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Neurological Sciences

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01-08-2018 | Original Article

The relationship with restless legs syndrome, fibromyalgia, and depressive symptoms in migraine patients

Authors: Zehra Akdag Uzun, Semiha Kurt, Hatice Karaer Unaldi

Published in: Neurological Sciences | Issue 8/2018

Abstract

Objective

In this study, we aimed to investigate restless legs syndrome, depression, frequency of fibromyalgia and possible causes of its frequencies, and the relationships among these synergies and migraine’s prodrome, aura, pain, and postdrome symptoms in patients with migraine.

Subjects and methods

The study group included 200 patients previously or recently diagnosed with definite migraine and according to International Headache Society criteria and 200 healthy volunteers. All subjects underwent a medical interview to confirm restless legs syndrome and fibromyalgia, and they were asked to complete Beck Depression and Anxiety Inventory and “severity of restless legs syndrome inventory.”

Results

The frequencies of depressive symptoms and fibromyalgia in the patients with migraine were higher than those of the control group. The mean age of the migraine patients with restless legs syndrome was also higher, and this group had migraine headache for a longer time. There was a statistically significant difference with regard to only generalized anxiety and traveler’s distress, which were features of the migraine, between migraine patients with and without restless legs syndrome. Restless legs syndrome was more common in migraine patients with and without aura and in those with nonspecific white matter lesions in the cranial MRI.

Conclusions

In our study, the greater frequency of restless legs syndrome, depressive symptoms, and fibromyalgia in the patients with migraine supports the role of dopamine, which is common to all three disorders. Interviews focused on these problems among migraine patients may help to decide on the best available treatment modality.

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Title: The relationship with restless legs syndrome, fibromyalgia, and depressive symptoms in migraine patients
Authors: Zehra Akdag Uzun
Semiha Kurt
Hatice Karaer Unaldi
Publication date: 01-08-2018
Publisher: Springer Milan
Published in: Neurological Sciences / Issue 8/2018
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-018-3438-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The relationship with restless legs syndrome, fibromyalgia, and depressive symptoms in migraine patients

Abstract

Objective

Subjects and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Subjects and methods

Results

Conclusions

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