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Published in: Clinical Rheumatology 3/2006

01-05-2006 | Original Article

Serum lipid profile in fibromyalgia women

Authors: Gulcan Gurer, Omer Faruk Sendur, Cavidan Ay

Published in: Clinical Rheumatology | Issue 3/2006

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Abstract

The etiology and pathogenic mechanisms of fibromyalgia (FM) syndrome are unknown. A number of studies have shown that there is an association between some of the musculoskeletal system diseases and hyperlipidemia. The aims of this study were (1) to compare the serum lipid profile among FM and healthy women and (2) to investigate the relationship between serum lipid levels and FM findings. One hundred sixty-four women (82 women with FM as study group and 82 healthy women as control group) were enrolled in the study. The mean serum total cholesterol and low-density lipoprotein cholesterol (LDL-c) were found significantly higher in the FM group than that in the control group (p<0.05). However, There was no statistically significant difference in the mean serum triglyceride, high-density lipoprotein cholesterol (HDL-c), and very low-density lipoprotein cholesterol (VLDL-c) values between the two groups (p>0.05). In the FM group, we could not find a significant correlation between the serum lipid profile values and the FM parameters (p>0.05).
Literature
1.
go back to reference Bernatsky S, Dobkin PL, De Civita M, Penrod JR (2005) Co-morbidity and physician use in fibromyalgia. Swiss Med Wkly 135:76–81PubMed Bernatsky S, Dobkin PL, De Civita M, Penrod JR (2005) Co-morbidity and physician use in fibromyalgia. Swiss Med Wkly 135:76–81PubMed
2.
go back to reference McCarberg B, Barkin RL, Wright JA, Cronan TA, Groessl E, Schmidt SM (2003) Tender points as predictors of distress and the pharmacologic management of fibromyalgia syndrome. Am J Ther 10:176–192CrossRefPubMed McCarberg B, Barkin RL, Wright JA, Cronan TA, Groessl E, Schmidt SM (2003) Tender points as predictors of distress and the pharmacologic management of fibromyalgia syndrome. Am J Ther 10:176–192CrossRefPubMed
3.
go back to reference Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L (1995) The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 38:19–28PubMedCrossRef Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L (1995) The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 38:19–28PubMedCrossRef
4.
go back to reference White KP, Speechley M, Harth M, Ostbye T (1999) The London Fibromyalgia Epidemiology Study: the prevalence of fibromyalgia syndrome in London, Ontario. J Rheumatol 26:1570–1576PubMed White KP, Speechley M, Harth M, Ostbye T (1999) The London Fibromyalgia Epidemiology Study: the prevalence of fibromyalgia syndrome in London, Ontario. J Rheumatol 26:1570–1576PubMed
5.
go back to reference Alarcon GS, Bradley LA (1998) Advances in the treatment of fibromyalgia: current status and future directions. Am J Med Sci 315:397–404CrossRefPubMed Alarcon GS, Bradley LA (1998) Advances in the treatment of fibromyalgia: current status and future directions. Am J Med Sci 315:397–404CrossRefPubMed
6.
go back to reference Rossy LA, Buckelew SP, Dorr N, Hagglund KJ, Thayer JF, McIntosh MJ, Hewett JE, Johnson JC (1999) A meta-analysis of fibromyalgia treatment interventions. Ann Behav Med 21:180–191PubMedCrossRef Rossy LA, Buckelew SP, Dorr N, Hagglund KJ, Thayer JF, McIntosh MJ, Hewett JE, Johnson JC (1999) A meta-analysis of fibromyalgia treatment interventions. Ann Behav Med 21:180–191PubMedCrossRef
7.
go back to reference Thomas E, Blotman F (2002) Are antidepressants effective in fibromyalgia? Joint Bone Spine 69:531–533CrossRefPubMed Thomas E, Blotman F (2002) Are antidepressants effective in fibromyalgia? Joint Bone Spine 69:531–533CrossRefPubMed
8.
go back to reference Cedraschi C, Desmeules J, Rapiti E, Baumgartner E, Cohen P, Finckh A, Allaz AF, Vischer TL (2004) Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management. Ann Rheum Dis 63:290–296CrossRefPubMed Cedraschi C, Desmeules J, Rapiti E, Baumgartner E, Cohen P, Finckh A, Allaz AF, Vischer TL (2004) Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management. Ann Rheum Dis 63:290–296CrossRefPubMed
9.
go back to reference Klemp P, Halland AM, Majoos FL, Steyn K (1993) Musculoskeletal manifestations in hyperlipidemia: a controlled study. Ann Rheum Dis 52:44–48PubMed Klemp P, Halland AM, Majoos FL, Steyn K (1993) Musculoskeletal manifestations in hyperlipidemia: a controlled study. Ann Rheum Dis 52:44–48PubMed
10.
go back to reference Careless DJ, Cohen MG (1993) Rheumatic manifestations of hyperlipidemia and antihyperlipidemia drug therapy. Semin Arthritis Rheum 23:90–98PubMedCrossRef Careless DJ, Cohen MG (1993) Rheumatic manifestations of hyperlipidemia and antihyperlipidemia drug therapy. Semin Arthritis Rheum 23:90–98PubMedCrossRef
11.
go back to reference Struthers GR, Scott DL, Bacon PA, Walton KW (1983) Musculoskeletal disorders in patients with hyperlipidemia. Ann Rheum Dis 42:519–523PubMed Struthers GR, Scott DL, Bacon PA, Walton KW (1983) Musculoskeletal disorders in patients with hyperlipidemia. Ann Rheum Dis 42:519–523PubMed
12.
go back to reference Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P (1990) The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 33:160–172PubMedCrossRef Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P (1990) The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 33:160–172PubMedCrossRef
13.
go back to reference Burkhardt CS, Clark SR, Bennett RM (1991) The Fibromyalgia Impact Questionnaire: development and validation. J Rheumatol 18:728–733PubMed Burkhardt CS, Clark SR, Bennett RM (1991) The Fibromyalgia Impact Questionnaire: development and validation. J Rheumatol 18:728–733PubMed
14.
go back to reference Hedin PJ, Hamme M, Burkhardt CS, Engstrom-Laurent A (1995) The Fibromyalgia Impact Questionnaire, a Swedish translation of a new tool for evaluation of the fibromyalgia patient. Scand J Rheumatol 24:69–75PubMedCrossRef Hedin PJ, Hamme M, Burkhardt CS, Engstrom-Laurent A (1995) The Fibromyalgia Impact Questionnaire, a Swedish translation of a new tool for evaluation of the fibromyalgia patient. Scand J Rheumatol 24:69–75PubMedCrossRef
15.
go back to reference Buskila D, Neumann L (1996) Assessing functional disability and health status of women with fibromyalgia: validation of a Hebrew version of the Fibromyalgia Impact Questionnaire. J Rheumatol 23:903–906PubMed Buskila D, Neumann L (1996) Assessing functional disability and health status of women with fibromyalgia: validation of a Hebrew version of the Fibromyalgia Impact Questionnaire. J Rheumatol 23:903–906PubMed
16.
go back to reference Offenbaecher M, Waltz M, Schoeps P (2000) Validation of a German version of the Fibromyalgia Impact Questionnaire (FIQ-G). J Rheumatol 27:1984–1988PubMed Offenbaecher M, Waltz M, Schoeps P (2000) Validation of a German version of the Fibromyalgia Impact Questionnaire (FIQ-G). J Rheumatol 27:1984–1988PubMed
17.
go back to reference Sarmer S, Ergin S, Yavuzer G (2000) The validity and reliability of the Turkish version of the Fibromyalgia Impact Questionnaire. Rheumatol Int 20:9–12CrossRefPubMed Sarmer S, Ergin S, Yavuzer G (2000) The validity and reliability of the Turkish version of the Fibromyalgia Impact Questionnaire. Rheumatol Int 20:9–12CrossRefPubMed
18.
go back to reference Ozgocmen S, Ardicoglu O (2000) Lipid profile in patients with fibromyalgia and myofascial pain syndromes. Yonsei Med J 41:541–545PubMed Ozgocmen S, Ardicoglu O (2000) Lipid profile in patients with fibromyalgia and myofascial pain syndromes. Yonsei Med J 41:541–545PubMed
19.
go back to reference Hacettepe University Institute of Population Studies (2004), General Directorate of Mother and Child Health/Family Planning. Ministry of Health, Ankara, Turkey, p 65 Hacettepe University Institute of Population Studies (2004), General Directorate of Mother and Child Health/Family Planning. Ministry of Health, Ankara, Turkey, p 65
20.
go back to reference Keel P (1999) Pain management strategies and team approach. Baillieres Best Pract Res Clin Rheumatol 13:493–506CrossRefPubMed Keel P (1999) Pain management strategies and team approach. Baillieres Best Pract Res Clin Rheumatol 13:493–506CrossRefPubMed
21.
go back to reference Sim J, Adams N (1999) Physical and other non-pharmacological interventions for fibromyalgia. Baillieres Best Pract Res Clin Rheumatol 13:507–523CrossRefPubMed Sim J, Adams N (1999) Physical and other non-pharmacological interventions for fibromyalgia. Baillieres Best Pract Res Clin Rheumatol 13:507–523CrossRefPubMed
22.
go back to reference Oliver K, Cronan T (2002) Predictors of exercise behaviors among fibromyalgia patients. Prev Med 35:383–389PubMedCrossRef Oliver K, Cronan T (2002) Predictors of exercise behaviors among fibromyalgia patients. Prev Med 35:383–389PubMedCrossRef
23.
go back to reference Bennett RM, Clark SR, Goldberg L, Nelson D, Bonafede RP, Porter J, Specht D (1989) Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and 133xenon clearance from exercising muscle. Arthritis Rheum 32:454–460PubMedCrossRef Bennett RM, Clark SR, Goldberg L, Nelson D, Bonafede RP, Porter J, Specht D (1989) Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and 133xenon clearance from exercising muscle. Arthritis Rheum 32:454–460PubMedCrossRef
24.
go back to reference Aguilo A, Tauler P, Pilar Guix M, Villa G, Cordova A, Tur JA, Pons A (2003) Effect of exercise intensity and training on antioxidants and cholesterol profile in cyclists. J Nutr Biochem 14:319–325CrossRefPubMed Aguilo A, Tauler P, Pilar Guix M, Villa G, Cordova A, Tur JA, Pons A (2003) Effect of exercise intensity and training on antioxidants and cholesterol profile in cyclists. J Nutr Biochem 14:319–325CrossRefPubMed
25.
go back to reference Hardman AE (1996) Exercise in the prevention of atherosclerotic, metabolic and hypertensive diseases: a review. J Sports Sci 14:201–218CrossRefPubMed Hardman AE (1996) Exercise in the prevention of atherosclerotic, metabolic and hypertensive diseases: a review. J Sports Sci 14:201–218CrossRefPubMed
26.
go back to reference Wood PD (1994) Physical activity, diet, and health: independent and interactive effects. Med Sci Sports Exerc 26:838–843PubMed Wood PD (1994) Physical activity, diet, and health: independent and interactive effects. Med Sci Sports Exerc 26:838–843PubMed
27.
go back to reference Brites FD, Evelson PA, Christiansen MG, Nicol MF, Basílico MJ, Wikinski RW, Llesuy SF (1999) Soccer players under regular training show oxidative stress but an improved plasma antioxidant status. Clin Sci 96:381–385CrossRefPubMed Brites FD, Evelson PA, Christiansen MG, Nicol MF, Basílico MJ, Wikinski RW, Llesuy SF (1999) Soccer players under regular training show oxidative stress but an improved plasma antioxidant status. Clin Sci 96:381–385CrossRefPubMed
Metadata
Title
Serum lipid profile in fibromyalgia women
Authors
Gulcan Gurer
Omer Faruk Sendur
Cavidan Ay
Publication date
01-05-2006
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 3/2006
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-005-0004-5

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