Top

Published in:

01-06-2017 | Brief Report

Genotype analysis of ORF 62 identifies varicella-zoster virus infections caused by a vaccine strain in children

Authors: Byung Ok Kwak, Hoan Jong Lee, Hyun Mi Kang, Chi Eun Oh, Eun Hwa Choi

Published in: Archives of Virology | Issue 6/2017

Abstract

This study was performed to differentiate vaccine-type strains from wild-type strains and determine the genotype of varicella-zoster virus (VZV) in 51 Korean children. A sequencing analysis of ORF 62 identified two cases of herpes zoster caused by the vaccine-type virus, without a previous history of varicella, 22 months and 5 months after VZV vaccination. The wild-type strain was identified in the remaining children. A genotype analysis of ORF 22 amino acids revealed genotype J in all children except one. Genotype E was identified in an infant with varicella imported from Egypt.

Davison AJ, Scott JE (1986) The complete DNA sequence of varicella-zoster virus. J Gen Virol 67:1759–1816CrossRefPubMed

Schmidt-Chanasit J, Sauerbrei A (2011) Evolution and world-wide distribution of varicella-zoster virus clades. Infect Genet Evol 11:1–10CrossRefPubMed

Takahashi M, Otsuka T, Okuno Y, Asano Y, Yazaki T, Isomura S (1974) Live vaccine used to prevent the spread of varicella in children in hospital. Lancet 304:1288–1290CrossRef

Nguyen HQ, Jumaan AO, Seward JF (2005) Decline in mortality due to varicella after implementation of varicella vaccination in the United States. N Engl J Med 352:450–458CrossRefPubMed

Kim SH, Lee HJ, Park SE, Oh SH, Lee SY, Choi EH (2010) Seroprevalence rate after one dose of varicella vaccine in infants. J Infect 61:66–72CrossRefPubMed

Galea SA, Sweet A, Beninger P, Steinberg SP, LaRussa PS, Gershon AA, Sharrar RG (2008) The safety profile of varicella vaccine: a 10-year review. J Infect Dis 197:S165–S169CrossRefPubMed

Sauerbrei A, Eichhorn U, Gawellek S, Egerer R, Schacke M, Wutzler P (2003) Molecular characterisation of varicella-zoster virus strains in Germany and differentiation from the Oka vaccine strain. J Med Virol 71:313–319CrossRefPubMed

Sauerbrei A, Rubtcova E, Wutzler P, Schmid DS, Loparev VN (2004) Genetic profile of an Oka varicella vaccine virus variant isolated from an infant with zoster. J Clin Microbiol 42:5604–5608CrossRefPubMedPubMedCentral

LaRussa P, Lungu O, Hardy I, Gershon A, Steinberg S, Silverstein S (1992) Restriction fragment length polymorphism of polymerase chain reaction products from vaccine and wild-type varicella-zoster virus isolates. J Virol 66:1016–1020PubMedPubMedCentral

10.

LaRussa P, Steinberg S, Arvin A, Dwyer D, Burgess M, Menegus M, Rekrut K, Yamanishi K, Gershon A (1998) Polymerase chain reaction and restriction fragment length polymorphism analysis of varicella-zoster virus isolates from the United States and other parts of the world. J Infect Dis 178:S64–S66CrossRefPubMed

11.

Argaw T, Cohen JI, Klutch M, Lekstrom K, Yoshikawa T, Asano Y, Krause PR (2000) Nucleotide sequences that distinguish Oka vaccine from parental Oka and other varicella-zoster virus isolates. J Infect Dis 181:1153–1157CrossRefPubMed

12.

Loparev VN, Argaw T, Krause PR, Takayama M, Schmid DS (2000) Improved identification and differentiation of varicella-zoster virus (VZV) wild-type strains and an attenuated varicella vaccine strain using a VZV open reading frame 62-based PCR. J Clin Microbiol 38:3156–3160PubMedPubMedCentral

13.

Loparev VN, Gonzalez A, Deleon-Carnes M, Tipples G, Fickenscher H, Torfason EG, Schmid DS (2004) Global identification of three major genotypes of varicella-zoster virus: longitudinal clustering and strategies for genotyping. J Virol 78:8349–8358CrossRefPubMedPubMedCentral

14.

Loparev VN, Rubtcova E, Seward JF, Levin MJ, Schmid DS (2007) DNA sequence variability in isolates recovered from patients with postvaccination rash or herpes zoster caused by Oka varicella vaccine. J Infect Dis 195:502–510CrossRefPubMed

15.

Gershon AA, Gershon MD (2013) Pathogenesis and current approaches to control of varicella-zoster virus infections. Clin Microbiol Rev 26:728–743CrossRefPubMedPubMedCentral

16.

Bhalla P, Forrest GN, Gershon M, Zhou Y, Chen J, LaRussa P, Steinberg S, Gershon AA (2014) Disseminated persistent and fatal infection due to the vaccine strain (vOka) of varicella-zoster virus in an adult following stem cell transplantation. Clin Infect 60:1068–1074

17.

Thomas SL, Hall AJ (2004) What does epidemiology tell us about risk factors for herpes zoster? Lancet Infect Dis 4:26–33CrossRefPubMed

18.

Adler AL, Casper C, Boeckh M, Heath J, Zerr DM (2008) An outbreak of varicella with likely breakthrough disease in a population of pediatric cancer patients. Infect Control Hosp Epidemiol 29:866–870CrossRefPubMed

19.

Liang MG, Heidelberg KA, Jacobson RM, McEvoy MT (1998) Herpes zoster after varicella immunization. J Am Acad Dermatol 38:761–763CrossRefPubMed

20.

Uebe B, Sauerbrei A, Burdach S, Horneff G (2002) Herpes zoster by reactivated vaccine varicella zoster virus in a healthy child. Eur J Pediatr 161:442–444CrossRefPubMed

21.

Ota K, Kim V, Lavi S, Ford-Jones EL, Tipples G, Scolnik D, Tellier R (2008) Vaccine-strain varicella zoster virus causing recurrent herpes zoster in an immunocompetent 2-year-old. Pediatr Infect Dis J 27:847–848CrossRefPubMed

22.

Gomi Y, Ozaki T, Nishimura N, Narita A, Suzuki M, Ahn J, Watanabe N, Koyama N, Ushida H, Yasuda N, Nakane K, Funahashi K, Fuke I, Takamizawa A, Ishikawa T, Yamanishi K, Takahashi M (2008) DNA sequence analysis of varicella-zoster virus gene 62 from subclinical infections in healthy children immunized with the Oka varicella vaccine. Vaccine 26:5627–5632CrossRefPubMed

23.

Iyer S, Mittal MK, Hodinka RL (2009) Herpes zoster and meningitis resulting from reactivation of varicella vaccine virus in an immunocompetent child. Ann Emerg Med 53:792–795CrossRefPubMed

24.

Chouliaras G, Spoulou V, Quinlivan M, Breuer J, Theodoridou M (2010) Vaccine-associated herpes zoster ophthalmicus [correction of opthalmicus] and encephalitis in an immunocompetent child. Pediatrics 125:e969–e972CrossRefPubMed

25.

Han JY, Hanson DC, Way SS (2011) Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child. Pediatr Infect Dis J 30:266–268CrossRefPubMed

26.

Chaves SS, Haber P, Walton K, Wise RP, Izurieta HS, Schmid DS, Seward JF (2008) Safety of varicella vaccine after licensure in the United States: experience from reports to the vaccine adverse event reporting system, 1995–2005. J Infect Dis 197:S170–S177CrossRefPubMed

27.

Hambleton S, Steinberg SP, Larussa PS, Shapiro ED, Gershon AA (2008) Risk of herpes zoster in adults immunized with varicella vaccine. J Infect Dis 197:S196–S199CrossRefPubMed

28.

Sauerbrei A, Zell R, Harder M, Wutzler P (2006) Genotyping of different varicella vaccine strains. J Clin Virol 37:109–117CrossRefPubMed

29.

Loparev VN, Rubtcova EN, Bostik V, Govil D, Birch CJ, Druce JD, Schmid DS, Croxson MC (2007) Identification of five major and two minor genotypes of varicella-zoster virus strains: a practical two-amplicon approach used to genotype clinical isolates in Australia and New Zealand. J Virol 81:12758–12765CrossRefPubMedPubMedCentral

30.

Breuer J, Grose C, Norberg P, Tipples G, Schmid DS (2010) A proposal for a common nomenclature for viral clades that form the species varicella-zoster virus: summary of VZV Nomenclature Meeting 2008, Barts and the London School of Medicine and Dentistry, 24–25 July 2008. J Gen Virol 91:821–828CrossRefPubMedPubMedCentral

31.

Liu J, Wang M, Gan L, Yang S, Chen J (2009) Genotyping of clinical varicella-zoster virus isolates collected in China. J Clin Microbiol 47:1418–1423CrossRefPubMedPubMedCentral

32.

Marshall HS, McIntyre P, Richmond P, Buttery JP, Royle JA, Gold MS, Wood N, Elliott EJ, Zurynski Y, Toi CS (2013) Changes in patterns of hospitalized children with varicella and of associated varicella genotypes after introduction of varicella vaccine in Australia. Pediatr Infect Dis J 32:530–537CrossRefPubMed

33.

Choi YJ, Kim KH, Oh MD (2010) Genotype of varicella zoster virus isolated from Korean elderly patients with herpes zoster. Infect Chemother 42:162–170CrossRef

34.

Kim KH, Choi YJ, Song KH, Park WB, Jeon JH, Park SW, Kim HB, Kim NJ, Oh MD (2011) Genotype of varicella-zoster virus isolates in South Korea. J Clin Microbiol 49:1913–1916CrossRefPubMedPubMedCentral

Title: Genotype analysis of ORF 62 identifies varicella-zoster virus infections caused by a vaccine strain in children
Authors: Byung Ok Kwak
Hoan Jong Lee
Hyun Mi Kang
Chi Eun Oh
Eun Hwa Choi
Publication date: 01-06-2017
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 6/2017
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-017-3276-6

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 6/2017

Complete genome sequence of sunflower ring blotch virus, a new potyvirus infecting sunflower in Argentina

Desmodium mottle virus, the first legumovirus (genus Begomovirus) from East Africa

First isolation and characterization of pteropine orthoreoviruses in fruit bats in the Philippines

Association of Toll-like receptor 3 gene polymorphism with the severity of enterovirus 71 infection in Chinese children

Heat shock protein 70 in lung and kidney of specific-pathogen-free chickens is a receptor-associated protein that interacts with the binding domain of the spike protein of infectious bronchitis virus

Complete nucleotide sequence and genome organization of peach virus D, a putative new member of the genus Marafivirus

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials