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Published in: European Child & Adolescent Psychiatry 8/2006

01-12-2006 | BRIEF REPORT

Adjunctive olanzapine treatment in bipolar adolescents responding insufficiently to mood stabilizers

Four case reports

Authors: F. Neslihan İnal Emiroglu, MD, Özlem Gencer, MD, Aylin Özbek, MD

Published in: European Child & Adolescent Psychiatry | Issue 8/2006

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Abstract

This report was aimed to evaluate the efficacy of olanzapine treatment as an adjunct therapy to mood stabilizers in the treatment of four adolescents responding insufficiently to mood stabilizers. All patients were diagnosed with bipolar I disorder according to DSM IV criteria. YMRS (Young mania rating scale) and CGI (Clinical global impression, improvement and therapeutic effectiveness scales) were used to evaluate overall response of the episode to the drugs. All patients with no adequate response to mood stabilizers did respond to adjunctive olanzapine treatment (10–30 mg/per day). It has been suggested that antipsychotics may be useful as an adjunct to mood stabilisers in bipolar disorder. However, further research is warranted regarding the use of atypical antipsychotics in children and adolescents.
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Metadata
Title
Adjunctive olanzapine treatment in bipolar adolescents responding insufficiently to mood stabilizers
Four case reports
Authors
F. Neslihan İnal Emiroglu, MD
Özlem Gencer, MD
Aylin Özbek, MD
Publication date
01-12-2006
Publisher
Steinkopff-Verlag
Published in
European Child & Adolescent Psychiatry / Issue 8/2006
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI
https://doi.org/10.1007/s00787-006-0552-5

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