Skip to main content
Top
Published in: Emergency Radiology 6/2016

01-12-2016 | Original Article

Suboptimal CT pulmonary angiography in the emergency department: a retrospective analysis of outcomes in a large academic medical center

Authors: David D. B. Bates, Jaroslaw N. Tkacz, Christina A. LeBedis, Nagaraj Holalkere

Published in: Emergency Radiology | Issue 6/2016

Login to get access

Abstract

Optimal CT pulmonary angiography (CTPA) is a prerequisite for accurate diagnosis and management of suspected venous thromboembolic disease (VTE) in the emergency department (ED). However, a certain proportion of CTPA studies are diagnostically limited or non-diagnostic due to various technical causes. In this study, we analyze the incidence and cause of suboptimal CTPA studies in the ED and assess the need for additional imaging. Reports of 1444 consecutive CTPAs performed in an ED on adult patients over a 25-month period beginning November 30, 2011, were reviewed. The observed suboptimal CTPA rate was 4.2 % (60/1444). The most common causes of limited or non-diagnostic CTPA in the ED were related to timing of contrast bolus or IV infiltration (26/60, 43.4 %), respiratory motion (16/60, 26.7 %), multifactorial causes (10/60, 16.7 %), and patient motion (8/60, 13.3 %). Of the 60 studies included, only 7 patients (11.7 %) underwent additional diagnostic imaging during the same hospital visit for VTE, while 3 patients (5.0 %) underwent additional imaging for suspected VTE over the next 2 months. A total of 2/60 (3.4 %) patients had documented acute PE on additional imaging performed either on the same hospital visit or within 2 months. Regardless of the factors contributing to suboptimal CTPA, only a very small proportion of patients receive additional imaging to evaluate for VTE, either on the same visit or during the next 2 months (16.7 %, 10/60 patients). A small number (3.4 %) of these patients have documented acute PE within 2 months when additional imaging tests were performed.
Literature
1.
go back to reference Giuntini C, Di Ricco G, Marini C, Melillo E, Palla A (1995) Pulmonary embolism: epidemiology. Chest 107(1 Suppl):3S–9SCrossRefPubMed Giuntini C, Di Ricco G, Marini C, Melillo E, Palla A (1995) Pulmonary embolism: epidemiology. Chest 107(1 Suppl):3S–9SCrossRefPubMed
2.
go back to reference Calder KK, Herbert M, Henderson SO (2005) The mortality of untreated pulmonary embolism in emergency department patients. Ann Emerg Med 45(3):302–310CrossRefPubMed Calder KK, Herbert M, Henderson SO (2005) The mortality of untreated pulmonary embolism in emergency department patients. Ann Emerg Med 45(3):302–310CrossRefPubMed
4.
go back to reference Engelke C, Rummeny EJ, Marten K (2006) Pulmonary embolism at multi-detector row CT of chest: one-year survival of treated and untreated patients. Radiology 239(2):563–575CrossRefPubMed Engelke C, Rummeny EJ, Marten K (2006) Pulmonary embolism at multi-detector row CT of chest: one-year survival of treated and untreated patients. Radiology 239(2):563–575CrossRefPubMed
5.
go back to reference Polo Friz H, Molteni M, Del Sorbo D, et al. (2015) Mortality at 30 and 90 days in elderly patients with pulmonary embolism: a retrospective cohort study. Intern Emerg Med 10(4):431–436CrossRefPubMed Polo Friz H, Molteni M, Del Sorbo D, et al. (2015) Mortality at 30 and 90 days in elderly patients with pulmonary embolism: a retrospective cohort study. Intern Emerg Med 10(4):431–436CrossRefPubMed
6.
go back to reference Parikh N, Morris E, Babb J, et al. (2015) MDCT diagnosis of acute pulmonary embolism in the emergent setting. Emerg Radiol 22(4):379–384CrossRefPubMed Parikh N, Morris E, Babb J, et al. (2015) MDCT diagnosis of acute pulmonary embolism in the emergent setting. Emerg Radiol 22(4):379–384CrossRefPubMed
7.
go back to reference Mamlouk MD, van Sonnenberg E, Gosalia R, et al. (2010) Pulmonary embolism at CT angiography: implications for appropriateness, cost, and radiation exposure in 2003 patients. Radiology 256(2):625–632CrossRefPubMed Mamlouk MD, van Sonnenberg E, Gosalia R, et al. (2010) Pulmonary embolism at CT angiography: implications for appropriateness, cost, and radiation exposure in 2003 patients. Radiology 256(2):625–632CrossRefPubMed
8.
go back to reference Crichlow A, Cuker A, Mills AM (2012) Overuse of computed tomography pulmonary angiography in the evaluation of patients with suspected pulmonary embolism in the emergency department. Acad Emerg Med 19(11):1219–1226CrossRefPubMedPubMedCentral Crichlow A, Cuker A, Mills AM (2012) Overuse of computed tomography pulmonary angiography in the evaluation of patients with suspected pulmonary embolism in the emergency department. Acad Emerg Med 19(11):1219–1226CrossRefPubMedPubMedCentral
9.
go back to reference Molaee S, Ghanaati H, Safavi E, Foroumandi M, Peiman S (2015) Computed tomography pulmonary angiography for evaluation of patients with suspected pulmonary embolism: use or overuse. Iran J Radiol 12(3):e22383PubMedPubMedCentral Molaee S, Ghanaati H, Safavi E, Foroumandi M, Peiman S (2015) Computed tomography pulmonary angiography for evaluation of patients with suspected pulmonary embolism: use or overuse. Iran J Radiol 12(3):e22383PubMedPubMedCentral
10.
go back to reference Jones SE, Wittram C (2005) The indeterminate CT pulmonary angiogram: imaging characteristics and patient clinical outcome. Radiology 237(1):329–337CrossRefPubMed Jones SE, Wittram C (2005) The indeterminate CT pulmonary angiogram: imaging characteristics and patient clinical outcome. Radiology 237(1):329–337CrossRefPubMed
11.
go back to reference Mehta D, Barnett M, Zhou L, et al. (2014) Management and outcomes of single subsegmental pulmonary embolus: a retrospective audit at North Shore Hospital, New Zealand. Intern Med J 44(9):872–876CrossRefPubMed Mehta D, Barnett M, Zhou L, et al. (2014) Management and outcomes of single subsegmental pulmonary embolus: a retrospective audit at North Shore Hospital, New Zealand. Intern Med J 44(9):872–876CrossRefPubMed
12.
go back to reference Perrier A, Roy PM, Sanchez O, et al. (2005) Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 352(17):1760–1768CrossRefPubMed Perrier A, Roy PM, Sanchez O, et al. (2005) Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 352(17):1760–1768CrossRefPubMed
13.
go back to reference Stein PD, Fowler SE, Goodman LR, et al. (2006) Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 354(22):2317–2327CrossRefPubMed Stein PD, Fowler SE, Goodman LR, et al. (2006) Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 354(22):2317–2327CrossRefPubMed
14.
go back to reference van Belle A, Buller HR, Huisman MV, et al. (2006) Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA 295(2):172–179CrossRefPubMed van Belle A, Buller HR, Huisman MV, et al. (2006) Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA 295(2):172–179CrossRefPubMed
15.
go back to reference Carson JL, Kelley MA, Duff A, et al. (1992) The clinical course of pulmonary embolism. N Engl J Med 326(19):1240–1245CrossRefPubMed Carson JL, Kelley MA, Duff A, et al. (1992) The clinical course of pulmonary embolism. N Engl J Med 326(19):1240–1245CrossRefPubMed
16.
go back to reference Stein PD, Henry JW, Relyea B (1995) Untreated patients with pulmonary embolism. Outcome, clinical, and laboratory assessment. Chest 107(4):931–935CrossRefPubMed Stein PD, Henry JW, Relyea B (1995) Untreated patients with pulmonary embolism. Outcome, clinical, and laboratory assessment. Chest 107(4):931–935CrossRefPubMed
17.
go back to reference Gosselin MV, Rassner UA, Thieszen SL, Phillips J, Oki A (2004) Contrast dynamics during CT pulmonary angiogram: analysis of an inspiration associated artifact. J Thorac Imaging 19(1):1–7CrossRefPubMed Gosselin MV, Rassner UA, Thieszen SL, Phillips J, Oki A (2004) Contrast dynamics during CT pulmonary angiogram: analysis of an inspiration associated artifact. J Thorac Imaging 19(1):1–7CrossRefPubMed
18.
go back to reference Hayes SA, Soff GA, Zabor EC, Moskowitz CS, Liu CC, Ginsberg MS (2014) Clinical consequences of an indeterminate CT pulmonary angiogram in cancer patients. Clin Imaging 38(5):637–640CrossRefPubMedPubMedCentral Hayes SA, Soff GA, Zabor EC, Moskowitz CS, Liu CC, Ginsberg MS (2014) Clinical consequences of an indeterminate CT pulmonary angiogram in cancer patients. Clin Imaging 38(5):637–640CrossRefPubMedPubMedCentral
19.
go back to reference Schissler AJ, Rozenshtein A, Schluger NW, Einstein AJ (2015) National trends in emergency room diagnosis of pulmonary embolism, 2001-2010: a cross-sectional study. Respir Res 16:44CrossRefPubMedPubMedCentral Schissler AJ, Rozenshtein A, Schluger NW, Einstein AJ (2015) National trends in emergency room diagnosis of pulmonary embolism, 2001-2010: a cross-sectional study. Respir Res 16:44CrossRefPubMedPubMedCentral
20.
go back to reference Bettmann MA, Baginski SG, White RD, et al. (2012) ACR Appropriateness Criteria(R) acute chest pain—suspected pulmonary embolism. J Thorac Imaging 27(2):W28–W31CrossRefPubMed Bettmann MA, Baginski SG, White RD, et al. (2012) ACR Appropriateness Criteria(R) acute chest pain—suspected pulmonary embolism. J Thorac Imaging 27(2):W28–W31CrossRefPubMed
21.
go back to reference Cooper J (2015) Improving the diagnosis of pulmonary embolism in the emergency department. BMJ Qual Improv Rep 4(1) Cooper J (2015) Improving the diagnosis of pulmonary embolism in the emergency department. BMJ Qual Improv Rep 4(1)
22.
go back to reference Sodickson A, Baeyens PF, Andriole KP, et al. (2009) Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults. Radiology 251(1):175–184CrossRefPubMed Sodickson A, Baeyens PF, Andriole KP, et al. (2009) Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults. Radiology 251(1):175–184CrossRefPubMed
Metadata
Title
Suboptimal CT pulmonary angiography in the emergency department: a retrospective analysis of outcomes in a large academic medical center
Authors
David D. B. Bates
Jaroslaw N. Tkacz
Christina A. LeBedis
Nagaraj Holalkere
Publication date
01-12-2016
Publisher
Springer Berlin Heidelberg
Published in
Emergency Radiology / Issue 6/2016
Print ISSN: 1070-3004
Electronic ISSN: 1438-1435
DOI
https://doi.org/10.1007/s10140-016-1425-y

Other articles of this Issue 6/2016

Emergency Radiology 6/2016 Go to the issue

Acknowledgement to Reviewers

Recognition of our outstanding reviewers