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Neurological Sciences

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01-03-2021 | Methotrexate | Letter to the Editor

Intrathecal cytosine arabinoside-induced progression of chronic methotrexate myelopathy

Authors: L. Mikhelashvili, A. Haboosheh, V. Vainstein, A. Lossos

Published in: Neurological Sciences | Issue 3/2021

Excerpt

Dear Editor, …

Byrnes D, Vargas F et al (2019) Complications of intrathecal chemotherapy in adults: single-institution experience in 109 consecutive patients. Journal of Oncology 2019:7. https://doi.org/10.1155/2019/4047617CrossRef

Ying P, Chunhuai W, Huiping W et al (2016) Transverse myelopathy occurring with intrathecal administration of methotrexate and cytarabine chemotherapy: a case report. Oncol Lett 11:4066–4068CrossRef

Juster-Switlyk K, Smith AG, Kovacsovics T, Stephens D, Glenn M, Palmer CA, Quigley EP, Kolb N (2017) MTHFR C677T polymorphism is associated with methotrexate-induced myelopathy risk. Neurology 88(6):603–604. https://doi.org/10.1212/WNL.0000000000003590CrossRefPubMedPubMedCentral

Winfried HA et al (2015) Severe and irreversible myelopathy after concurrent systemic and intrathecal nucleoside analogue treatment for refractory diffuse large B-cell lymphoma: a case report and review of the literature. J Oncol Pharm Practice:1–5. https://doi.org/10.1177/1078155214562268

Lapucci C, Capello E, Romano N, Guolo F, Mavilio N, Roccatagliata L (2018) Rapid ascending necrotizing myelopathy with widespread brain white matter involvement following intrathecal methotrexate and cytosine arabinoside treatment in an adult with T cell acute lymphoblastic leukemia. Ital J Neurol Sci 39:1637–1639CrossRef

Title: Intrathecal cytosine arabinoside-induced progression of chronic methotrexate myelopathy
Authors: L. Mikhelashvili
A. Haboosheh
V. Vainstein
A. Lossos
Publication date: 01-03-2021
Publisher: Springer International Publishing
Keywords: Methotrexate
Methotrexate
Leukemia
Published in: Neurological Sciences / Issue 3/2021
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04647-4

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Intrathecal cytosine arabinoside-induced progression of chronic methotrexate myelopathy

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