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01-07-2012 | Review Article

Axial psoriatic arthritis: an intriguing clinical entity or a subset of an intriguing disease?

Authors: Ennio Lubrano, Antonio Spadaro

Published in: Clinical Rheumatology | Issue 7/2012

Abstract

This article summarizes the state of the art of axial involvement in psoriatic arthritis (axial PsA). The definition and measurement of axial disease in PsA still remain problematic, and this, in turn, could affect the best approach of recognition and treatment of this intriguing subset of the psoriatic disease. Axial PsA has been studied over the last few years looking at the difference in function and radiological finding compared to ankylosing spondylitis (AS), trying to differentiate it from a coincidental AS with psoriasis. Finally, this review has described the diagnosis and treatment of axial PsA reporting the data obtained from the literature.

Moll JM, Wright V (1973) Psoriatic arthritis. Semin Arthritis Rheum 3(1):55–78PubMedCrossRef

Rudwaleit M, van der Heijde D, Landewe R, Listing J, Akkok N, Brandt J et al (2009) The development of Assessment of SpondyloArthritis international Society (ASAS) classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 68(6):777–783PubMedCrossRef

Nash P, Mease PJ, Braun J, van der Heijde D (2005) Seronegative spondyloarthropathies: to lump or to split? Ann Rheum Dis 64(suppl III):ii9–ii13PubMedCrossRef

Hanly JG, Russell ML, Gladman DD (1988) Psoriatic spondyloarthropathy: a long term prospective study. Ann Rheum Dis 47:386–393PubMedCrossRef

Taylor WJ, Zmierczak HG, Helliwell PS (2005) Problems with the definition of axial and peripheral patterns in psoriatic arthritis. J Rheumatol 32:974–978PubMed

Scarpa R, Oriente P, Pucino A et al (1988) The clinical spectrum of psoriatic spondylitis. Br J Rheumatol 27:133–137PubMedCrossRef

Chandran V, Barrett J, Schentag CT, Farewell VT, Gladman DD (2009) Axial psoriatic arthritis: update on a long-term prospective study. J Rheumatol 36:2744–2750PubMedCrossRef

Gladman DD, Brubacher B, Buskila D et al (1993) Psoriatic spondyloarthritis: a clinical, radiographic and HLA study. Clin Invest Med 15:371–375

Queiro R, Sarasqueta C, Torre JC, Tinturè T, Lopez-Lagunas I et al (2001) Comparative analysis of psoriatic spondyloarthropathy between men and women. Rheumatol Int 21:66–68PubMedCrossRef

10.

Queiro R, Belzunegui J, Gonzalez C, De DJ, Sarasqueta C, Torre JC et al (2002) Clinically asymptomatic axial disease in psoriatic spondyloarthropathy. Clin Rheumatol 21:10–13PubMedCrossRef

11.

Palazzi C, Lubrano E, D’Angelo S, Olivieri I (2010) Beyond early diagnosis: occult psoriatic arthritis. J Rheumatol 37(8):1556–1558PubMedCrossRef

12.

Salvarani C, Macchioni P, Cremonesi T, Mantovani W, Battistel B, Rossi F et al (1992) The cervical spine in patients with psoriatic arthritis: a clinical, radiological and immunogenetic study. Ann Rheum Dis 51:73–77PubMedCrossRef

13.

Busquets-Perez N, Rodriguez-Moreno J, Gomez-Vaquero C, Noalla-Solè JM (2012) Relationship between psoriatic arthritis and moderate–severe psoriasis: analysis of a series of 166 psoriatic arthritis patients selected from a hospital population. Clin Rheumatol 31(1):139–143PubMedCrossRef

14.

Perez Alamino R, Maldonado Cocco JA, Citera G, Arturi P, Vasquez-Mellado J, Sampaio-Barros PD et al (2011) Differential features between primary ankylosing spondylitis and spondylitis associated with psoriasis and inflammatory bowel disease. J Rheumatol 38:1656–1660PubMedCrossRef

15.

Taylor WJ, Harrison AA (2004) Could the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) be a valid measure of disease activity in patients with psoriatic arthritis? Arthritis Rheum 51:311–315PubMedCrossRef

16.

Fernandez-Sueiro JL, Willish A, Pertega-Diaz S, Pinto Tasende JA, Fernandez-Lopez JC, Oriero Villar N et al (2010) Validity of the bath ankylosing spondylitis activity index for the evaluation of disease activity in axial psoriatic arthritis. Arthritis Care Res (Hoboken) 62(1):78–85CrossRef

17.

Gladman DD (2007) Axial disease in psoriatic arthritis. Curr Rheumatol Rep 9:455–460PubMedCrossRef

18.

McEwen C, Di Tata D, Lingg C, Porini A, Good A, Rankin T (1971) A comparative study of ankylosing spondylitis and spondylitis accompanying ulcerative colitis, regional enteritis, psoriasis and Reiter’s disease. Arthritis Rheum 14:291–318PubMedCrossRef

19.

Helliwell PS, Hickling P, Wright V (1998) Do the radiological changes of classic ankylosing spondylitis differ from the changes found in the spondylitis associated with inflammatory bowel disease, psoriasis, and reactive arthritis? Ann Rheum Dis 57:135–140PubMedCrossRef

20.

Taccari E, Spadaro A, Riccieri V (1996) Correlations between peripheral and axial radiological changes in patients with psoriatic polyarthritis. Rev Rhum Engl Ed 63(1):17–23PubMed

21.

Lubrano E, Marchesoni A, Olivieri I, D’Angelo S, Spadaro A, Parsons WJ et al (2009) The radiological assessment of axial involvement in psoriatic arthritis: a validation study of the BASRI total and the modified SASSS scoring system. Clin Exp Rheumatol 27:977–980PubMed

22.

Lubrano E, Marchesoni A, Olivieri A, D’Angelo S, Spadaro A, Parsons WJ et al (2009) Psoriatic arthritis spondylitis radiology index: a modified index for radiological assessment of axial involvement in psoriatic arthritis. J Rheumatol 36(5):1006–1011PubMedCrossRef

23.

Gladman DD, Mease PJ, Healy P, Helliwell PS, Fitzgerald O, Cauli A et al (2007) Outcome measures in psoriatic arthritis. J Rheumatol 34:1159–1166PubMed

24.

Gladmann DD, Mease PJ, Strand V, Healy P, Helliwell P, Fitzgerald O et al (2007) Consensus on a core set of domains for psoriatic arthritis. J Rheumatol 34:1167–1170

25.

Baraliakos X, Listing J, Rudwaleit M, Haibel H, Brandt J, Braun J et al (2007) Progression of radiographic damage in patients with ankylosing spondylitis: defining the central role of syndesmophytes. Ann Rheum Dis 66:910–915PubMedCrossRef

26.

Chandran V, Ibrahim A, Thavaneswaran A, Eder L, Helliwell P, Cook R, Gladmann DD (2011) Sensitivity to change of radiographic scoring instruments in axial psoriatic arthritis. Ann Rheum Dis 70(suppl3):239

27.

Williamson L, Dockerty JL, Dalbeth N, McNally E, Ostlere S, Wordsworth BP (2004) Clinical assessment of sacroiliitis and HLA-B27 are poor predictors of sacroiliitis diagnosed by magnetic resonance imaging in psoriatic arthritis. Rheumatol (Oxford) 43(1):85–88CrossRef

28.

Rudwaleit M, Jurik AG, Hermann KG, Landewé R, van der Heijde D, Baraliakos X et al (2009) Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis 68(10):1520–1527PubMedCrossRef

29.

Spadaro A, Riccieri V, Sili Scavalli A, Taccari E (1992) Multiple cervical cord compressions in psoriatic arthritis. Clin Rheumatol 11(1):51–54PubMedCrossRef

30.

Vasey F, Espinoza L (1984) Psoriatic arthropathy. In: Calin A (ed) Spondyloarthropathies. Grune & Stratton, Orlando, pp 151–185

31.

Bennett RM (1979) Psoriatic arthritis. In: McCarty DJ (ed) Arthritis and allied conditions, 9th edn. Lea & Febinger, Philadelphia, pp 645–650

32.

Taylor WJ, Gladman DD, Helliwell PS, Marchesoni A, Mease P, Mielants H, CASPAR Study Group (2006) Classification criteria for psoriatic arthritis. Development of new criteria from a large international study. Arthritis Rheum 54:2665–2673PubMedCrossRef

33.

Khan MA (2003) Clinical features of ankylosing spondylitis. In: Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weismann MH (eds) Rheumatology, 3rd edn. Mosby, Edinburgh, pp 1161–81

34.

Olivieri I, de Portu S, Salvarani C, Cauli A, Lubrano E, Spadaro E et al (2008) The psoriatic arthritis cost evaluation study: a cost-of-illness study on tumour necrosis factor inhibitors in psoriatic arthritis patients with inadequate response to conventional therapy. Rheumatol 47:1664–1670CrossRef

35.

Lubrano E, Spadaro A, Marchesoni A, Olivieri I, Scarpa R, D’Angelo S et al (2011) The effectiveness of a biologic agent on axial manifestations of psoriatic arthritis. A twelve months observational study in a group of patients treated with etanercept. Clin Exp Rheumatol 29(1):80–84PubMed

36.

Ritchlin CT, Kavanaugh A, Gladman DD, Mease PJ, Helliwell P, Boenchke WH et al (2009) Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 68(9):1387–1394PubMedCrossRef

37.

Zochling J, van der Heijde D, Burgos-Vargas R, Collantes E, Davis JC, Dijkmans B et al (2006) ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 65(4):442–452PubMedCrossRef

38.

Gossec L, Smolen JS, Gaujoux-Viala C, Ash Z, Marzo-Ortega H, van der Heijde D et al (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Ann Rheum Dis 71(1):4–12PubMedCrossRef

39.

Braun J, Pham T, Sieper J, Davis J, van der Linden S, Dougados M, van der Heijde D et al (2003) International ASAS consensus statement for the use of anti-tumour necrosis factor agents in patients with ankylosing spondylitis. Ann Rheum Dis 62:817–824PubMedCrossRef

40.

Braun J, Davis J, Dougados M, Siepar J, van der Linden S, van der Heijde D et al (2006) First update of the international ASAS consensus statement for the use of anti-TNF agents in patients with ankylosing spondylitis. Ann Rheum Dis 65:316–320PubMedCrossRef

41.

van der Heijde D, Sieper J, Maksymowych WP, Dougados M, Burgos Vargas R, Landewè R et al (2011) 2010 Update of the international ASAS recommendations for the use of anti-TNF agents in patients with axial spondyloarthritis. Ann Rheum Dis 70(6):905–908PubMedCrossRef

42.

Pipitone N, Kingsley GH, Manzo A, Scott DL, Pitzalis C (2003) Current concepts and new developments in the treatment of psoriatic arthritis. Rheumatol (Oxford) 42(10):1138–1148CrossRef

43.

Baraliakos X, Listing J, Brandt J, Zink A, Alten R, Burmester G et al (2005) Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab. Arthritis Res Ther 7:R439–R444PubMedCrossRef

44.

Brandt J, Khariouzov A, Listing J, Haibel H, Sorensen H, Grassnickel L et al (2003) Six-month results of a double-blind, placebo-controlled trial of etanercept treatment in patients with active ankylosing spondylitis. Arthritis Rheum 48(6):1667–1675PubMedCrossRef

Title: Axial psoriatic arthritis: an intriguing clinical entity or a subset of an intriguing disease?
Authors: Ennio Lubrano
Antonio Spadaro
Publication date: 01-07-2012
Publisher: Springer-Verlag
Published in: Clinical Rheumatology / Issue 7/2012
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-012-1990-8

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