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Published in: Journal of Orthopaedic Science 4/2011

01-07-2011 | Case report

Simultaneous bilateral subtrochanteric fractures following risedronate therapy

Authors: Mikko T. Ovaska, Tatu J. Mäkinen, Rami Madanat

Published in: Journal of Orthopaedic Science | Issue 4/2011

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Excerpt

Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis, and have been shown to be highly effective in reducing the risk of vertebral and hip fractures [1]. The mechanism of action of bisphosphonates is based on the inhibition of osteoclast function and induction of osteoclast apoptosis. In experimental studies, prolonged suppression of bone turnover has been shown to result in accumulation of microdamage and increased bone fragility [2, 3]. …
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Metadata
Title
Simultaneous bilateral subtrochanteric fractures following risedronate therapy
Authors
Mikko T. Ovaska
Tatu J. Mäkinen
Rami Madanat
Publication date
01-07-2011
Publisher
Springer Japan
Published in
Journal of Orthopaedic Science / Issue 4/2011
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI
https://doi.org/10.1007/s00776-011-0058-y

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