Top

Published in:

01-11-2016 | Brief Report

Bovine leukemia virus becomes established in dairy herds before the first lactation

Authors: Ramiro Merlini, Gerónimo Gutiérrez, Irene Alvarez, Juan Pablo Jaworski, Hugo Carignano, Mario Poli, Luc Willems, Karina Trono

Published in: Archives of Virology | Issue 11/2016

Abstract

In this work, we studied seven groups of pregnant heifers from a consortium of dairy farms heavily infected with bovine leukemia virus (BLV). ELISA testing showed that the seroprevalence ranges of BLV in heifers between 36.1 and 66.5 %. No significant differences in proviral load were found when comparing heifers with adult cattle. Before their first delivery, more than 9.8 % of heifers show a high proviral load. Because BLV infection can occur during the first two years of life, the rationale of any strategy should be to take action as early as possible after birth.

Gutiérrez G, Carignano H, Alvarez I, Martinez C, Porta N, Politzki R, Gammella M, Lomónaco M, Fondevila N, Poli M, Trono K (2012) Bovine leukemia virus p24 antibodies reflect blood proviral load. BMC Vet Res 8:187. doi:10.1186/1746-6148-8-187 CrossRefPubMedPubMedCentral

Walsh RB, Kelton DF, Hietala SK, Duffield TF (2013) Evaluation of enzyme-linked immunosorbent assays performed on milk and serum samples for detection of neosporosis and leukosis in lactating dairy cows. Can Vet J 54:347–352PubMedPubMedCentral

Bartlett PC, Sordillo LM, Byrem TM, Norby B, Grooms DL, Swenson CL, Zalucha J, Erskine RJ (2014) Options for the control of bovine leukemia virus in dairy cattle. J Am Vet Med Assoc 244:914–922. doi:10.2460/javma.244.8.914 CrossRefPubMed

Castellano A, Goizueta M (2014) Valor agregado institucional: Captación de valor económico de innovaciones tecnológicas. Asociación Argentina de Economía Agraria. http://inta.gob.ar/sites/default/files/script-tmp-inta_captacion_valor_economico_de_innovaciones_tecnol.pdf. Accessed 3 Feb 2016

Ott SL, Johnson R, Wells SJ (2003) Association between bovine-leukosis virus seroprevalence and herd-level productivity on US dairy farms. Prev Vet Med 61:249–262. doi:10.1016/j.prevetmed.2003.08.003 CrossRefPubMed

Gutiérrez G, Alvarez I, Merlini R, Rondelli F, Trono K (2014) Dynamics of perinatal bovine leukemia virus infection. BMC Vet Res 10:82. doi:10.1186/1746-6148-10-82 CrossRefPubMedPubMedCentral

Gutiérrez G, Alvarez I, Politzki R, Lomónaco M, Dus Santos MJ, Rondelli F, Fondevila N, Trono K (2011) Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle. Vet Microbiol 151:255–263. doi:10.1016/j.vetmic.2011.03.035 CrossRefPubMed

Trono KG, Pérez-Filgueira DM, Duffy S, Borca MV, Carrillo C (2001) Seroprevalence of bovine leukemia virus in dairy cattle in Argentina: comparison of sensitivity and specificity of different detection methods. Vet Microbiol 83:235–248. doi:10.1016/S0378-1135(01)00420-5 CrossRefPubMed

Lomónaco M, Alvarez I, Martínez C, Porta N, Merlini R, Carignano H, Gutiérrez G, Trono K (2014) Epidemiological features of BLV natural infection. Retrovirology 11(Suppl 1):P45. doi:10.1186/1742-4690-11-S1-P45 CrossRefPubMedCentral

10.

Gillet NA, Gutiérrez G, Rodriguez SM, De Brogniez A, Renotte N, Alvarez I, Trono K, Willems L (2013) Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection. PLoS Pathog 9:e1003687. doi:10.1371/journal.ppat.1003687 CrossRefPubMedPubMedCentral

11.

Gutiérrez G, Lomónaco M, Alvarez I, Fernandez F, Trono K (2015) Characterization of colostrum from dams of BLV endemic dairy herds. Vet Microbiol 177:366–369. doi:10.1016/j.vetmic.2015.03.001 CrossRefPubMed

12.

Buehring GC, Shen HM, Jensen HM, Jin DL, Hudes M, Block G (2015) Exposure to bovine leukemia virus is associated with breast cancer: a case–control study. PLoS One 10:e0134304. doi:10.1371/journal.pone.0134304 CrossRefPubMedPubMedCentral

13.

Achachi A, Florins A, Gillet N, Debacq C, Urbain P, Foutsop GM, Vandermeers F, Jasik A, Reichert M, Kerkhofs P, Lagneaux L, Burny A, Kettmann R, Willems L (2005) Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo. Proc Natl Acad Sci USA 102:10309–10314. doi:10.1073/pnas.0504248102 CrossRefPubMedPubMedCentral

14.

Gutiérrez G, Rodriguez S, Vilor A, Gillet N, DeBrogniez A, Trono K, Willems L (2015) An efficient vaccine against bovine leukemia virus. Retrovirology 12(Suppl 1):P3. doi:10.1186/1742-4690-12-S1-P3 CrossRefPubMedCentral

Title: Bovine leukemia virus becomes established in dairy herds before the first lactation
Authors: Ramiro Merlini
Gerónimo Gutiérrez
Irene Alvarez
Juan Pablo Jaworski
Hugo Carignano
Mario Poli
Luc Willems
Karina Trono
Publication date: 01-11-2016
Publisher: Springer Vienna
Published in: Archives of Virology / Issue 11/2016
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-016-2973-x

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 11/2016

Prevalence and genomic analysis of infectious hypodermal and hematopoietic necrosis virus (IHHNV) in Litopenaeus vannamei shrimp farmed in Shanghai, China

Simple and efficient ultrafiltration method for purification of rotavirus VP6 oligomeric proteins

“Cytoplasmic domain effects on exposure of co-receptor-binding sites of HIV-1 Env”

Genetic and phylogenetic analysis of a novel parvovirus isolated from chickens in Guangxi, China

A real-time RT-PCR for rapid detection and quantification of mosquito-borne alphaviruses

Molecular detection and genome characterization of porcine circovirus type 2 in rats captured on commercial swine farms

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials