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01-05-2017 | Review Article

Low-level laser therapy in the treatment of pressure ulcers: systematic review

Authors: Renata Saltiel Machado, Suane Viana, Graciele Sbruzzi

Published in: Lasers in Medical Science | Issue 4/2017

Abstract

The aim of this study was to evaluate the effects of low-level laser therapy (LLT) in pressure ulcers (PU) in humans through a systematic review of randomized studies. The search includes the databases MEDLINE, PEDro, Cochrane CENTRAL, and Lilacs, as well a manual search until May, 2016. This included randomized clinical trials of LLT compared with other interventions, different types of LLT, LLT placebo, or control in the treatment of PU. The outcomes evaluated were the ulcer area, healing rate, and overall healing rate. The risk of bias was evaluated using the tool of the Cochrane Collaboration, and the results were analyzed descriptively. From the 386 articles identified, only four studies were included, with two LLT used with single wavelength (1: 904 nm vs. control and 2: 940 nm vs. 808 nm vs. 658 nm vs. placebo) and two LLT used to probe cluster. One study compared to different single wavelengths showed a significant 71% reduction of the PU and an improved healing rate in which 47% of PU healed completely after 1 month of therapy with the use of LLT with a wavelength of 658 nm compared with other lengths. The other analyzed wavelengths were not significant in the assessed outcomes. Significant results were observed in the use of LLT with a 658 nm wavelength, and no evidence was found for use of wavelengths above that for the treatment of PU. Therefore, we also found no evidence in the laser used to probe the cluster.

Registration number: CRD42016036648.

Costa MP, Sturtz G, Costa FPP, Ferreira MC, Barros Filho TEP (2005) Epidemiologia e tratamento das úlceras de pressão: experiência de 77 casos. Acta Ortop Bras 13:124–133CrossRef

Blanes L, Duarte IS, Calil JA, Ferreira LM (2004) Avaliação clínica e epidemiológica das úlceras por pressão em pacientes internados no Hospital São Paulo. Rev Assoc Med Bras 50(2):182–187CrossRefPubMed

Lima ACB, Guerra DM (2011) Avaliação do custo do tratamento de úlceras por pressão em pacientes hospitalizados usando curativos industrializados. Cien Saude Colet 16:267–277CrossRefPubMed

Schue RM, Langemo DK (1998) Pressure ulcer prevalence and incidence and a modification of the Braden Scale for a rehabilitation unit. J Wound Ostomy Continence Nurs 25(1):36–43PubMed

Graves N, Birrell F, Whitby M (2005) Effect of pressure ulcers on length of hospital stay. Infect Control Hosp Epidemiol 26(3):293–297CrossRefPubMed

Qaseem A, Humphrey LL, Forciea MA, Starkey M et al (2015) Treatment of pressure ulcers: a clinical practice guideline from the American College of Physicians. Ann Intern Med 162:370–379CrossRefPubMed

Schubert V (2001) Effects of phototherapy on pressure ulcer healing in elderly patients after a falling trauma. A prospective, randomized, controlled study. Photodermatol Photoimmunol Photomed 17:32–38CrossRefPubMed

Iordanou P, Baltopoulos G, Giannakopoulou M, Bellou P, Ktenas E (2002) Effect of polarized light in the healing process of pressure ulcers. Int J Nurs Pract 8:49–55CrossRefPubMed

Assis GM, Moser ADL (2013) Laserterapia em úlceras por pressão: limitações para avaliação de resposta em pessoas com lesão medular. Texto Contexto Enferm 22(3):850–856CrossRef

10.

Gao X, Xing D (2009) Molecular mechanisms of cell proliferation induced by low power laser irradiation. J Biomed Sci 16:4CrossRefPubMedPubMedCentral

11.

Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M (2005) Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg 31(3):334–340CrossRefPubMed

12.

Mester E, Jaszagi-Nagy E (1973) The effects of laser radiation on wound healing and collagen synthesis. Stud Biophys 35:227–230

13.

Lanzafame RJ, Stadler I, Coleman J, Haerum B, Oskoui P, Whittaker M et al (2004) Temperature-controlled 830-nm low-level laser therapy of experimental pressure ulcers. Photomed Laser Surg 22(6):483CrossRefPubMed

14.

Taradaj J, Halski T, Kucharzewski M, Urbanek T, Halska U, Kucio C (2013) Effect of laser irradiation at different wavelengths (940, 808, and 658 nm) on pressure ulcer healing: results from a clinical study. Evid Based Complement Alternat Med 960240

15.

Lucas C, Gemert MJ, Haan RJ (2003) Efficacy of low-level laser therapy in the management of stage III decubitus ulcers: a prospective, observer-blinded multicentre randomised clinical trial. Lasers Med Sci 18:72–77. doi:10.1007/s10103-003-0259-5 CrossRefPubMed

16.

Nussbaum EL, Biemann I, Mustard B (1994) Comparison of ultrasound/ultraviolet-C and laser for treatment of pressure ulcers in patients with spinal cord injury. Phys Ther 74(9):812–823, discussion 24–5CrossRefPubMed

17.

Taly AB, Sivaraman Nair KP, Murali T, John A (2004) Efficacy of multiwavelength light therapy in the treatment of pressure ulcers in subjects with disorders of the spinal cord: a randomized double-blind controlled trial. Arch Phys Med Rehabil 85(10):1657–1661CrossRefPubMed

18.

Tatarunas AC, Matera JM, Dagli MLZ (1998) Estudo clínico e anatomopatológico da cicatrização cutânea no gato doméstico: utilização do laser de baixa potência GaAs (904 nm). Acta Cir Bras 13

19.

Kolari PJ (1985) Penetration of unfocused laser light into the skin. Arch Dermatol Res 277(4):342–344CrossRefPubMed

20.

Alves AN, Fernandes KP, Melo CA, Yamaguchi RY, Franca CM, Teixeira DF et al (2014) Modulating effect of low level-laser therapy on fibrosis in the repair process of the tibialis anterior muscle in rats. Lasers Med Sci 29(2):813–821CrossRefPubMed

21.

Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Rossi RP, Grosselli D et al (2009) Comparison between single-diode low-level laser therapy (LLLT) and LED multi-diode (cluster) therapy (LEDT) applications before high-intensity exercise. Photomed Laser Surg 27(4):617–623CrossRefPubMed

22.

Leal Junior ECP, Lopes-Martins RÁB, Rossi RP, De Marchi T, Baroni BM, de Godoi V et al (2009) Effect of cluster multi-diode light emitting diode therapy (LEDT) on exercise-induced skeletal muscle fatigue and skeletal muscle recovery in humans. Lasers Surg Med 41(8):572–577CrossRefPubMed

23.

Enwemeka CS (2009) Intricacies of dose in laser phototherapy for tissue repair and pain relief. Photomed Laser Surg 27(3):387–393CrossRefPubMed

24.

Huang YY, Chen AC, Carroll JD, Hamblin MR (2009) Biphasic dose response in low level light therapy. Dose-Response 7(4):358–383CrossRefPubMedPubMedCentral

Title: Low-level laser therapy in the treatment of pressure ulcers: systematic review
Authors: Renata Saltiel Machado
Suane Viana
Graciele Sbruzzi
Publication date: 01-05-2017
Publisher: Springer London
Published in: Lasers in Medical Science / Issue 4/2017
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-017-2150-9

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Low-level laser therapy in the treatment of pressure ulcers: systematic review

Abstract

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