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Published in: Neurological Sciences 1/2019

Open Access 01-01-2019 | Review Article

Systematic literature review on the delays in the diagnosis and misdiagnosis of cluster headache

Authors: Alina Buture, Fayyaz Ahmed, Lisa Dikomitis, Jason W. Boland

Published in: Neurological Sciences | Issue 1/2019

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Abstract

Introduction

Patients with cluster headache (CH), the most common trigeminal autonomic cephalalgia, often face delayed diagnosis, misdiagnosis and mismanagement.

Objectives

To identify, appraise and synthesise clinical studies on the delays in diagnosis and misdiagnosis of CH in order to determine its causes and help the management of this condition.

Methods

The systematic review was prepared, conducted and reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis. It was registered with International Prospective Register of Systematic Reviews. A systematic search of different electronic databases (Medline, EMBASE, PsycINFO, PubMed, CINAHL, BNI, HMIC, AMED, HBE and Cochrane Library) was carried out in May 2017. Reference lists of relevant articles were hand searched.

Results

The search identified 201 unique studies. Fifteen studies met the inclusion criteria of which 13 case series studies and two survey studies. Nine studies assessed the delays in diagnosis and misdiagnosis of CH, five studies the delays in diagnosis and one study the misdiagnosis of CH. The studies included 4661 patients. Delays in diagnosis, misdiagnosis and mismanagement have been reported in many European countries, Japan and in the USA with well-developed health services. The patients with CH often visited many different clinicians, surgeons and dentists and received multiple diagnosis prior to being correctly diagnosed.

Conclusion

This systematic review shows that the delays in the diagnosis of CH are a widespread problem, the time to diagnosis still vary from country to country and both patients and physicians are responsible for the delays in diagnosis.
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Metadata
Title
Systematic literature review on the delays in the diagnosis and misdiagnosis of cluster headache
Authors
Alina Buture
Fayyaz Ahmed
Lisa Dikomitis
Jason W. Boland
Publication date
01-01-2019
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 1/2019
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-018-3598-5

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