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Published in: International Journal of Clinical Oncology 1/2012

01-02-2012 | Special Article

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer

Authors: Toshiaki Watanabe, Michio Itabashi, Yasuhiro Shimada, Shinji Tanaka, Yoshinori Ito, Yoichi Ajioka, Tetsuya Hamaguchi, Ichinosuke Hyodo, Masahiro Igarashi, Hideyuki Ishida, Megumi Ishiguro, Yukihide Kanemitsu, Norihiro Kokudo, Kei Muro, Atsushi Ochiai, Masahiko Oguchi, Yasuo Ohkura, Yutaka Saito, Yoshiharu Sakai, Hideki Ueno, Takayuki Yoshino, Takahiro Fujimori, Nobuo Koinuma, Takayuki Morita, Genichi Nishimura, Yuh Sakata, Keiichi Takahashi, Hiroya Takiuchi, Osamu Tsuruta, Toshiharu Yamaguchi, Masahiro Yoshida, Naohiko Yamaguchi, Kenjiro Kotake, Kenichi Sugihara, Japanese Society for Cancer of the Colon and Rectum

Published in: International Journal of Clinical Oncology | Issue 1/2012

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Abstract

Colorectal cancer is a major cause of death in Japan, where it accounts for the largest number of deaths from malignant neoplasms in women and the third largest number in men. Many new treatment methods have been developed over the last few decades. The Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer (JSCCR Guidelines 2010) have been prepared to show standard treatment strategies for colorectal cancer, to eliminate disparities among institutions in terms of treatment, to eliminate unnecessary treatment and insufficient treatment, and to deepen mutual understanding between health-care professionals and patients by making these Guidelines available to the general public. These Guidelines have been prepared by consensuses reached by the JSCCR Guideline Committee, based on a careful review of the evidence retrieved by literature searches and in view of the medical health insurance system and actual clinical practice settings in Japan. Therefore, these Guidelines can be used as a tool for treating colorectal cancer in actual clinical practice settings. More specifically, they can be used as a guide to obtaining informed consent from patients and choosing the method of treatment for each patient. As a result of the discussions held by the Guideline Committee, controversial issues were selected as Clinical Questions, and recommendations were made. Each recommendation is accompanied by a classification of the evidence and a classification of recommendation categories based on the consensus reached by the Guideline Committee members. Here we present the English version of the JSCCR Guidelines 2010.
Footnotes
1
In polypectomy, a snare is placed on the stalk of the lesion, and the lesion is electrocauterized using a high-frequency current. This method is mainly used for protruding lesions.
 
2
In EMR, the lesion is elevated through the local injection of a liquid such as physiological saline into the submucosa, and the lesion is electrocauterized just as in polypectomy. This method comprises the snare method [2] and EMR using a cap (EMRC). It is mainly used for superficial tumors and large sessile lesions.
 
3
In ESD, the lesion is elevated through the local injection of a liquid such as sodium hyaluronate solution into the submucosa of the perilesional area; then, circumferential incision of the mucosa surrounding the lesion and dissection of the submucosa are performed with a special knife [3]. ESD is mainly indicated for large tumors that cannot be resected by EMR.
 
4
FOLFOX is infusional 5-FU + LV + L-OHP.
 
5
CapeOX is capecitabine + L-OHP.
 
6
FOLFIRI is infusional 5-FU + LV + CPT-11.
 
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Metadata
Title
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer
Authors
Toshiaki Watanabe
Michio Itabashi
Yasuhiro Shimada
Shinji Tanaka
Yoshinori Ito
Yoichi Ajioka
Tetsuya Hamaguchi
Ichinosuke Hyodo
Masahiro Igarashi
Hideyuki Ishida
Megumi Ishiguro
Yukihide Kanemitsu
Norihiro Kokudo
Kei Muro
Atsushi Ochiai
Masahiko Oguchi
Yasuo Ohkura
Yutaka Saito
Yoshiharu Sakai
Hideki Ueno
Takayuki Yoshino
Takahiro Fujimori
Nobuo Koinuma
Takayuki Morita
Genichi Nishimura
Yuh Sakata
Keiichi Takahashi
Hiroya Takiuchi
Osamu Tsuruta
Toshiharu Yamaguchi
Masahiro Yoshida
Naohiko Yamaguchi
Kenjiro Kotake
Kenichi Sugihara
Japanese Society for Cancer of the Colon and Rectum
Publication date
01-02-2012
Publisher
Springer Japan
Published in
International Journal of Clinical Oncology / Issue 1/2012
Print ISSN: 1341-9625
Electronic ISSN: 1437-7772
DOI
https://doi.org/10.1007/s10147-011-0315-2

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