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Published in: Lasers in Medical Science 4/2005

01-04-2005 | Original Article

Effects of dynamic changes of tissue properties during laser-induced interstitial thermotherapy (LITT)

Authors: S. C. Jiang, X. X. Zhang

Published in: Lasers in Medical Science | Issue 4/2005

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Abstract

A two-dimensional model including the effects of dynamic changes in the physical properties on tissue temperature and damage was developed to describe laser energy transport, heat transfer, and damage accumulation during laser-induced interstitial thermotherapy (LITT). The Monte Carlo method was used to simulate photon transport in a tissue in the nonuniform optical property field, with the finite difference method used to solve the Pennes bioheat equation to calculate the temperature distribution and the Arrhenius equation used to predict the extent of thermal damage. The numerical results showed that the dynamic changes in the optical properties, thermal properties, and blood perfusion rate significantly affected damage volume accumulation and temperature history and should be included in numerical simulations of the LITT treatment.
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Metadata
Title
Effects of dynamic changes of tissue properties during laser-induced interstitial thermotherapy (LITT)
Authors
S. C. Jiang
X. X. Zhang
Publication date
01-04-2005
Publisher
Springer-Verlag
Published in
Lasers in Medical Science / Issue 4/2005
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-004-0324-8

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