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Hernia
Published in: Hernia 4/2005

01-12-2005 | Original Article

Fibrin sealing versus stapling of hernia meshes in an onlay model in the rat

Authors: Alexander H. Petter-Puchner, R. Fortelny, R. Mittermayr, W. Öhlinger, H. Redl

Published in: Hernia | Issue 4/2005

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Abstract

Incisional and inguinal hernia repair are among the most common procedures of general surgery. Mesh fixation by means of staples or sutures may lead to severe complications. The use of fibrin sealant (FS) has been suggested as alternative, but data on biocompatibility and adhesive strength of FS in combination with macroporous meshes is limited. Ventral hernia (n=8 per group) was treated in rats in onlay technique with two types of meshes, fibrin sealed or stapled. TI-Mesh (TMxl) extralight and VYPROII (VPII) were tested 17 days post op. No failure in mechanical tests (tensile and burst strength) occurred in sealed or stapled meshes. Histology revealed equally good tissue integration and neovascularization in all groups. Fibrin sealant yields excellent fixation in experimental hernia repair. This rat model is suitable for testing meshes and fixation techniques.
Literature
1.
McGreevy JM, Goodney PP, Birkmeyer CM, Finlayson SR, Laycock WS, Birkmeyer JD (2003) A prospective study comparing the complication rates between laparoscopic and open ventral hernia repairs. Surg Endosc 17:1778–1780CrossRefPubMed
2.
Neumayer L, Giobbie-Hurder A, Jonasson O, Fitzgibbons R Jr, Dunlop D, Gibbs J, Reda D, Henderson W (2004) Open mesh versus laparoscopic mesh repair of inguinal hernia. N Engl J Med 350:1819–1827CrossRefPubMed
3.
Smith AI, Royston CM, Sedman PC (1999) Stapled and nonstapled laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair. A prospective randomized trial. Surg Endosc 13:804–806CrossRefPubMed
4.
Douglas JM, Young WN, Jones DB (2002) Lichtenstein inguinal herniorrhaphy using sutures versus tacks. Hernia 6:99–101CrossRefPubMed
5.
Junge K, Klinge U, Klosterhalfen B, Mertens PR, Rosch R, Schachtrupp A, Ulmer F, Schumpelick V (2002) Influence of mesh materials on collagen deposition in a rat model. J Invest Surg 15:319–328CrossRefPubMed
6.
Ladurner R, Mussack T (2004) Small bowel perforation due to protruding spiral tackers: a rare complication in laparoscopic incisional hernia repair. Surg Endosc 18:1001PubMed
7.
Paajanen H (2002) Do absorbable mesh sutures cause less chronic pain than nonabsorbable sutures after Lichtenstein inguinal herniorraphy? Hernia 6:26–28CrossRefPubMed
8.
Katkhouda N, Mavor E, Friedlander MH, Mason RJ, Kiyabu M, Grant SW, Achanta K, Kirkman EL, Narayanan K, Essani R (2001) Use of fibrin sealant for prosthetic mesh fixation in laparoscopic extraperitoneal inguinal hernia repair. Ann Surg 233:18–25CrossRefPubMed
9.
Pans A, Pierard GE (1992) A comparison of intraperitoneal prostheses for the repair of abdominal muscular wall defects in rats. Eur Surg Res 24:54–60PubMedCrossRef
10.
Scheidbach H, Tamme C, Tannapfel A, Lippert H, Kockerling F (2004) In vivo studies comparing the biocompatibility of various polypropylene meshes and their handling properties during endoscopic total extraperitoneal (TEP) patchplasty: an experimental study in pigs. Surg Endosc 18:211–220CrossRefPubMed
11.
Klinge U, Klosterhalfen B, Muller M, Ottinger AP, Schumpelick V (1998) Shrinking of polypropylene mesh in vivo: an experimental study in dogs. Eur J Surg 164:965–969CrossRefPubMed
12.
Post S, Weiss B, Willer M, Neufang T, Lorenz D (2004) Randomized clinical trial of lightweight composite mesh for Lichtenstein inguinal hernia repair. Br J Surg 91:44–48CrossRefPubMed
13.
Greca FH, de Paula JB, Biondo-Simoes ML, da Costa FD, da Silva AP, Time S, Mansur A (2001) The influence of differing pore sizes on the biocompatibility of two polypropylene meshes in the repair of abdominal defects. Experimental study in dogs. Hernia 5:59–64CrossRefPubMed
14.
Klinge U, Klosterhalfen B, Muller M, Schumpelick V (1999) Foreign body reaction to meshes used for the repair of abdominal wall hernias. Eur J Surg 165:665–673PubMedCrossRef
15.
Pandit AS, Henry JA (2004) Design of surgical meshes—an engineering perspective. Technol Health Care 12:51–65PubMed
16.
Beets GL, Go PM, van Mameren H (1996) Foreign body reactions to monofilament and braided polypropylene mesh used as preperitoneal implants in pigs. Eur J Surg 162:823–825PubMed
17.
Badylak S, Kokini K, Tullius B, Simmons-Byrd A, Morff R (2002) Morphologic study of small intestinal submucosa as a body wall repair device. J Surg Res 103:190–202CrossRefPubMed
18.
LeBlanc KA (2004) Laparoscopic incisional and ventral hernia repair: complications-how to avoid and handle. Hernia
19.
Vermeulen J, Alwayn I, Stassen LP (2003) Prolonged abdominal wall pain caused by transfascial sutures used in the laparoscopic repair of incisional hernia. Surg Endosc 17:1497CrossRefPubMed
20.
Canonico S (2003) The use of human fibrin glue in the surgical operations. Acta Biomed Ateneo Parmense 74(Suppl 2):21–25
21.
Canonico S, Sciaudone G, Pacifico F, Santoriello A (1999) Inguinal hernia repair in patients with coagulation problems: prevention of postoperative bleeding with human fibrin glue. Surgery 125:315–317CrossRefPubMed
22.
Toosie K, Gallego K, Stabile BE, Schaber B, French S, de Virgilio C (2000) Fibrin glue reduces intra-abdominal adhesions to synthetic mesh in a rat ventral hernia model. Am Surg 66:41–45PubMed
23.
Fernandez LR, Garcia SJ, Ortega DP, Martin Lucas FJ, Ruiz de Adana JC, Limones EM (2001) Tissucol application in dermolipectomy and incisional hernia repair. Int Surg 86:240–245PubMed
24.
Rosch R, Junge K, Quester R, Klinge U, Klosterhalfen B, Schumpelick V (2003) VYPROII mesh in hernia repair: impact of polyglactin on long-term incorporation in rats. Eur Surg Res 35:445–450CrossRefPubMed
Metadata
Title
Fibrin sealing versus stapling of hernia meshes in an onlay model in the rat
Authors
Alexander H. Petter-Puchner
R. Fortelny
R. Mittermayr
W. Öhlinger
H. Redl
Publication date
01-12-2005
Publisher
Springer-Verlag
Published in
Hernia / Issue 4/2005
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-005-0009-7

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