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Published in: Neurological Sciences 1/2018

01-01-2018 | Review Article

Cognitive and behavioral disorders in Parkinson’s disease: an update. II: behavioral disorders

Authors: Luigi Trojano, Costanza Papagno

Published in: Neurological Sciences | Issue 1/2018

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Abstract

Patients with Parkinson’s disease (PD) can experience several behavioral symptoms, such as apathy, agitation, hypersexuality, stereotypic movements, pathological gambling, abuse of antiparkinsonian drugs, and REM sleep behavioral disorders. Psychoses and hallucinations, depression and anxiety disorders, and difficulties in recognizing and experiencing emotions also impair behavior and can cause severe psychosocial problems in patients with PD. Symptoms can be present since early stages of the disease, sometimes even before the appearance of classical motor symptoms, likely in relation to dopamine depletion in basal ganglia and/or to dysfunctions of other neurotrasmitter systems, and others can develop later, in some cases in relation to dopaminergic treatment. In this paper, we review recent literature, with particular attention to the last 5 years, on the main behavioral and emotional disturbances described in PD patients as well as the hypothesized neurofunctional substrate of such impairments. Finally, we provide some suggestions on the most suitable instruments to check and assess PD-associated behavioral defects over time.
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Metadata
Title
Cognitive and behavioral disorders in Parkinson’s disease: an update. II: behavioral disorders
Authors
Luigi Trojano
Costanza Papagno
Publication date
01-01-2018
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 1/2018
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-017-3155-7

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