Published in:
01-11-2015 | Original Article
The association between clinically relevant anxiety and other non-motor symptoms in Parkinson’s disease
Authors:
Si-Ming Jiang, Yong-Sheng Yuan, Qing Tong, Li Zhang, Qin-Rong Xu, Jian Ding, Ke-Zhong Zhang
Published in:
Neurological Sciences
|
Issue 11/2015
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Abstract
Anxiety disorders in patients with Parkinson’s disease (PD) are often missed due to an overlap with other non-motor symptoms. The relationships between anxiety and other non-motor symptoms in PD still remain unclear. We used the Hamilton anxiety rating scale and the Non-motor Symptoms Questionnaire to measure anxiety and the complex range of non-motor symptoms in 99 PD patients. The relationships between anxiety and other PD-related non-motor symptoms were examined through regression analyses. 25 % of PD patients were diagnosed with clinically relevant anxiety. Non-motor symptoms were more prominent in patients with anxiety. Depression, urinary disorders, and sleep disruption were the factors most likely to influence anxiety in PD. Our findings have revealed a strong interplay between anxiety and other non-motor symptoms of PD and have highlighted the need for a holistic approach towards the clinical treatment of this disabling condition.