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01-05-2004 | Original Article

Effect of prosthetic material on adhesion formation after laparoscopic ventral hernia repair in a porcine model

Authors: E. C. Borrazzo, M. F. Belmont, D. Boffa, D. L. Fowler

Published in: Hernia | Issue 2/2004

Abstract

Intraperitoneal placement of prosthetic mesh causes adhesion formation after laparoscopic incisional hernia repair. A prosthesis that prevents or reduces adhesion formation is desirable. In this study, 21 pigs were randomized to receive laparoscopic placement of plain polypropylene mesh (PPM), expanded polytetrafluoroethylene (ePTFE), or polypropylene coated on one side with a bioresorbable adhesion barrier (PPM/HA/CMC). The animals were sacrificed after 28 days and evaluated for adhesion formation. Mean area of adhesion formation was 14% (SD±15) in the PPM/HA/CMC group, 40% (SD±17) in the PPM group, and 41% (SD±39) in the ePTFE group. The difference between PPM/HA/CMC and PPM was significant (P=0.013). A new visceral layer of mesothelium was present in seven out of seven PPM/HA/CMC cases, six out of seven PPM cases, and two out of seven ePTFE cases. Thus, laparoscopic placement of PPM/HA/CMC reduces adhesion formation compared to other mesh types used for laparoscopic ventral hernia repairs.

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Title: Effect of prosthetic material on adhesion formation after laparoscopic ventral hernia repair in a porcine model
Authors: E. C. Borrazzo
M. F. Belmont
D. Boffa
D. L. Fowler
Publication date: 01-05-2004
Publisher: Springer-Verlag
Published in: Hernia / Issue 2/2004
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI: https://doi.org/10.1007/s10029-003-0181-6

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Effect of prosthetic material on adhesion formation after laparoscopic ventral hernia repair in a porcine model

Abstract

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