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01-02-2013 | Original Article

Prevalence of cardiac right left shunts in migraine: a population-based case–control study

Authors: Michael Küper, Kasja Rabe, Dagny Holle, Irini Savidou, Peter Dommes, Markus Frings, Hans Christoph Diener, Zaza Katsarava

Published in: Neurological Sciences | Issue 2/2013

Abstract

We aimed to investigate the prevalence of cardiac right left shunts (RLS) in population-based samples of subjects with migraine with aura (n = 42), migraine without aura (n = 44) and controls without headache (n = 41). Cardiac RLS was assessed with transcranial Doppler sonography with intravenous injection of saline. Prevalence of RLS was highest in migraineurs with aura (45.2%) compared to migraineurs without aura (34.1%) and controls (41.5%). Permanent as opposed to latent RLS was more common among patients with migraine with aura (40.5%) than in patients with migraine without aura (23.3%) or controls (24.4%). Differences did not reach statistical significance between the three groups (p = 0.564 for RLS prevalence, p = 0.349 for prevalence of permanent shunts). Our data implicate a trend towards higher prevalence of RLS with larger shunts in subjects with migraine with aura.

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Title: Prevalence of cardiac right left shunts in migraine: a population-based case–control study
Authors: Michael Küper
Kasja Rabe
Dagny Holle
Irini Savidou
Peter Dommes
Markus Frings
Hans Christoph Diener
Zaza Katsarava
Publication date: 01-02-2013
Publisher: Springer Milan
Published in: Neurological Sciences / Issue 2/2013
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-012-0986-0

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Prevalence of cardiac right left shunts in migraine: a population-based case–control study

Abstract

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Abstract

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