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European Child & Adolescent Psychiatry
Published in: European Child & Adolescent Psychiatry 3/2016

Open Access 01-03-2016 | Original Contribution

Health-related quality of life of children with attention-deficit/hyperactivity disorder versus children with diabetes and healthy controls

Authors: David Coghill, Paul Hodgkins

Published in: European Child & Adolescent Psychiatry | Issue 3/2016

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Abstract

The impact of attention-deficit/hyperactivity disorder (ADHD) on health-related quality of life (HRQoL) is reported to be similar to that of other mental health and physical disorders. In this cross-sectional study, we hypothesized that children with ADHD and children with type 1 diabetes mellitus (T1DM) would have significantly worse HRQoL compared with healthy children, and that better clinical status in ADHD and T1DM would be associated with better HRQoL. Children were recruited from three outpatient services in Scotland. Responses to two frequently used validated HRQoL instruments, the Paediatric Quality of Life Inventory (PedsQL) and Child Health and Illness Profile-child edition (CHIP-CE), were obtained from parents/carers and children (6–16 years) with/without ADHD or T1DM. Child and parent/carer-completed HRQoL measurements were evaluated for 213 children with ADHD, 58 children with T1DM and 117 healthy children (control group). Significantly lower self and parent/carer ratings were observed across most PedsQL (P < 0.001) and CHIP-CE (P < 0.05) domains (indicating reduced HRQoL) for the ADHD group compared with the T1DM and control groups. Parent/carer and child ratings were significantly correlated for both measures of HRQoL (PedsQL total score: P < 0.001; CHIP-CE all domains: P < 0.001), but only with low-to-moderate strength. Correlation between ADHD severity and HRQoL was significant with both PedsQL and CHIP-CE for all parent/carer (P < 0.01) and most child (P < 0.05) ratings; more ADHD symptoms were associated with poorer HRQoL. These data demonstrate that ADHD has a significant impact on HRQoL (as observed in both parent/carer and child ratings), which seems to be greater than that for children with T1DM.
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Metadata
Title
Health-related quality of life of children with attention-deficit/hyperactivity disorder versus children with diabetes and healthy controls
Authors
David Coghill
Paul Hodgkins
Publication date
01-03-2016
Publisher
Springer Berlin Heidelberg
Published in
European Child & Adolescent Psychiatry / Issue 3/2016
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI
https://doi.org/10.1007/s00787-015-0728-y

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