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01-06-2012 | Original Article

Hemodynamic influence of tilting disc valve type on pump performance with the NIPRO-ventricular assist device

Authors: Mitsutoshi Kimura, Takashi Nishimura, Osamu Kinoshita, Koichi Kashiwa, Shunei Kyo, Minoru Ono

Published in: Journal of Artificial Organs | Issue 2/2012

Abstract

The NIPRO-ventricular assist device (NIPRO-VAD) is an external pulsatile flow pump. Formerly, Sorin Carbocast, a monoleaflet tilting disc valve (SC valve), was used at the inlet/outlet parts of the pump, but Medtronic Hall (MH valve) is now used. We studied the differences in performance among pumps with different artificial valves. Six NIPRO pumps with SC valves and six with MH valves were examined using mock circuits. The systolic flow of the pump was measured with the ultrasonic flowmeter by changing the systolic fraction. Six patients wearing the NIPRO-VAD underwent periodic pump exchange from a pump with an SC valve to the one with an MH valve. The pump blood flow was measured at pre- and post-pump exchanges using an ultrasonic flowmeter. Blood pressure, serum LDH and AST levels were also compared before and after the pump exchange. Blood flow was significantly increased by using the NIPRO-VAD with the MH valve as compared to the SC valve in vitro. Under the same drive conditions pump flow tended to increase in six patients. No difference was found in patients’ blood pressure, serum LDH or AST levels when using the SC or MH valve. From these results, the hemodynamic influence on patients due to replacement of the SC valve with the MH valve in the NIPRO-VAD is considered to be insignificant.

Saito S, Matsumiya G, Sakaguchi T, Fujita T, Kuratani T, Ichikawa H, Sawa Y. Fifteen-year experience with Toyobo paracorporeal left ventricular assist system. J Artif Organs. 2009;12:27–34.PubMedCrossRef

Sasaoka T, Kato TS, Komamura K, Takahashi A, Nakajima I, Oda N, Hanatani A, Mano A, Asakura M, Hashimura K, Niwaya K, Funatsu T, Kobayashi J, Kitamura S, Shishido T, Wada K, Miyata S, Nakatani T, Isobe M, Kitakaze M. Improved long-term performance of pulsatile extracorporeal left ventricular assist device. J Cardiol. 2010;56:220–8.PubMedCrossRef

Shiga T, Kinugawa K, Hatano M, Yao A, Nishimura T, Endo M, Kato N, Hirata Y, Kyo S, Ono M, Nagai R. Age and preoperative total bilirubin level can stratify prognosis after extracorporeal pulsatile left ventricular assist device implantation. Circ J. 2011;75:121–8.PubMedCrossRef

Takano H, Taenaka Y, Matsuda T, Umezu M, Nakamura T, Hayashi K, Akutsu T, Manabe H. Development of the clinical ventricular assist system: modification of the blood pump and its evaluation. Jpn J Artif Organs. 1983;12:390–4.

Nishimura T, Kyo S. High-dose carvedilol therapy for mechanical circulatory assisted patients. J Artif Organs. 2010;13:88–91.PubMedCrossRef

Schima H, Reindl C, Stoiber M, Rothy W, Wieselthaler G. Emergency reinforcement of cracked paracorporeal blood pumps. ASAIO J. 2004;50:621–3.PubMedCrossRef

Takano H, Taenaka Y, Nakatani T, Umezu M, Matsuda T, Iwata H, Tanaka T, Noda H, Hayashi K, Takatani S, Nakamura T, Seki J, Akutsu T, Manabe H. Circulatory maintenance with a single artificial heart. Trans Am Soc Artif Intern Organs. 1984;30:550–5.PubMed

Flachskampf FA, O’Shea JP, Griffin BP, Guerrero L, Weyman AE, Thomas JD. Patterns of normal transvalvular regurgitation in mechanical valve prostheses. J Am Coll Cardiol. 1991;18:1493–8.PubMedCrossRef

Shivakumaraswamy T, Mishra P, Radhakrishnan B, Khandekar J, Agrawal N, Patwardhan A, Khandeparkar J. Intravascular hemolysis in patients with normally functioning mechanical heart valves in mitral position. Ind J Thorac Cardiovasc Surg. 2006;22:215–8.CrossRef

10.

Akagawa E, Lee H, Tatsumi E, Homma A, Tsukiya T, Katagiri N, Kakuta Y, Nishinaka T, Mizuno T, Ota K, Kansaku R, Taenaka Y. Effects of mechanical valve orifice direction on the flow pattern in a ventricular assist device. J Artif Organs. 2007;10:85–91.PubMedCrossRef

11.

Nakata M, Masuzawa T, Tatsumi E, Taenaka Y, Nishimura T, Tsukiya T, Takano H, Tsuchimoto K, Ohba K. Characterization and optimization of the flow pattern inside a diaphragm blood pump based on flow visualization techniques. ASAIO J. 1998;44:M714–8.PubMedCrossRef

12.

Lee H, Tatsumi E, Taenaka Y. Flow visualization of a monoleaflet and bileaflet mechanical heart valve in a pneumatic ventricular assist device using a PIV system. ASAIO J. 2010;56:186–93.PubMedCrossRef

Title: Hemodynamic influence of tilting disc valve type on pump performance with the NIPRO-ventricular assist device
Authors: Mitsutoshi Kimura
Takashi Nishimura
Osamu Kinoshita
Koichi Kashiwa
Shunei Kyo
Minoru Ono
Publication date: 01-06-2012
Publisher: Springer Japan
Published in: Journal of Artificial Organs / Issue 2/2012
Print ISSN: 1434-7229
Electronic ISSN: 1619-0904
DOI: https://doi.org/10.1007/s10047-011-0616-2

2024 ASCO Annual Meeting

Springer Medicine

Hemodynamic influence of tilting disc valve type on pump performance with the NIPRO-ventricular assist device

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

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