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01-02-2011 | Original Article

Vitamin B12 deficiency associated with symptoms of frontotemporal dementia

Authors: C. Blundo, D. Marin, M. Ricci

Published in: Neurological Sciences | Issue 1/2011

Abstract

We report the case of an elderly patient with cobalamin deficiency who progressively developed cognitive and behavioral symptoms associated with neuropsychiatric disturbances. His neuropsychological profile showed many features suggestive for a frontal-dysexecutive syndrome and was related to a predominant asymmetric (right > left) frontal lobe hypoperfusion. He completely recovered after a treatment with vitamin B12 and follow-up of 7 years showed that his improvement remained stable. Along with the other cases reported in the literature, our case also proves that there are some cases of vitamin B12 deficiency that can manifest with the symptoms of frontotemporal dementia and that they are completely reversible after substitution therapy.

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Title: Vitamin B12 deficiency associated with symptoms of frontotemporal dementia
Authors: C. Blundo
D. Marin
M. Ricci
Publication date: 01-02-2011
Publisher: Springer Milan
Published in: Neurological Sciences / Issue 1/2011
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-010-0419-x

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Vitamin B12 deficiency associated with symptoms of frontotemporal dementia

Abstract

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