G. H. van Ramshorst
C. L. Deijen
A. K. E. Elfrink
W. J. H. J. Meijerink
H. J. Bonjer
C. Sietses
J. B. Tuynman
Publication date: 01-01-2017
Publisher: Springer International Publishing
Published in: Techniques in Coloproctology / Issue 1/2017
Print ISSN: 1123-6337
Electronic ISSN: 1128-045X
DOI: https://doi.org/10.1007/s10151-016-1570-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Transanal total mesorectal excision (TaTME) for rectal cancer: effects on patient-reported quality of life and functional outcome

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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